Hostname: page-component-cd9895bd7-dzt6s Total loading time: 0 Render date: 2024-12-26T04:24:48.319Z Has data issue: false hasContentIssue false
  • English
  • Français

Neurotic depression as the missing link: old wine with a new twist on anxiety and major depressive disorder

Published online by Cambridge University Press:  11 May 2015

A. A. Nierenberg  and
K. K. Ellard
A. A. Nierenberg*
Affiliation:
Bipolar Clinic and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston MA
K. K. Ellard
Affiliation:
Bipolar Clinic and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston MA
*
Address for correspondence: Andrew A. Nierenberg, MD, Bipolar Clinic and Research Program, Massachusetts General Hospital, Harvard Medical School, Suite 580, 50 Staniford Street, Boston MA 02114. (Email: anierenberg@mgh.harvard.edu)
Get access Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'

Keywords

NeurosisDepressionAnxietyEmotional Processing
Type
Commentaries to Special Article
Information
Epidemiology and Psychiatric Sciences , Volume 24 , Issue 3 , June 2015 , pp. 230 - 232
Copyright
Copyright © Cambridge University Press 2015 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Akers, KG, Martinez-Canabal, A, Restivo, L, Yiu, AP, De Cristofaro, A, Hsiang, H-LL, Wheeler, AL, Guskjolen, A, Niibori, Y, Shoji, H (2014). Hippocampal neurogenesis regulates forgetting during adulthood and infancy. Science 344, 598–602.Google Scholar
Barlow, DH, Ellard, KK, Sauer-Zavala, S, Bullis, JR, Carl, JR (2014 a). The origins of neuroticism. Perspectives on Psychological Science 9, 481–496.Google Scholar
Barlow, DH, Sauer-Zavala, S, Carl, JR, Bullis, JR, Ellard, KK (2014 b). The nature, diagnosis, and treatment of neuroticism back to the future. Clinical Psychological Science 2, 344–365.Google Scholar
Clelland, CD, Choi, M, Romberg, C, Clemenson, GD, Fragniere, A, Tyers, P, Jessberger, S, Saksida, LM, Barker, RA, Gage, FH (2009). A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science 325, 210–213.Google Scholar
Ellard, KK, Fairholme, CP, Boisseau, CL, Farchione, TJ, Barlow, DH (2010). Unified protocol for the transdiagnostic treatment of emotional disorders: protocol development and initial outcome data. Cognitive and Behavioral Practice 17, 88–101.Google Scholar
Farchione, TJ, Fairholme, CP, Ellard, KK, Boisseau, CL, Thompson-Hollands, J, Carl, JR, Gallagher, MW, Barlow, DH (2012). Unified protocol for transdiagnostic treatment of emotional disorders: a randomized controlled trial. Behavior Therapy 43, 666–678.Google Scholar
Harmer, CJ, Cowen, PJ (2013). ‘It's the way that you look at it’ – a cognitive neuropsychological account of SSRI action in depression. Philosophical Transactions of the Royal Society B: Biological Sciences 368, 20120407.Google Scholar
Holtzheimer, PE, Mayberg, HS (2011). Stuck in a rut: rethinking depression and its treatment. Trends in Neurosciences 34, 1–9.Google Scholar
Malberg, JE, Eisch, AJ, Nestler, EJ, Duman, RS (2000). Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. The Journal of Neuroscience 20, 9104–9110.Google Scholar
McCabe, C, Mishor, Z (2011). Antidepressant medications reduce subcortical cortical resting-state functional connectivity in healthy volunteers. NeuroImage 57, 1317–1323.Google Scholar
Milad, MR, Rosenbaum, BL, Simon, NM (2014). Neuroscience of fear extinction: implications for assessment and treatment of fear-based and anxiety related disorders. Behaviour Research and Therapy 62, 17–23.Google Scholar
Pessoa, L (2008). On the relationship between emotion and cognition. Nature Reviews Neuroscience 9, 148–158.Google Scholar
Sahay, A, Scobie, KN, Hill, AS, O'Carroll, CM, Kheirbek, MA, Burghardt, NS, Fenton, AA, Dranovsky, A, Hen, R (2011). Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation. Nature 472, 466–470.Google Scholar
Sen, S, Duman, R, Sanacora, G (2008). Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biological Ppsychiatry 64, 527–532.Google Scholar
Soskin, DP, Carl, JR, Alpert, J, Fava, M (2012). Antidepressant effects on emotional temperament: toward a biobehavioral research paradigm for major depressive disorder. CNS Neuroscience & Therapeutics, 18, 441–451.Google Scholar
Yassa, MA, Stark, CEL (2011). Pattern separation in the hippocampus. Trends in Neurosciences 34, 515–525.Google Scholar