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Regulation of lumen fat digestion: enzymic aspects

Published online by Cambridge University Press:  11 October 2007

Robert Verger ,
Mustapha Aoubala ,
Frédéric Carrière ,
Stéphane Ransac ,
Liliane Dupuis ,
Josiane De Caro ,
Francine Ferrato ,
Isabelle Douchet ,
René Laugier  and
Alain De Caro
Robert Verger
Affiliation:
UPR 9025, Laboratoire de Lipolyse Enzymatique, IFRC1 du CNRS 31 Chemin Joseph-Aiguier, 13402 Marseille Cedex 20, France
Mustapha Aoubala
Affiliation:
UPR 9025, Laboratoire de Lipolyse Enzymatique, IFRC1 du CNRS 31 Chemin Joseph-Aiguier, 13402 Marseille Cedex 20, France
Frédéric Carrière
Affiliation:
UPR 9025, Laboratoire de Lipolyse Enzymatique, IFRC1 du CNRS 31 Chemin Joseph-Aiguier, 13402 Marseille Cedex 20, France
Stéphane Ransac
Affiliation:
UPR 9025, Laboratoire de Lipolyse Enzymatique, IFRC1 du CNRS 31 Chemin Joseph-Aiguier, 13402 Marseille Cedex 20, France
Liliane Dupuis
Affiliation:
UPR 9025, Laboratoire de Lipolyse Enzymatique, IFRC1 du CNRS 31 Chemin Joseph-Aiguier, 13402 Marseille Cedex 20, France
Josiane De Caro
Affiliation:
UPR 9025, Laboratoire de Lipolyse Enzymatique, IFRC1 du CNRS 31 Chemin Joseph-Aiguier, 13402 Marseille Cedex 20, France
Francine Ferrato
Affiliation:
UPR 9025, Laboratoire de Lipolyse Enzymatique, IFRC1 du CNRS 31 Chemin Joseph-Aiguier, 13402 Marseille Cedex 20, France
Isabelle Douchet
Affiliation:
UPR 9025, Laboratoire de Lipolyse Enzymatique, IFRC1 du CNRS 31 Chemin Joseph-Aiguier, 13402 Marseille Cedex 20, France
René Laugier
Affiliation:
UPR 9025, Laboratoire de Lipolyse Enzymatique, IFRC1 du CNRS 31 Chemin Joseph-Aiguier, 13402 Marseille Cedex 20, France
Alain De Caro
Affiliation:
UPR 9025, Laboratoire de Lipolyse Enzymatique, IFRC1 du CNRS 31 Chemin Joseph-Aiguier, 13402 Marseille Cedex 20, France
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Abstract

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Type
Principal Symposium on ‘Lipid absorption and metabolism: physiological and molecular aspects’
Information
Proceedings of the Nutrition Society , Volume 55 , Issue 1B , March 1996 , pp. 5 - 18
Copyright
Copyright © The Nutrition Society 1996

References

Anderson, R. A. & Sando, G. N. (1991). Cloning and expression of cDNA encoding human lysosomal acid lipase/cholesteryl ester hydrolase. Similarities to gastric and lingual lipases. Journal of Biological Chemistry 266, 22479–22484.CrossRefGoogle ScholarPubMed
Aoubala, M., Bonicel, J., Bénicourt, C., Verger, R. & de Caro, A. (1994). Tryptic cleavage of gastric lipases: Location of the single disulfide bridge. Biochimica et Biophysica Acta 1213, 319–324.CrossRefGoogle ScholarPubMed
Aoubala, M., Daniel, C., de Caro, A., Ivanova, M. G., Hirn, M., Sarda, L. & Verger, R. (1993a). Epitope mapping and immunoinactivation of human gastric lipase using five monoclonal antibodies. European Journal of Biochemistry 211, 99–104.CrossRefGoogle ScholarPubMed
Aoubala, M., Douchet, I., Laugier, R., Hirn, M., Verger, R. & de Caro, A. (1996). Purification of human gastric lipase by immunoaffinity and quantification of this enzyme in the duodenal contents using a new ELISA procedure. Biochimica et Biophysica Acta 1169, 183–188.CrossRefGoogle Scholar
Aoubala, M., Ivanova, M., Douchet, I., de Caro, A. & Verger, R. (1995). Interfacial binding of Human Gastric Lipase to lipid monolayers, measured with an ELISA. Biochemistry 34, 10786–10793.CrossRefGoogle ScholarPubMed
Bénicourt, C., Blanchard, C., Carrière, F., Verger, R., Junien, J.-L. (1993). Potential use of a recombinant dog gastric lipase as an enzymatic supplement to pancreatic extracts in cystic fibrosis. In Clinical Ecology of Cystic Fibrosis. 291–295 Escobar, H., Baquero, C. F., Suárez, L. Amsterdam: Elsevier Science Publishers B. V..Google Scholar
Bernbäck, S., Bläckberg, L. & Hernell, O. (1989). Fatty acids generated by gastric lipase promote human milk triacylglycerol digestion by pancreatic colipase-dependent lipase Biochimica el Biophysica Acta 1001, 286–291.CrossRefGoogle ScholarPubMed
Bernbäck, S., Hernell, O., Bläckberg, L. (1985). Purification and molecular characterization of bovine pregastric lipase. European Journal of Biochemistry 148, 233.CrossRefGoogle ScholarPubMed
Blow, D. M. (1971). The structure of chymotrypsin. In The Enzymes. vol. 3, 185–212 Boyer, P. D. New York and London: Academic Press.Google Scholar
Bodmer, M. W., Angal, S., Yarranton, G. T., Harris, T. J. R., Lyons, A., King, D. L., Piéroni, G., Rivière, C., Verger, R. & Lowe, P. A. (1987). Molecular cloning of a human gastric lipase and expression of the enzyme in yeast. Biochimica et Biophysica Acta 909, 237–244.CrossRefGoogle ScholarPubMed
Borgström, B. (1980). The importance of phospholipids, pancieatic phospholipase A2 and fatty acid for the digestion of dietary fat. Gastroenterology 78, 954–962.CrossRefGoogle ScholarPubMed
Bousset-Risso, M., Bonicel, J. & Rovery, M. (1985). Limited proteolysis of porcine pancreatic lipase. FEBS Letters 182, 323–326.CrossRefGoogle ScholarPubMed
Carrière, F., Barrowman, J. A., Verger, R. & Laugier, R. (1993). Secretion and contribution to lipolysis of gastric and pancreatic lipases during a test meal in humans. Gastroenterology 105, 876–888.CrossRefGoogle ScholarPubMed
Carrière, F., Gargouri, Y., Moreau, H., Ransac, S., Rogalska, E. & Verger, R. (1994). Gastric lipases: Cellular, biochemical and kinetic aspects. In Lipases: Their Structure, Biochemistry and Application. 181–205 Wooley, P. & Petersen, S. B. Cambridge: Cambridge University Press.Google Scholar
Carrière, F., Moreau, H., Raphel, V., Laugier, R., Bénicourt, C., Junien, J.-L. & Verger, R. (1991). Purification and biochemical characterization of dog gastric lipase. European Journal of Biochemistry 202, 75–83.CrossRefGoogle ScholarPubMed
Chapus, C., Sérémiva, M. (1976). Mechanism of pancreatic lipase action. 2. Catalytic properties of modified lipases. Biochemistry 15, 4988–4991.CrossRefGoogle ScholarPubMed
de Caro, J., Ferrato, F., Verger, R. & de Caro, A. (1995). Purification and molecular characterization of lamb pregastric lipase. Biochimica et Biophysica Acta 1252, 321–329.CrossRefGoogle ScholarPubMed
de Nigris, S. J., Hamosh, M., Kasbedar, D. K., Lee, T. C. & Hamosh, P. (1988). Lingual and gastric lipases: Species differences in the origin of prepancreatic digestive lipases and in the localization of gastric lipase. Biochimica et Biophysica Acta 958, 38–45.CrossRefGoogle Scholar
Derewenda, Z. S. & Cambillau, C. (1991). Effects of gene mutations in lipoprotein and hepatic lipases as interpreted by a molecular model of the pancreatic triglyceride lipase. Journal of Biological Chemistry 266, 23112–23119.CrossRefGoogle ScholarPubMed
Derewenda, Z. S. & Sharp, A. M. (1993). News from the interface: the molecular structures of triacylglyceride lipases. Trends in Biochemical Sciences 18, 20–25.CrossRefGoogle ScholarPubMed
Docherty, A. J. P., Bodmer, M. W., Angal, S., Verger, R., Rivière, C., Lowe, P. A., Lyons, A., Emtage, J. S. & Harris, T. J. R. (1985). Molecular cloning and nucleotide sequence of rat lingual lipase cDNA. Nucleic Acid Research 13, 1891–1903.CrossRefGoogle ScholarPubMed
Egloff, M.-P., Marguet, F., Buono, G., Verger, R., Cambillau, C. & van Tilbeurgh, H. (1995). The 2.46 Å resolution structure of the pancreatic lipase-colipase complex inhibited by a Cll alkyl phosphonate. Biochemistry 34, 2751–2762.CrossRefGoogle Scholar
Field, R. & Scow, R. O. (1983). Purification and characterization of rat lingual lipase. Journal of Biological Chemistry 258, 14563–14569.CrossRefGoogle ScholarPubMed
Gargouri, Y., Chahinian, H., Moreau, H., Ransac, S. & Verger, R. (1991). Inactivation of pancreatic and gastric lipases by THL and C12:0-TNB: a kinetic study with emulsified tributyrin. Biochimica et Biophysica Acta 1085, 322–328.CrossRefGoogle ScholarPubMed
Gargouri, Y., Moreau, H., Piéroni, G. & Verger, R. (1988). Human gastric lipase: A sulfhydryl enzyme. Journal of Biological Chemistry 263, 2159–2162.CrossRefGoogle ScholarPubMed
Gargouri, Y., Moreau, H. & Verger, R. (1989). Gastric lipases: Biochemical and physiological studies. Biochimica et Biophysica Acta 1006, 255–271.CrossRefGoogle ScholarPubMed
Gargouri, Y., Piéroni, G., Rivière, C., Lowe, P. A., Saunière, J.-F., Sarda, L. & Verger, R. (1986). Importance of human gastric lipase for intestinal lipolysis: An in vitro study. Biochimica et Biophysica Acta 879, 419–423.CrossRefGoogle ScholarPubMed
Guidoni, A., Benkouka, F., de Caro, J. & Rovery, M. (1981). Characterization of the serine reacting with diethyl p-nitrophenylphosphate in porcine pancreatic lipase. Biochlmica et Biophysica Acta 660, 148–150.CrossRefGoogle Scholar
Hamosh, M. (1984). Lingual lipase. In Lipases. 49–81 Borgström, B. & Brockman, H. L. Amsterdam: Elsevier.Google Scholar
Hamosh, M., Ganot, D. & Hamosh, P. (1979). Rat lingual lipase: Characteristics of enzyme activity. Journal of Biological Chemistry 254, 12121–12125.CrossRefGoogle ScholarPubMed
Hide, W. A., Chan, L. & Li, W. H. (1992). Structure and evolution of the lipase superfamily. Journal of Lipid Research 33, 167–178.CrossRefGoogle ScholarPubMed
Hull, M. & Keaton, R. W. (1917). The existence of a gastric lipase. Journal of Biological Chemistry 32, 127–140.CrossRefGoogle Scholar
Ivanova, M. G., Aoubala, M., de Caro, A., Daniel, C., Hirn, J. & Verger, R. (1993). A study on human gastric lipase and complexes with monoclonal antibodies using the monomolecular film technique. Colloids and Surfaces B 1, 17–22.CrossRefGoogle Scholar
Kirchgessner, T. G., Chuat, J. C., Heinzmann, C., Etienne, J., Guilhot, S., Svenson, K., Ameis, D., Pilon, C., d'Auriol, L., Andalibi, A., Schotz, M. C., Galibert, F. & Lusis, A. J. (1989). Organization of the human lipoprotein lipase gene and evolution of the lipase gene family. Proceedings of the National Academy of Sciences, USA 86, 9647–9651.CrossRefGoogle ScholarPubMed
Lohse, P., Lohse, P. & Seidel, D. (1995). Human lysosomal acid lipase: Functional analysis of the putative lid structure covering the active site Proceedings of the American Heart Association. 68th Scientific session Anaheim, California: Mosby.Google Scholar
Lüthi-Peng, Q. & Winkler, F. K. (1992). Large spectral changes accompany the conformational transition of human pancreatic lipase induced by acylation with the inhibitor tetrahydrolipstatin. European Journal of Biochemistry 205, 383–390.CrossRefGoogle ScholarPubMed
Moreau, H., Abergel, C., Carrière, F., Ferrato, F., Fontecilla-Camps, J. C., Cambillau, C. & Verger, R. (1992). Isoform purification of gastric lipases. Towards crystallization. Journal of Molecular Biology 225, 147–153.CrossRefGoogle ScholarPubMed
Moreau, H., Gargouri, Y., Lecat, D., Junien, J.-L. & Verger, R. (1988a). Screening of preduodenal lipases in several mammals. Biochimica et Biophysica Acta 959, 247–252.CrossRefGoogle ScholarPubMed
Moreau, H., Gargouri, Y., Lecat, D., Junien, J.-L. & Verger, R. (1988b). Purification, characterization and kinetic properties of the rabbit gastric lipase. Biochimica et Biophysica Acta 960, 286–293.CrossRefGoogle ScholarPubMed
Moreau, H., Gargouri, Y., Piéroni, G. & Verger, R. (1988c). Importance of sulfhydryl group for rabbit gastric lipase activity. FEES Letters 236, 383–387.CrossRefGoogle ScholarPubMed
Moreau, H., Moulin, A., Gargouri, Y., Noël, J.-P. & Verger, R. (1991). Inactivation of gastric and pancreatic lipases by diethyl p-nitrophenyl phosphate. Biochemistry 30, 1037–1041.CrossRefGoogle ScholarPubMed
Mossi, S., Aoubala, M., de Caro, A., Verger, R. & Laugier, R. (1994). Gastric lipase (GL) becomes essential for the lipid digestion during severe pancreatic exocrine insufficiency (PEI). Digestion 55, 328.Google Scholar
Ollis, D. L., Cheah, E., Cygler, M., Dijkstra, B., Frolow, F., Franken, S. M., Harel, M., Remington, S. J., Silman, I., Schrag, J., Sussman, J. L., Verschueren, K. H. G. & Goldman, A. (1992). The α/β hydrolase fold. Protein Engineering 5, 197–211.CrossRefGoogle ScholarPubMed
Persson, B., Bentsson-Olivecrona, G., Enerbäck, S., Olivecrona, T., Jörnvall, H. (1989). Structural features of lipoprotein lipase. Lipase family relationships, binding interactions, non-equivalence of lipase cofactors, vitellogenin similarities and functional subdivision of lipoprotein lipase. European Journal of Biochemistry 179, 39–45.CrossRefGoogle ScholarPubMed
Rizek, R. L., Friend, B. & Page, L. (1974). Fat in today's food supply. Level of use and source. Journal of the American Oil Chemists' Society 52, 244–250.CrossRefGoogle Scholar
Roberts, I. M., Montgomery, R. K. & Carey, M. C. (1984). Lingual lipase: Partial purification, hydrolytic properties and comparison with pancreatic lipase. American Journal of Physiology 247G, 385–393.Google Scholar
Ross, C. A. C. & Sammons, H. C. (1955). Non-pancreatic lipase in children with pancreatic fibrosis. Archives of Disease in Childhood 30, 428–431.CrossRefGoogle ScholarPubMed
Roulet, M., Weber, A. M., Paradis, Y., Roy, C. C., Chartraud, L., Lasalle, R. & Morin, C. L. (1980). Gastric emptying and lingual lipase activity in cystic fibrosis. Pediatric Research 14, 1360–1362.CrossRefGoogle ScholarPubMed
Timmermans, M. Y. J., Teuchy, H. & Kupers, L. P. M. (1994). The cDNA sequence encoding bovine pregastric esterase. Gene 147, 259–262.CrossRefGoogle ScholarPubMed
Tiruppathi, C. & Balasubramanian, K. A. (1982). Purification and properties of an acid lipase from human gastric juice. Biochimica et Biophysica Acta 712, 692–697.CrossRefGoogle ScholarPubMed
van Tilbeurgh, H., Egloff, M.-P., Martinez, C., Rugani, N., Verger, R. & Cambillau, C. (1993). Interfacial activation of the lipase-procolipase complex by mixed micelles revealed by X-Ray crystallography. Nature 362, 814–820.CrossRefGoogle ScholarPubMed
van Tilbeurgh, H., Roussel, A., Lalouel, J. M. & Cambillau, C. (1994). Lipoprotein lipase. Molecular model based on the pancreatic lipase X-Ray structure: consequences for heparin binding and catalysis. Journal of Biological Chemistry 269, 4626–4633.CrossRefGoogle ScholarPubMed
van Tilbeurgh, H., Sarda, L., Verger, R. & Cambillau, C. (1992). Structure of the pancreatic lipaseprocolipase complex. Nature 359, 159–162.CrossRefGoogle ScholarPubMed
Volhard, F. (1901). Uber das Fettspaltende fermentdes magens. (On the fat-splitting enzymes of the stomach.). Zeitschrift für Klinische Medizin 42, 414–429.Google Scholar
Winkler, F. K., d'Arey, A. & Hunziker, W. (1990). Structure of human pancreatic lipase. Nature 343, 771–774.CrossRefGoogle ScholarPubMed