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Midazolam for conscious sedation in transcatheter device closure of atrial septal defects guided solely by transthoracic echocardiography

Part of: Atrial Septal Defect (ASD) Interventional Cardiology

Published online by Cambridge University Press:  24 May 2021

Zeng-Chun Wang ,
Jian-Feng Liu ,
Yu-Qing Lei ,
Ning Xu ,
Shu-Ting Huang ,
Liang-Wan Chen ,
Hua Cao Open the ORCID record for Hua Cao [Opens in a new window]  and
Qiang Chen Open the ORCID record for Qiang Chen [Opens in a new window]
Zeng-Chun Wang
Affiliation:
Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China Fujian Key Laboratory of Women and Children’s Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, China Fujian Branch of Shanghai Children’s Medical Center, Fuzhou, China Fujian Children’s Hospital, Fuzhou, China Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou, China
Jian-Feng Liu
Affiliation:
Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China Fujian Key Laboratory of Women and Children’s Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, China Fujian Branch of Shanghai Children’s Medical Center, Fuzhou, China Fujian Children’s Hospital, Fuzhou, China
Yu-Qing Lei
Affiliation:
Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China Fujian Key Laboratory of Women and Children’s Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, China Fujian Branch of Shanghai Children’s Medical Center, Fuzhou, China Fujian Children’s Hospital, Fuzhou, China
Ning Xu
Affiliation:
Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China Fujian Key Laboratory of Women and Children’s Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, China Fujian Branch of Shanghai Children’s Medical Center, Fuzhou, China Fujian Children’s Hospital, Fuzhou, China
Shu-Ting Huang
Affiliation:
Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China Fujian Key Laboratory of Women and Children’s Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, China Fujian Branch of Shanghai Children’s Medical Center, Fuzhou, China Fujian Children’s Hospital, Fuzhou, China
Liang-Wan Chen
Affiliation:
Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou, China
Hua Cao
Affiliation:
Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China Fujian Key Laboratory of Women and Children’s Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, China Fujian Branch of Shanghai Children’s Medical Center, Fuzhou, China Fujian Children’s Hospital, Fuzhou, China
Qiang Chen*
Affiliation:
Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China Fujian Key Laboratory of Women and Children’s Critical Diseases Research, Fujian Maternity and Child Health Hospital, Fuzhou, China Fujian Branch of Shanghai Children’s Medical Center, Fuzhou, China Fujian Children’s Hospital, Fuzhou, China Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou, China
*
Author for correspondence: Qiang Chen, MD, Department of Cardiac Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, No. 18, Daoshan Road, Gulou District, Fuzhou350001, China.
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Abstract

Objectives:

To investigate the safety and feasibility of midazolam for conscious sedation in transcatheter device closure of atrial septal defects guided solely by transthoracic echocardiography.

Methods:

A retrospective analysis was performed on 55 patients who underwent transcatheter device closure of atrial septal defects from October, 2019 to May, 2020. All patients received intravenous midazolam and local anesthesia with lidocaine to maintain sedation. A group of previous patients with unpublished data who underwent the same procedure with general anesthesia was set as the control group. The relevant clinical parameters, the Ramsay sedation scores, the numerical rating scale, and the post-operative satisfaction questionnaire were recorded and analyzed.

Results:

In the midazolam group, the success rate of atrial septal defect closure was 98.2%. Hemodynamic stability was observed during the procedure. None of the patients needed additional endotracheal intubation for general anesthesia. Compared with the control group, the midazolam group had no statistically significant differences in the Ramsay sedation score and numerical rating scale scores. Patients in the midazolam group experienced more post-operative satisfaction than those in the control group.

Conclusions:

Conscious sedation using midazolam is a safe and effective anesthetic technique for transcatheter device closure of atrial septal defects guided solely by transthoracic echocardiography.

Keywords

midazolamsedationatrial septal defectsdevice
Type
Original Article
Information
Cardiology in the Young , Volume 32 , Issue 2 , February 2022 , pp. 282 - 286
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Copyright
© The Author(s), 2021. Published by Cambridge University Press

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Footnotes

*

These authors shared the corresponding authorship.

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