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Loneliness, health and mortality

Published online by Cambridge University Press:  30 October 2017

J. Henriksen*
Affiliation:
Psychiatric Research Academy, Department of Affective Disorders, Aarhus University Hospital, Skovagervej 2, 8240 Risskov, Denmark
E. R. Larsen
Affiliation:
Department of Affective Disorders, Aarhus University Hospital, Skovagervej 2, 8240 Risskov, Denmark
C. Mattisson
Affiliation:
Department of Psychiatry, Institute of Clinical Sciences, The Lundby Study, Lund University Hospital, 221 85 Lund, Sweden
N. W. Andersson
Affiliation:
Department of Epidemiology Research, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark
*
*Address for correspondence: Jeppe Henriksen, Aarhus University Hospital, Skovagervej 2, 8240 Risskov, Denmark. (E-mail: jeppe_henriksen@hotmail.com)

Abstract

Aims.

Literature suggests an association between loneliness and mortality for both males and females. Yet, the linkage of loneliness to mortality is not thoroughly examined, and need to be replicated with a long follow-up time. This study assessed the association between loneliness and mortality, including associations to gender, in 1363 adult swedes.

Methods.

This community-based prospective cohort study from the Swedish Lundby Study included 1363 individuals of whom 296 individuals (21.7%) were identified as lonely with use of semi-structured interviews in 1997. The cohort was followed until 2011 and survival analyses were used to estimate the relative risk of death.

Results.

Death occurred with an incidence rate of 2.63 per 100 person-years and 2.09 per 100 person-years for lonely and non-lonely individuals, respectively. In crude analysis, loneliness was associated with a significant increased mortality risk of 27% compared with non-lonely individuals [hazard ratio (HR) 1.27; 95% CI 1.01–1.60]. Unadjusted, lonely females had a significant increased risk (HR 1.76; 95% CI 1.31–2.34) and adjusted insignificant increased mortality risk of 27% (HR 1.27; 95% CI 0.92–1.74), compared with non-lonely females. Lonely males were found to have an adjusted significant decreased risk of mortality (HR 0.50; 95% CI 0.32–0.80), compared with non-lonely males.

Conclusions.

Findings suggest an association between loneliness and increased risk of mortality and that gender differences may exist, which have not been previously reported. If replicated, our results indicate that loneliness may have differential physical implications in some subgroups. Future studies are needed to further investigate the influence of gender on the relationship.

Type
Original Articles
Copyright
Copyright © Cambridge University Press 2017 

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References

Christiansen, J, Larsen, FB, Lasgaard, M (2016). Do stress, health behavior, and sleep mediate the association between loneliness and adverse health conditions among older people? Social Science and Medicine 152, 8086.Google Scholar
de Jong-Gierveld, J (1987). Developing and testing a model of loneliness. Journal of Personality and Social Psychology 53, 119128.Google Scholar
Drageset, J, Eide, GE, Kirkevold, M, Ranhoff, AH (2013). Emotional loneliness is associated with mortality among mentally intact nursing home residents with and without cancer: a five-year follow-up study. Journal of Clinical Nursing 22, 106114.Google Scholar
Hawkley, LC, Cacioppo, JT (2002). Loneliness and pathways to disease. Brain, Behavior, and Immunity 17, 98105.Google Scholar
Hawkley, LC, Cacioppo, JT (2010). Loneliness matters: a theoretical and empirical review of consequences and mechanisms. Annals of Behavioral Medicine 40, 218227.Google Scholar
Hawkley, LC, Masi, CM, Berry, JD, Cacioppo, JT (2006). Loneliness is a unique predictor of age-related differences in systolic blood pressure. Psychological Aging 21, 152164.Google Scholar
Hawkley, LC, Thisted, RA, Masi, CM, Cacioppo, JT (2010). Loneliness predicts increased blood pressure: 5-year cross-lagged analyses in middle-aged and older adults. Psychological Aging 25, 132141.Google Scholar
Holt-Lunstad, J, Smith, TB, Baker, M, Harris, T, Stephenson, D (2015). Loneliness and social isolation as risk factors for mortality: a meta-analytic review. Perspectives on Psychological Science 10, 227237.Google Scholar
Holwerda, TJ, Beekman, AT, Deeg, DJ, Stek, ML, van Tilburg, TG, Visser, PJ, Schmand, B, Jonker, C, Schoevers, RA (2012). Increased risk of mortality associated with social isolation in older men: only when feeling lonely? Results from the Amsterdam Study of the Elderly (AMSTEL). Psychological Medicine 42, 843853.Google Scholar
Luanaigh, CO, Lawlor, BA (2008). Loneliness and the health of older people. International Journal of Geriatric Psychiatry 23, 12131221.Google Scholar
Luo, Y, Waite, LJ (2014). Loneliness and mortality among older adults in China. The Journals of Gerontology 69, 633645.Google Scholar
Luo, Y, Hawkley, LC, Waite, LJ, Cacioppo, JT (2012). Loneliness, health, and mortality in old age: a national longitudinal study. Social Science and Medicine 74, 907914.Google Scholar
Mattisson, C, Bogren, M, Horstmann, V (2013). Correspondence between clinical diagnoses of depressive and anxiety disorders and diagnostic screening via the Hopkins Symptom Check List-25 in the Lundby Study. Nordic Journal of Psychiatry 67, 204213.Google Scholar
Mattisson, C, Bogren, M, Bradvik, L, Horstmann, V (2015). Mortality of subjects with mood disorders in the Lundby community cohort: a follow-up over 50 years. Journal of Affective Disorders 178, 98106.Google Scholar
Momtaz, YA, Hamid, TA, Yusoff, S, Ibrahim, R, Chai, ST, Yahaya, N, Abdullah, SS (2012). Loneliness as a risk factor for hypertension in later life. Journal of Aging Health 24, 696710.Google Scholar
Newall, NE, Chipperfield, JG, Bailis, DS, Stewart, TL (2013). Consequences of loneliness on physical activity and mortality in older adults and the power of positive emotions. Health Psychology 32, 921924.Google Scholar
Patterson, AC, Veenstra, G (2010). Loneliness and risk of mortality: a longitudinal investigation in Alameda County, California. Social Science and Medicine 71, 181186.Google Scholar
Peplau, LA, Perlman, D (1982). Loneliness: A Sourcebook of Current Theory, Research, and Therapy. Wiley.Google Scholar
Perissinotto, CM, Stijacic Cenzer, I, Covinsky, KE (2012). Loneliness in older persons: a predictor of functional decline and death. Archives of Internal Medicine 172, 10781083.Google Scholar
Pinquart, M, Sorensen, S. (2003). Risk factors for loneliness in adulthood and old age: a meta-analysis. Advances in Psychology Research 19, 111143.Google Scholar
Russell, D, Peplau, LA, Ferguson, ML (1978). Developing a measure of loneliness. Journal of Personality Assessment 42, 290294.Google Scholar
Shiovitz-Ezra, S, Ayalon, L (2010). Situational versus chronic loneliness as risk factors for all-cause mortality. International Psychogeriatrics 22, 455462.Google Scholar
Stessman, J, Jacobs, JM, Iecovich, E (2011). Loneliness, social networks, and mortality: 18 years of follow-up. The International Journal of Aging and Human Development 72, 243263.Google Scholar
Stessman, J, Rottenberg, Y, Shimshilashvili, I, Ein-Mor, E, Jacobs, JM (2014). Loneliness, health, and longevity. Journal of Gerontology 69, 744750.Google Scholar
Swedish socio-economic Classification, SEI (1982). Reports on Statistical Coordination. 1982. Tech Rep 4, Statistics Sweden, Stockholm.Google Scholar
The Cause of Death Register (2004). Epidemiological Centre, National Board on Health and Welfare: Stockholm, Sweden.Google Scholar
Thurston, RC, Kubzansky, LD (2009). Women, loneliness, and incident coronary heart disease. Psychosomatic Medicine 71, 836842.Google Scholar
Tilvis, RS, Laitala, V, Routasalo, PE, Pitkala, KH (2011). Suffering from loneliness indicates significant mortality risk of older people. Journal of Aging Research 2011, 534781.Google Scholar
Whisman, MA (2010). Loneliness and the metabolic syndrome in a population-based sample of middle-aged and older adults. Health Psychology 29, 550554.Google Scholar