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Elucidating effective ways to identify and treat malnutrition

Published online by Cambridge University Press:  07 March 2007

Rebecca J. Stratton
Affiliation:
Institute of Human Nutrition, School of Medicine, University of Southampton,Southampton General Hospital, Southampton, SO16 6YD, UK
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Abstract

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There is a clear rationale for elucidating effective ways of identifying and treating disease-related malnutrition (DRM), given the physiological and financial consequences of this common condition and its treatability. Evidence indicates the efficacy of nutritional support methods (oral, tube and intravenous) in increasing total nutritional intake while having little effect on appetite, satiety, appetite mediators (e.g. leptin) and voluntary food intake. When used as the only source of nutrition, artificial nutrition can effectively maintain nutritional intake, and yet many patients find enteral or parenteral feeding alone is unable to relieve distressing appetite sensations, and unusual temporal patterns (including dissociation between hunger and desire to eat) occur. Despite the positive impact of these feeding methods on intake, controversy about whether nutritional support can affect patient outcome has remained. Systematic reviews and meta-analyses indicate that improvements in function and clinical (mortality, complication rates) outcome can occur in a number of patient groups (including hospitalised patients, the elderly, patients who have had gastrointestinal surgery, patients at risk of pressure ulcers). In order to target those patients who will benefit from nutritional support, and overcome the ongoing problem of poor detection and recognition of DRM, simple routine screening to identify risk followed by practical evidence-based treatment is recommended.

Type
Sir David Cuthbertson Medal Lecture
Copyright
Copyright © The Nutrition Society 2005

References

Blundell, JE (1979) Hunger, appetite and satiety – constructs in search of identities. In Nutrition and Lifestyles, pp. 2142 [Turner, M, editor]. London: Applied Science Publishers.Google Scholar
British Dietetic Association (1999) Nutrition Screening Tools. Professional Development Committee Briefing Paper no. 9. Birmingham: British Dietetic Association.Google Scholar
Council of Europe (2002) Food and Nutritional Care in Hospitals: How to Prevent Undernutrition. Report and Recommendations of the Committee of Experts on Nutrition, Food Safety and Consumer Protection. Strasbourg: Council of Europe.Google Scholar
Department of Health Department of Health (2001a) Essence of Care – Patient Focused Benchmarking for Healthcare Practitioners London: Department of HealthGoogle Scholar
Department of Health Department of Health (2001b) National Service Framework for Older People London: Department of HealthGoogle Scholar
Department of Health Department of Health (2003) Prescription Cost Analysis: England 2003 London: Department of Health www.publications.doh.gov.uk/stats/pca 2003 Google Scholar
Department of Health Department of Health (1998) Clinical Effectiveness Reference Pack London: Department of HealthGoogle Scholar
Elia, M (2003) Screening for Malnutrition: A Multidisciplinary Responsibility. Development and Use of the Malnutrition Universal Screening Tool (‘MUST’) for Adults Redditch, Worcs BAPENGoogle Scholar
Elia, M, Pang, F, Russell, C, Green, C & Stratton, RJ (2005) The Cost of Malnutrition in the UK and the Economic Case for Oral Nutritional Supplementation (ONS) in Adults Redditch, Worcs BAPEN In the PressGoogle Scholar
Elia, M & Stratton, RJ (2005) Nutritional support in the home setting. In Encyclopaedia of Human Nutrition [Caballero, B, Allen, L, editors]. Prentice A Oxford: Elsevier In the Press.Google Scholar
Gibney, E, Elia, M, Jebb, SA, Murgatroyd, PR & Jennings, G (1997) Total energy expenditure in patients with small-cell lung cancer: results of a validated study using the bicarbonate-urea method. Metabolism 46, 14121417 Google Scholar
Jebb, SA (1997) Energy metabolism in cancer and human immunodeficiency virus infection. Proceedings of the Nutrition Society 56, 763775 Google Scholar
King, CL, Elia, M, Stroud, MA & Stratton, RJ (2003) The predictive validity of the malnutrition universal screening tool (MUST) with regard to mortality and length of stay in elderly inpatients. Clinical Nutrition 22 S4 Google Scholar
Kondrup, J, Allison, SP, Elia, M, Vellas, B & Plauth, M (2003) ESPEN guidelines for nutrition screening 2002. Clinical Nutrition 22, 415421 Google Scholar
Landis, JR & Koch, GG (1977) The measurement of observer agreement for categorical data. Biometrics 33, 159174 CrossRefGoogle ScholarPubMed
Lewis, SJ, Egger, M, Sylvester, PA & Thomas, S (2001) Early enteral feeding versus ‘nil by mouth’ after gastrointestinal surgery: systematic review and meta-analysis of controlled trials. British Medical Journal 323, 773776 CrossRefGoogle ScholarPubMed
McWhirter, JP & Pennington, CR (1994) Incidence and recognition of malnutrition in hospital. British Medical Journal 308, 945948 Google Scholar
Milne, AC, Potter, J & Avenell, A (2002) Protein and Energy Supplementation in Elderly People at Risk from Malnutrition Oxford Cochrane Update SoftwareGoogle Scholar
Plata-Salaman, C (1996) Anorexia during acute and chronic disease. Nutrition 12, 6978 Google Scholar
Royal College of General Practitioners Clinical, Guidelines Working Group (1995) The Development and Implementation of Guidelines. Report from General Practice 26. London: Royal College of General Practitioners Google Scholar
Royal College, of Physicians (2002) Nutrition and Patients. A Doctor's Responsibility. Report of a Working Party of the Royal College of Physicians. London: Royal College of Physicians.Google Scholar
Scottish Intercollegiate, Guideline Network (1999) SIGN Guidelines: An Introduction to SIGN Methodology for the Development of Evidence-based Clinical Guidelines Edinburgh SIGNGoogle Scholar
Shekelle, PG, Woolf, SH, Eccles, M & Grimshaw, J (1999) Clinical guidelines: developing guidelines. British Medical Journal 18, 593596 Google Scholar
Stratton, RJ (1999) Artificial nutrition, appetite and food intake in health and disease. PhD Thesis, University of Cambridge.Google Scholar
Stratton, RJ, Dewit, O, Crowe, E, Jennings, G, Villar, RN & Elia, M (1997) Plasma leptin, energy intake and hunger following total hip replacement surgery. Clinical Science 93, 113117 Google Scholar
Stratton, RJ, Dixon, R, Longmore, D, Stroud, M & Elia, M (2003a) Effect of recalled weight and height on malnutrition risk. Clinical Nutrition 22, S910 Google Scholar
Stratton, RJ, Ek, A-C, Engfer, M, Moore, Z, Rigby, P, Wolfe, R & Elia, M (2005) Enteral nutritional support in prevention and treatment of pressure ulcers: a systematic review and meta-analysis Ageing Research Reviews.Google Scholar
Stratton, RJ & Elia, M (1999a) A critical, systematic analysis of the use of oral nutritional supplements in the community. Clinical Nutrition 18, 2984 Google Scholar
Stratton, RJ & Elia, M (1999b) The effects of enteral tube feeding and parenteral nutrition on appetite sensations and food intake in health and disease. Clinical Nutrition 18, 6370 Google Scholar
Stratton, RJ & Elia, M (2005) Meta-analysis suggests post-operative enteral nutritional support reduces complication rates in patients undergoing gastrointestinal surgery. Proceedings of the Nutrition Society 64 In the PressGoogle Scholar
Stratton, RJ, Green, CJ & Elia, M (2003b) Disease-related Malnutrition: An Evidence Based Approach to Treatment Wallingford, Oxon Published on behalf of The Nutrition Society by CABI PublishingGoogle Scholar
Stratton, RJ, Green, CJ & Elia, M (2004a) Simple cost analysis of changes in hospital length of stay with oral nutritional supplements from randomised controlled trials. Clinical Nutrition 23, 906907 Google Scholar
Stratton, RJ, Hackston, A, Longmore, D, Dixon, R, Price, S, Stroud, M, King, C & Elia, M (2004b) Malnutrition in hospital outpatients and inpatients: prevalence, concurrent validity and ease of use of the ‘Malnutrition Universal Screening Tool’ (‘MUST’) for adults. British Journal of Nutrition 92, 799808 Google Scholar
Stratton, RJ, King, C, Stubbs, S, Wood, C, Stroud, M & Elia, M (2004c) Cost of disease-related malnutrition in hospital according to ‘MUST’ and specialty. Clinical Nutrition 23, 918 Google Scholar
Stratton, RJ, Nugent, A & Elia, M (1999a) The value of modified sham feeding as a model to study pre-absorptive changes in appetite sensations. Proceedings of the Nutrition Society 58 126AGoogle Scholar
Stratton, RJ, Nugent, A, Rutgers, C & Elia, M (1999b) The effect of chewing nutritive and non-nutritive material (modified sham feeding model) on subsequent appetite sensations and food intake. Proceedings of the Nutrition Society 58 20AGoogle Scholar
Stratton, RJ, Stubbs, RJ, Cole, TJ & Elia, M (1998a) Impact of bolus feeding via nasogastric tube on appetite and food intake in humans. Clinical Nutrition 17, 3 CrossRefGoogle Scholar
Stratton, RJ, Stubbs, RJ & Elia, M (1998b) Inter-relationship between circulating leptin concentrations, hunger and energy intake in healthy subjects receiving tube feeding. Journal of Parenteral and Enteral Nutrition 22, 335339 CrossRefGoogle Scholar
Stratton, RJ, Stubbs, RJ & Elia, M (2000) Impact of nasogastric feeding duration on appetite and food intake. Clinical Nutrition 19, 54 Google Scholar
Stratton, RJ, Stubbs, RJ & Elia, M (2003c) Short-term continuous enteral tube feeding schedules do not suppress appetite and food intake in healthy men in a placebo-controlled trial. Journal of Nutrition 133, 25702576 Google Scholar
Stratton, RJ, Thompson, RL, Margetts, BM, Stroud, M, Jackson, AA & Elia, M (2002) Health care utilisation according to malnutrition risk in the elderly: an analysis of data from the National Diet and Nutrition Survey. Proceedings of the Nutrition Society 61 20AGoogle Scholar
Stubbs, RJ (1999) Peripheral signals affecting food intake. Nutrition 15, 614625 Google Scholar
Wood, C, Stubbs, S, Warwick, H, Dunnachie, A, Elia, M & Stratton, RJ (2004) Malnutrition risk and health care utilisation in orthopaedic patients. Proceedings of the Nutrition Society 63 20AGoogle Scholar