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F-fluorodeoxyglucose-positive emission tomography/CT imaging for left ventricular assist device-associated infections in children

Published online by Cambridge University Press:  20 July 2018

Mohammed Absi*
Affiliation:
Departments of Pediatric Cardiology and Cardiothoracic Surgery, LeBonheur Children’s Medical Center, University of Tennessee Health Sciences Center, Memphis, TN, USA
Claire Bocchini
Affiliation:
Baylor College of Medicine, Houston, TX, USA
Jack F. Price
Affiliation:
Baylor College of Medicine, Houston, TX, USA
Iki Adachi
Affiliation:
Baylor College of Medicine, Houston, TX, USA
*
*Author for correspondence: M. Absi, Departments of Pediatric Cardiology and Cardiothoracic Surgery, LeBonheur Children’s Medical Center, University of Tennessee Health Sciences Center, 49 N Dunlap, Memphis, TN 38015, USA. Tel: 901-287-6380; Fax: 901-287-5970; E-mail: mabsi@uthsc.edu

Abstract

Left ventricular assist device implantation is an important therapeutic option for children with end-stage heart failure. However, device-related complications such as infection may occur while the patient is supported. Device-associated infection can be life-threatening, and early detection is critical. F-fluorodeoxyglucose positron emission tomography and CT is a highly sensitive imaging modality for the detection of an inflammatory response and is useful to evaluate the response to antibiotic therapy. We present two case reports of a left ventricular assist device-associated infection detected by F-fluorodeoxyglucose positron emission tomography and CT in children.

Type
Images in Congenital Cardiac Disease
Copyright
© Cambridge University Press 2018 

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References

1. Kim, J, Feller, ED, Chen, W, Dilsizian, V. FDG PET/CT imaging for LVAD associated infections. JACC Cardiovasc Imaging 2014; 7: 839842.Google Scholar
2. Tlili, G, Picard, F, Pinaquy, J, Domingues-Dos-Santos, P, Bordenave, L. The usefulness of FDG Pet/CT in suspicion of LVAD infection. J Nucl Cardiol 2014; 21: 845848.Google Scholar
3. Akin, S, Muslem, R, Constaninescu, AA, et al. 18F-FDG PET/CT in the diagnosis and management of continuous flow left ventricular assist device infections: a case series and review of the literature. ASAIO J, 2017 February 21 [Epub ahead of print].Google Scholar
4. Juneau, D, Golfam, M, Hazra, S, et al. Positron emission tomography and single-photon emission computed tomography imaging in the diagnosis of cardiac implantable electronic device infection: a systematic review and meta-analysis. Circ Cardiovasc Imaging 2017; 10: 111.Google Scholar
5. Dell’Aquilla, Am, Mastrobuoni, S, Alles, S, et al. Contributory role of fluorine 18-fluorodeoxyglucose positron emission tomography/computed tomography in the diagnosis and clinical management of infections in patients supported with a continuous-flow left ventricular assist device. Ann Thorac Surg 2016; 101: 8794.Google Scholar
6. Trachtenberg, BH, Cordero-Reyes, A, Elias, B, Loebe, M. A review of infections in patients with left ventricular assist devices: prevention, diagnosis and management. Methodist Debakey Cardiovasc J 2015; 11: 2832.Google Scholar