Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-26T05:06:55.193Z Has data issue: false hasContentIssue false
  • English
  • Français

Onchocerca volvulus infections in chimpanzees: an assessment of the requirements for vaccination trials

Published online by Cambridge University Press:  05 June 2009

Mark J. Taylor
Mark J. Taylor
Affiliation:
Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK
Get access Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Review Article
Information
Journal of Helminthology , Volume 68 , Issue 1 , March 1994 , pp. 3 - 6
Copyright
Copyright © Cambridge University Press 1994

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Abraham, D., Eberhard, M.L., Lange, A.M., Yutanawiboonchai, W., Perler, F.B. & Lok, J.B. (1992) Identification of surrogate rodent hosts for larval Onchocerca lienalis and induction of protective immunity in a model system. Journal of Parasitology 78, 447–453.CrossRefGoogle ScholarPubMed
Bianco, A.E. (1991) Onchocerciasis – river blindness. pp. 138–203 in Macpherson, C.M.L. & Craig, P.S. (Eds) Parasitic worms, zoonoses and human health in Africa. London, Unwin Hayman Press.Google Scholar
Bianco, A.E., Ham, P.J., Townson, S., Mustafa, M.B. & Nelson, G.S. (1989) A semi-automated system of intrathoracic injection for the large-scale production of Onchocerca lienalis infective larvae. Tropical Medicine and Parasitology 40, 57–64.Google ScholarPubMed
Duke, B.O.L. (1962) Experimental transmission of Onchocerca volvulus from man to a chimpanzee. Transactions of the Royal Society of Tropical Medicine and Hygiene 56, 271.Google Scholar
Duke, B.O.L. (1980) Observations on Onchocerca volvulus in experimentally infected chimpanzees. Tropical Medicine and Parasitology 31, 41–54.Google ScholarPubMed
Eberhard, M.L., Dickerson, J.W., Boyer, A.E., Tsang, V.C.W., Zea-Flores, R., Walker, E.M., Richards, F.O., Zea-Flores, G. & Strobert, E. (1991) Experimental Onchocerca volvulus infections in mangabey monkeys (Cercocebus atys) compared to infections in humans and chimpanzees (Pan troglodytes). American Journal of Tropical Medicine and Hygiene 44, 151–160.CrossRefGoogle ScholarPubMed
Greene, B.M. (1987) Primate model for onchocerciasis research. pp. 236–243 in Filariasis. Chichester, Wiley (Ciba Foundation Symposium 127).Google Scholar
Johnson, E.H., Lustigman, S., Brotman, B., Browne, J. & Prince, A.M. (1991) Onchocerca volvulus: in vitro killing of microfilaria by neutrophils and eosinophils from experimentally infected chimpanzees. Tropical Medicine and Parasitology 42, 351–355.Google ScholarPubMed
Luder, C.G.K., Soboslay, P.T., Prince, A.M., Greene, B.M., Lucius, R. & Schulz-Key, H. (1993) Experimental onchocerciasis in chimpanzees: cellular responses and antigen recognition after immunization and challenge with Onchocerca volvulus infective third-stage larvae. Parasitology 107, 87–97.CrossRefGoogle ScholarPubMed
Neumann, E., Lucassa, C. & Gunders, A. (1964) Experimental onchocercal ocular lesions in the chimpanzee. American Journal of Ophthalmology 57, 217–227.CrossRefGoogle ScholarPubMed
Prince, A.M., Brotman, B., Johnson, E.H., Smith, A., Pascual, D. & Lustigman, S. (1992) Onchocerca volvulus: immunization of chimpanzees with X-irradiated third-stage larvae. Experimental Parasitology 74, 239–250.CrossRefGoogle Scholar
Soboslay, P.T., Dreweck, C.M., Taylor, H.R., Brotman, B., Wenk, P. & Greene, B.M. (1991) Experimental onchocerciasis in chimpanzees. Cell-mediated immune responses, and production and effects of IL-1 and IL-2 with Onchocerca volvulus infection. Journal of Immunology 147, 346–353.CrossRefGoogle ScholarPubMed
Soboslay, P.T., Weiss, N., Dreweck, C.M., Taylor, H.R., Brotman, B., Schulz-Key, H. & Greene, B.M. (1992) Experimental onchocerciasis in chimpanzees, antibody response and antigen recognition after primary infection with Onchocerca volvulus. Experimental Parasitology 74, 367–380.CrossRefGoogle ScholarPubMed
Taylor, H.R., Trpis, M., Cupp, E.W., Brotman, B., Newland, H.S., Soboslay, P.T. & Greene, B.M. (1988) Ivermectin prophylaxis against experimental Onchocerca volvulus infection in chimpanzees. Americal Journal of Tropical Medicine and Hygiene 39, 86–90.CrossRefGoogle ScholarPubMed
Taylor, M.J., Van Es, R.P., Shay, K., Folkard, S.G., Townson, S. & Bianco, A.E. (1994) Protective immunity against Onchocerca volvulus and O. lienalis infective larvae in mice. Tropical Medicine and Parasitology 45, In press.Google Scholar
Weiss, N., Van Den Ende, M.C., Albiez, E.J., Barbiero, V.K., Forsyth, K. & Prince, A.M. (1986) Detection of serum antibodies and circulating antigens in a chimpanzee experimentally infected with Onchocerca volvulus. Transactions of the Royal Society of Tropical Medicine and Hygiene 80, 587–591.CrossRefGoogle Scholar