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Impact of platelet population behaviours in patients undergoing the Glenn procedure

Part of: Cardiac Morphology Functionally Univentricular Heart Hypoplastic Left Heart Syndrome (HLHS) Surgery

Published online by Cambridge University Press:  12 April 2021

Ergin Arslanoglu ,
Eylem Tuncer ,
Nihat Cine ,
Kenan Abdurrahman Kara Open the ORCID record for Kenan Abdurrahman Kara [Opens in a new window] ,
Babürhan Ozbek ,
Abdullah Arif Yılmaz ,
Fatih Tomrukcu ,
Omer Savluk Faruk ,
Fatma Ukil  and
Hakan Ceyran
Ergin Arslanoglu
Affiliation:
Pediatric Cardiovascular Surgery Department Kartal Kosuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey
Eylem Tuncer
Affiliation:
Pediatric Cardiovascular Surgery Department Kartal Kosuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey
Nihat Cine
Affiliation:
Pediatric Cardiovascular Surgery Department Kartal Kosuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey
Kenan Abdurrahman Kara*
Affiliation:
Pediatric Cardiovascular Surgery Department Kartal Kosuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey
Babürhan Ozbek
Affiliation:
Pediatric Cardiovascular Surgery Department Kartal Kosuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey
Abdullah Arif Yılmaz
Affiliation:
Pediatric Cardiovascular Surgery Department Kartal Kosuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey
Fatih Tomrukcu
Affiliation:
Pediatric Cardiovascular Surgery Department Kartal Kosuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey
Omer Savluk Faruk
Affiliation:
Anaesthesia and Reanimation Department Kartal Kosuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey
Fatma Ukil
Affiliation:
Anaesthesia and Reanimation Department Kartal Kosuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey
Hakan Ceyran
Affiliation:
Pediatric Cardiovascular Surgery Department Kartal Kosuyolu High Speciality Educational and Research Hospital, İstanbul, Turkey
*
Author for correspondence: Kenan Abdurrahman Kara, MD, Associate Professor, Pediatric Cardiovascular Surgery Department Kartal Koşuyolu High Speciality Educational and Research Hospital, Denizer street no:2 post code:34865 Kartal İstanbul, Turkey. Tel: +905300655225. E-mail: kenankaradoc@gmail.com
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Abstract

Pulmonary pressure is one of the most important parameters in the postoperative follow-up of patients who have undergone the Glenn procedure. Platelet activation markers, which are inexpensive and easily accessible blood count parameters, have been shown to be associated with the aetiology and pathogenesis of primary pulmonary artery hypertension. We examined the relationship between platelet activation markers and pulmonary pressures in the early postoperative period of patients who underwent the Glenn procedure.

Eighty-five patients who underwent the Glenn procedure in our clinic between January 2011 and March 2020 were included in the study retrospectively. Fifty-one patients were male and 34 were female, and age varied from 4 to 416 months, with a mean of 28.64 ± 51 months.

Patients with increased pulmonary blood flow on palliation before Glenn surgery had higher mean platelet volume values. However, no correlation was found between pulmonary pressures and platelet activation markers in the early postoperative period.

There was not similar study evaluating platelet activation markers in the paediatric age group before and after postoperative Glenn surgery in the literature. Therefore, even if platelet activation markers provide information about the pulmonary bed, they may be misleading due to other reasons that trigger bleeding and inflammatory processes in the early postoperative period.

Keywords

Congenital cardiac surgeryGlenn procedurepulmonary artery hypertensionmean platelet volumeplatelet distribution widthfunctionally univentricular heart
Type
Original Article
Information
Cardiology in the Young , Volume 31 , Issue 10 , October 2021 , pp. 1675 - 1679
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Copyright
© The Author(s), 2021. Published by Cambridge University Press

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