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Prognostic features in childhood idiopathic dilated cardiomyopathy

Published online by Cambridge University Press:  19 August 2008

Karen S. Rheuban ,
Donna Cregan-Lambert  and
Howard P. Gutgesell
Karen S. Rheuban*
Affiliation:
University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
Donna Cregan-Lambert
Affiliation:
University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
Howard P. Gutgesell
Affiliation:
University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
*
Karen S. Rheuban, M.D. University of Virginia Health Sciences Center, Divison of Pediatric Cardiology, Box 386. Charlottesville, Virginia 22908. Tel: 804-924-2481; Fax 804-982-1415
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Abstract

The clinical course, noninvasive findings and outcome of 25 infants and children with idiopathic dilated cardiomyopathy were reviewed retrospectively to identify factors predictive of outcome both at diagnosis and at short-term follow-up. Patients, stratified by clinical status at last visit, were assigned to groups encompassing those who were asymptomatic and receiving on medication, those patients who were symptomatic or needed medication to control symptoms, and those who were dead, awaiting heart transplantation, or had undergone transplantation. Older age at diagnosis was strongly associated with poor clinical outcome (p=0.005), as was the presence of arrhythmias at the time of diagnosis (p=0.008) and at short-term follow-up-(p=0.003). Echocardiographic studies at diagnosis failed to predict eventual clinical outcome, although patients who ultimately recovered and did not need medications tended to demonstrate improvement in or resolution of echocardiographic abnormalities within 6 months of diagnosis.

Keywords

dilated cardiomyopathyprognostic features
Type
Original Articles
Information
Cardiology in the Young , Volume 7 , Issue 2 , April 1997 , pp. 183 - 187
Copyright
Copyright © Cambridge University Press 1997

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