In a short-term competition experiment in large containers, growth of cotton planted 3 weeks after bermudagrass (Cynodon dactylon), johnsongrass (Sorghum halepense) or purple nutsedge (Cyperus rotundus), was severely reduced; after 10 weeks of competition, weedy cotton weighed only 15 per cent of the weed-free control. Cotton sown before weeds, or weeds planted before cotton, were only slightly affected by competition. Highly significant negative correlations were found between growth parameters of cotton and weeds. Inhibiting effects, and in some cases transitory stimulation, were produced on mustard seedlings by leachate from weed-infested soil and by extracts from subterranean weed parts, suggesting that the competitive effects of perennial weeds are due to nutrient depletion and to biologically active substances.