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Intracardiac thrombus associated with resistance to activated protein C

Published online by Cambridge University Press:  19 August 2008

Bernd Kohlhase ,
Deniz Kececioglu  and
Ulrike Nowak-Göttl
Bernd Kohlhase
Affiliation:
Department of Pediatric Cardiology, University Children's Hospital, Münster, Germany
Deniz Kececioglu*
Affiliation:
Department of Pediatric Cardiology, University Children's Hospital, Münster, Germany
Ulrike Nowak-Göttl
Affiliation:
Department of Pediatric Haematology/Oncology, University Children's Hospital, Münster, Germany
*
Deniz Kececioglu, MD. Westfälische Wilhelms-Universität Klinik und Poliklinik für Kinderheilkunde/Kinderkardiologie, Albert-Schweitzer-Str33, D-48 129 Münster, Germany. Tel: 0049-251/837705 Fax: 0049-251/837765
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Summary

Formation of thrombus in the heart is a rare event in children. Genetic risk factors determined for thrombophilia with additional exogenous risk factors may, none the less, promote cardiac thrombosis. We report on a boy without predisposing cardiac disease, heterozygous for resistance to activated protein C, who developed multiple thrombuses attached to the mitral valve which led to recurrent arterial throm boembolism. In addition this patient showed enhanced levels of lipoprotein (a).

Keywords

Intracadiac thrombosisactivated Protein C
Type
Brief Reports
Information
Cardiology in the Young , Volume 8 , Issue 1 , January 1998 , pp. 116 - 118
Copyright
Copyright © Cambridge University Press 1998

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References

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