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Incidental detection of parvovirus myocarditis at time of resection of discrete subaortic stenosis

Published online by Cambridge University Press:  20 November 2006

Pui-Ying Iroh Tam ,
Karina Butler  and
Colin J. McMahon
Pui-Ying Iroh Tam
Affiliation:
Department of Paediatric Cardiology, Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland
Karina Butler
Affiliation:
Department of Infectious Disease, Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland
Colin J. McMahon
Affiliation:
Department of Paediatric Cardiology, Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland
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Abstract

We report an asymptomatic 18-month-old boy who underwent surgical resection of the discrete subaortic stenosis. Histopathologic examination of the muscle demonstrated diffuse lymphocytic infiltration of the myocardium. Polymerase chain reaction analysis of blood demonstrated parvovirus. This report highlights that asymptomatic myocarditis may be more prevalent than we realise, and that involvement of the myocardium by parvovirus may be entirely asymptomatic.

Keywords

Parvovirusmyocarditisviral infection of myocardium
Type
Brief Report
Information
Cardiology in the Young , Volume 16 , Issue 6 , December 2006 , pp. 596 - 598
Copyright
© 2006 Cambridge University Press

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References

Press S, Lipkind RS. Acute myocarditis in infants. Initial presentation. Clin Pediatr 1990; 29: 73–76.Google Scholar
O'Donnell WM, Mann RH. Asymptomatic giant cell granulomatous myocarditis. Am Heart J 1966; 72: 686–691.Google Scholar
Seshadri S, Narula J, Chopra P. Asymptomatic eosinophilic myocarditis: 2 + 2 = 5! Int J Cardiol 1991; 31: 348–349.Google Scholar
Bowles NE, Ni J, Kearney DL, Pauschinger M, et al. Detection of viruses in myocardial tissues by polymerase chain reaction: evidence of adenovirus as a common cause of myocarditis in children and adults. J Am Coll Cardiol 2003; 42: 466–472.Google Scholar
Bowles NE, Vallejo J. Viral causes of cardiac inflammation. Curr Opin Cardiol 2003; 18: 182–188.Google Scholar
Pankuweit S, Moll R, Baandrup U, Portig I, Hufnagel G, Maisch B. Prevalence of the parvovirus B19 genome in endomyocardial biopsy specimens. Hum Pathol 2003; 34: 497–503.Google Scholar
Schowengerdt KO, Ni J, Denfield SW, et al. Association of parvovirus B19 genome in children with myocarditis and cardiac allograft rejection: diagnosis using the polymerase chain reaction. Circulation 1997; 96: 3549–3554.Google Scholar
Bowles NE, Javier Fuentes-Garcia F, Makar KA, et al. Analysis of the coxsackievirus B-adenovirus receptor gene in patients with myocarditis or dilated cardiomyopathy. Mol Genet Metab 2002; 77: 257–259.Google Scholar
Murry CE, Jerome KR, Reichenbach DD. Fatal parvovirus myocarditis in a 5-year-old girl. Hum Pathol 2001; 32: 342–345.Google Scholar
English RF, Janosky JE, Ettedgui JA, Webber SA. Outcomes for children with acute myocarditis. Cardiol Young 2004; 14: 488–493.Google Scholar