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Exercise and β-blocker therapy recommendations for inherited arrhythmogenic conditions

Published online by Cambridge University Press:  23 September 2015

Susan Christian ,
Martin Somerville ,
Sherry Taylor  and
Joseph Atallah
Susan Christian*
Affiliation:
Department of Medical Genetic, University of Alberta, Edmonton, Alberta, Canada
Martin Somerville
Affiliation:
Department of Medical Genetic, University of Alberta, Edmonton, Alberta, Canada
Sherry Taylor
Affiliation:
Department of Medical Genetic, University of Alberta, Edmonton, Alberta, Canada
Joseph Atallah
Affiliation:
Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
*
Correspondence to: S. Christian, MSc CGC, Department of Medical Genetic, University of Alberta, 826 Medical Sciences Building, Edmonton, Alberta T6G 2H7, Canada. Tel: +1 780 407 1015; Fax: +1 780 407 1761; E-mail: Susan.Christian@albertahealthservices.ca
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Abstract

Background

Management of individuals with long QT syndrome, catecholaminergic polymorphic ventricular tachycardia, hypertrophic cardiomyopathy, and arrhythmogenic right ventricular cardiomyopathy may involve exercise restriction and/or β-blocker therapy.

Objective

This study assessed the practices of a group of paediatric electrophysiologists regarding the management of genotype-positive/phenotype-positive and genotype-positive/phenotype-negative individuals with these conditions.

Method

An online survey was circulated to members of the Pediatric and Congenital Electrophysiology Society in May, 2014. The survey included questions addressing the respondents’ approach regarding exercise recommendations and prescription of β-blocker therapy.

Results

A total of 45 cardiologists completed the survey. The majority of respondents restricted symptomatic patients from competitive sports; however, only approximately half restricted phenotype-negative mutation carriers from this level of activity. Recommendations were less consistent regarding other types of activities. A trend was identified regarding physician physical activity and exercise recommendations for phenotype-negative mutation carriers. Less-active physicians were more likely to restrict exercise. β-blocker therapy was discussed by the majority of respondents for symptomatic patients and a significant number of asymptomatic patients.

Conclusion

Exercise restriction for patients with long QT syndrome, catecholaminergic polymorphic ventricular tachycardia, hypertrophic cardiomyopathy, and arrhythmogenic right ventricular cardiomyopathy varies based on several factors including phenotype, type of exercise, guidelines referred to, and physicians’ own level of activity.

Keywords

Arrhythmiacardiomyopathyexercise restrictionβ-blocker therapy
Type
Original Articles
Information
Cardiology in the Young , Volume 26 , Issue 6 , August 2016 , pp. 1123 - 1129
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Copyright
© Cambridge University Press 2015 

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