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Los efectos de la trazodona sobre las perturbaciones del sueño inducidas por brofaromina

Published online by Cambridge University Press:  12 May 2020

P.M.J. Haffmans  and
M.S. Vos
P.M.J. Haffmans
Affiliation:
Stichting BBC, location Monsterseweg, La Haya, Holanda
M.S. Vos
Affiliation:
Stichting BBC, location Monsterseweg, La Haya, Holanda
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Resumen

Se compararon los efectos de la trazodona sobre los parámetros subjetivos y objetivos del sueño con los del placebo en un diseño doble ciego en siete pacientes que desarrollaron insomnio durante el tratamiento con el inhibidor selectivo y reversible de la MAO-A brofaromina. La trazodona aumentó significativamente el sueño profundo y alteró la arquitectura del sueño en estos pacientes. Subjetivamente, éstos comunicaron un sueño mejor y más profundo. No se observaron interacciones negativas entre la brofaromina y la trazodona, y los efectos secundarios fueron mínimos. Una dosis baja de trazodona puede ser un agente seguro y efectivo en el tratamiento del insomnio inducido por inhibidores de la MAO.

Keywords

depresióninsomnioinhibidor de la MAOtrazodona
Type
Comunicación breve
Information
European Psychiatry (Ed. Española) , Volume 7 , Issue 2 , March 2000 , pp. 114 - 118
Copyright
Copyright © European Psychiatric Association 2000

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Footnotes

Haffmans PMJ, Vos MS. The effects of trazodone on sleep disturbances induced by brofaromine. Eur Psychiatry 1999; 14: 167-71.

References

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