Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-26T08:54:12.937Z Has data issue: false hasContentIssue false

Vitamin E and selenium: contrasting and interacting nutritional determinants of host resistance to parasitic and viral infections

Published online by Cambridge University Press:  28 February 2007

Orville A. Levander
Affiliation:
Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, US Department of Agriculture-Agricultural Research Service, Beltsville, Maryland 20705-2350, USA
Arba L. Ager Jr
Affiliation:
Center for Tropical Parasitic Diseases, Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, Florida 33177, USA
Melinda A. Beck
Affiliation:
Frank Porter Graham Child Development Center, University of North Carolina, Chapel Hill, North Carolina 27599-8180, USA
Rights & Permissions [Opens in a new window]

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Symposium on ‘Micronutrient interactions’
Copyright
Copyright © The Nutrition Society 1995

References

Abu-Zeid, Y. A., Hansen, H. S., Jakobsen, P. H., Bygbjerg, I. C. & Dyerberg, J. (1993). No effect of human serum and erythrocytes enriched in n-3 fatty acids by oral intake on Plasmodium falciparum bloodstage parasites in vitro. European Journal of Clinical Nutrition 47, 431436.Google Scholar
Ager, A. L., Fontela, R., Morris, V. C. & Levander, O. A. (1993). A menhaden oil vitamin E-deficient (MO-VE) diet protects against cerebral malaria in a mouse model. FASEB Journal 7, A151.Google Scholar
Ager, A. L., Levander, O.A., Fontela, R., May, R. G. & Morris, V. C. (1991). Chloroquine-resistant (CR) but not-sensitive (CS) Plasmodium vinckei cured in mice by menhaden oil (MO) diet deficient in vitamin E (VE). FASEB Journal 5, A1081.Google Scholar
Ager, A. L., Levander, O. A., Morris, V. C., Fontela, R. & May, R. G. (1992). Once cured of malaria by a menhaden oil-vitamin E-deficient diet, mice become resistant to rechallenge with the parasite regardless of diet fed. FASEB Journal 6, A1212.Google Scholar
Allen, P. C., Danforth, H. D. & Levander, O. A. (1994). High dietary levels of flaxseed oil and fish oil lower cecal lesion scores in broiler chickens infected with the cecal parasite, Eimeria tenella. Proceedings of the 55th Flax Institute of the United States 55, 123126.Google Scholar
Arthur, J. R., Nicol, F. & Beckett, G. J. (1990). Hepatic iodothyronine 5′-deiodinase. The role of selenium. Biochemical Journal 272, 537540.CrossRefGoogle ScholarPubMed
Beck, M. A., Kolbeck, P. C., Rohr, L. H., Shi, Q., Morris, V. C. & Levander, O. A. (1994 a). Vitamin E deficiency intensifies the myocardial injury of coxsackievirus B3 infection of mice. Journal of Nutrition 124, 345358.CrossRefGoogle ScholarPubMed
Beck, M. A., Kolbeck, P. C., Rohr, L. H., Shi, Q., Morris, V. C. & Levander, O. A. (1994 b). Benign human enterovirus becomes virulent in selenium-deficient mice. Journal of Medical Virology 43, 166170.CrossRefGoogle ScholarPubMed
Beck, M. A., Kolbeck, P. C., Shi, Q., Rohr, L. H., Morris, V. C. & Levander, O. A. (1994 c). Increased virulence of a human enterovirus (coxsackievirus B3) in selenium-deficient mice. Journal of Infectious Diseases 170, 351357.CrossRefGoogle ScholarPubMed
Beck, M. A., Morris, V. C. & Levander, O. A. (1994 d). Mice that normally become resistant to CVB3-induced myocarditis because of aging retain their susceptibility when fed a selenium (Se)-deficient diet. FASEB Journal 8, A541.Google Scholar
Beck, M. A., Shi, Q., Morris, V. C. & Levander, O. A. (1995). Rapid genomic evolution of a non-virulent Coxsackievirus B3 in selenium-deficient mice results in selection of identical virulent isolates. Nature Medicine 1, 433436.CrossRefGoogle ScholarPubMed
Blok, W. L., Vogels, M. T. E., Curfs, J. H. A. J., Eling, W. M. C., Buurman, W. A. & Van Der Meer, J. W. M. (1992). Dietary fish-oil supplementation in experimental gram-negative infection and in cerebral malaria in mice. Journal of Infectious Diseases 165, 898903.CrossRefGoogle ScholarPubMed
Boland, P. B., Lackritz, E. M., Kazembe, P. N., Were, J. B. O., Steketee, R. & Campbell, C. C. (1993). Beyond chloroquine: implications of drug resistance for evaluating malaria therapy efficacy and treatment policy in Africa. Journal of Infectious Diseases 167, 932937.CrossRefGoogle Scholar
Caggana, M., Chan, P. & Ramsingh, A. (1993). Identification of a single amino acid residue in the capsid protein VP1 of coxsackievirus B4 that determines the virulent phenotype. Journal of Virology 67, 47974803.CrossRefGoogle ScholarPubMed
Chapman, N. M., Tu, Z., Tracy, S. & Gauntt, C. J. (1994). An infectious cDNA copy of the genome of a non-cardiovirulent coxsackievirus B3 strain: its complete sequence analysis and comparison to the genome of cardiovirulent coxsackievirus. Archives of Virology 135, 115130.CrossRefGoogle Scholar
Chawira, A. N., Warhurst, D. C. & Peters, W. (1986). Qinghaosu resistance in rodent malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene 80, 477480.CrossRefGoogle ScholarPubMed
Clark, I. A., Cowden, W. B. & Butcher, G. A. (1983). Free oxygen radical generators as antimalarial drugs. Lancet i, 234.Google Scholar
Collins, A., Duthie, S. & Ross, M. (1994). Micronutrients and oxidative stress in the aetiology of cancer. Proceedings of the Nutrition Society 53, 6775.CrossRefGoogle ScholarPubMed
Dam, H. (1962). Interrelations between vitamin E and polyunsaturated fatty acids in animals. In Vitamins and Hormones, vol. 20, pp. 527540 [Harris, R. J. and Wool, I. G. editors]. Orlando: Academic Press.Google Scholar
Das, B. S., Mohanty, S., Mishra, S. K., Patnaik, J. K., Satpathy, S. K., Mohanty, D. & Bose, T. K. (1991). Increased cerebrospinal fluid protein and lipid peroxidation products in patients with cerebral malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene 85, 733734.CrossRefGoogle ScholarPubMed
DeWitt, W. B. (1957). Experimental schistosomiasis mansoni in mice maintained on nutritionally deficient diets. I. Effects of a torula yeast ration deficient in factor 3, vitamin E, and cystine. Journal of Parasitology 43, 119128.CrossRefGoogle Scholar
Docampo, R. & Moreno, S. N. J. (1984). Free radical metabolites in the mode of action of chemotherapeutic agents and phagocytic cells on Trypanosoma cruzi. Reviews of Infectious Diseases 6, 223238.CrossRefGoogle ScholarPubMed
Domingo, E. & Holland, J. J. (1994). Mutation rates and rapid evolution of RNA viruses. In The Evolutionary Biology of Viruses, pp. 161184 [Morse, S. S. editor]. New York: Raven Press.Google Scholar
Droge, W., Eck, H. P. & Mihm, S. (1992). HIV-induced cysteine deficiency and T-cell dysfunction - a rationale for treatment with N-acetylcysteine. Immunology Today 13, 211214.CrossRefGoogle ScholarPubMed
Fevang, P., Bjorkman, A. & Hostmark, A. (1992). Suppression of Plasmodium falciparum in vitro by polyunsaturated fatty acids. XIII International Congress for Tropical Medicine and Malaria, Jomtien, Thailand. p. 268 Abstr.Google Scholar
Freedman, A. M., Mak, I. T., Stafford, R. E., Dickens, B. F., Cassidy, M. M., Muesing, R. A. & Weglicki, W. B. (1992). Erythrocytes from magnesium-deficient hamsters display an enhanced susceptibility to oxidative stress. American Journal of Physiology 262, 13711375.CrossRefGoogle ScholarPubMed
Fusco, A. C., Weaver, S., Salafsky, B. & Shibuya, T. (1992). Influence of a menhaden oil diet on cercarial penetration of Schistosoma mansoni. Journal of Parasitology 78, 738740.CrossRefGoogle ScholarPubMed
Ge, K. Y., Wang, S. Q., Bai, J., Xue, A. N., Dang, X. J., Su, C. Q. & Wu, S. Q. (1987). The protective effect of selenium against viral myocarditis in mice. In Selenium in Biology and Medicine – Part B, pp. 761768 [Combs, G. F., Spallholz, J. E., Levander, O. A. and Oldfield, J. E. editors]. New York: Van Nostrand Reinhold.Google Scholar
Godfrey, D. G. (1957 a). Antiparasitic action of dietary cod liver oil upon Plasmodium berghei and its reversal by vitamin ‘E’. Experimental Parasitology 6, 555565.CrossRefGoogle ScholarPubMed
Godfrey, D. G. (1957 b). The influence of dietary cod liver oil and vitamin E upon Babesia rodhaini in mice. Experimental Parasitology 6, 465485.Google Scholar
Godfrey, D. G. (1958). Influence of dietary cod liver oil upon Trypanosoma congolense, T. cruzi, T. vivax and T. brucei Experimental Parasitology 7, 255268.CrossRefGoogle ScholarPubMed
Greenspan, H. C. & Aruoma, O. I. (1994). Oxidative stress and apoptosis in HIV infection: a role for plant-derived metabolites with synergistic antioxidant activity. Immunology Today 15, 209213.CrossRefGoogle ScholarPubMed
Harris, P. L., Ludwig, M. I. & Schwarz, K. (1958). Ineffectiveness of Factor 3-active selenium compounds in resorption-gestation bioassay for vitamin E. Proceedings of the Society for Experimental Biology and Medicine 97, 686688.CrossRefGoogle Scholar
Hein, T. T. & White, N. J. (1993). Qinghaosu. Lancet 341, 603608.CrossRefGoogle Scholar
Hennet, T., Peterhans, E. & Stocker, R. (1992). Alterations in antioxidant defenses in lung and liver of mice infected with influenza virus. Journal of General Virology 73, 3946.CrossRefGoogle Scholar
Hoekstra, W. G. (1975). Biochemical function of selenium and its relation to vitamin E. Federation Proceedings 34, 20832089.Google ScholarPubMed
Jung, A., Fritsch, B., Dieckmann, A., Bleiholder, B. & Otchwemah, R. (1989). Selenium-independent glutathione peroxidase in malaria parasites. In Selenium in Biology and Medicine, pp. 3842 [Wendel, A. editor]. Berlin: Springer Verlag.CrossRefGoogle Scholar
Kahn, R. I. & Prager, D. J. (1994). Interdisciplinary collaborations are a scientific and social imperative. The Scientist 8, 12.Google Scholar
Kelley, D. S. & Daudu, P. A. (1993). Fat intake and immune response. Progress in Food and Nutrition Science 17, 4163.Google ScholarPubMed
Keshan Disease Research Group (1979 a). Epidemiologic studies on the etiologic relationship of selenium and Keshan disease. Chinese Medical Journal 92, 477482.Google Scholar
Keshan Disease Research Group (1979 b). Observations on effect of sodium selenite in prevention of Keshan disease. Chinese Medical Journal 92, 471476.Google Scholar
Klayman, D. L. (1985). Qinghaosu (artemisinin): an antimalarial drug from China. Science 228, 10491055.CrossRefGoogle ScholarPubMed
Kolberg, R. (1994). Finding ‘sustainable’ ways to prevent parasitic diseases. Science 264, 18571859.CrossRefGoogle ScholarPubMed
Kumaratilake, L. M., Robinson, B. S., Ferrante, A. & Poulos, A. (1992). Antimalarial properties of n-3 and n-6 polyunsaturated fatty acids: in vitro effects on Plasmodium falciparium and in vivo effect on P. berghei. Journal of Clinical Investigation 89, 961967.CrossRefGoogle Scholar
Levander, O. A. & Ager, A. L. (1993). Malarial parasites and antioxidant nutrients. Parasitology 107, S95S106.CrossRefGoogle ScholarPubMed
Levander, O. A., Ager, A. L., Morris, V. C. & May, R. G. (1989 a). Qinghaosu, dietary vitamin E, selenium, and cod liver oil: effect on the susceptibility of mice to the malarial parasite Plasmodium yoelii. American Journal of Clinical Nutrition 50, 346352.CrossRefGoogle Scholar
Levander, O. A., Ager, A. L., Morris, V. C. & May, R. G. (1989 b). Menhaden-fish oil in a vitamin E-deficient diet: protection against chloroquine-resistant malaria in mice. American Journal of Clinical Nutrition 50, 12371239.CrossRefGoogle Scholar
Levander, O. A., Ager, A. L., Morris, V. C. & May, R. G. (1989 c). Protective effect of dietary fish oil against malaria in vitamin E-deficient mice. In Health Effects of Fish and Fish Oils, pp. 461467 [Chandra, R. K. editor]. St John's, Canada: ARTS Biomedical Publishers.Google Scholar
Levander, O. A., Ager, A. L., Morris, V. C. & May, R. G. (1990). Plasmodium yoelii: comparative antimalarial activities of dietary fish oils and fish oil concentrates in vitamin E-deficient mice. Experimental Parasitology 70, 323329.CrossRefGoogle ScholarPubMed
Levander, O. A., Ager, A. L., Morris, V. C. & May, R. G. (1991). Protective effect of ground flaxseed or ethyl linolenate in a vitamin E-deficient diet against murine malaria. Nutrition Research 11, 941948.CrossRefGoogle Scholar
Levander, O. A., Fontela, R., Morns, V. C. & Ager, A. L. (1995). Protection against murine cerebral malaria by dietary-induced oxidative stress. Journal of Parasitology 81, 99103.CrossRefGoogle ScholarPubMed
Levander, O. A., Fu, S., Cai, X., Ren, L. & Morris, V. (1994). Effect of menhaden oil ethyl esters (MOEE) on the recrudescence of malaria in patients previously treated with qinghaosu (QHS). FASEB Journal 8, A438.Google Scholar
Maurois, P., Delcourt, Ph., Gueux, E. & Rayssiguier, Y. (1994). Magnesium deficiency protects against Babesia hylomysci and mice become resistant to rechallenge with the parasite regardless of diet fed. Parasitology 108, 245248.CrossRefGoogle ScholarPubMed
Miller, L. H., Good, M. F. & Milon, G. (1994). Malaria pathogenesis. Science 264, 18781883.CrossRefGoogle ScholarPubMed
Morris, V. C., Ager, A. L., May, R. G. & Levander, O. A. (1990). Effect of selenium (Se) and synthetic antioxidants on the antimalarial action of menhaden oil (MO) fed to vitamin E-deficient (—VE) mice. FASEB Journal 4, A504.Google Scholar
Morris, V. C., Hara, I., Levander, O. A., Fusco, A. C. & Salafsky, B. (1994). Effect of dietary menhaden oil (MO) and vitamin E (VE) on Schistosoma mansoni (SM) infection in mice. FASEB Journal 8, A438.Google Scholar
Morse, S. S. (1993 a). Examining the origins of emerging viruses. In Emerging Viruses, pp. 1028 [Morse, S. S. editor]. New York: Oxford University Press.CrossRefGoogle Scholar
Morse, S. S. (1993 b). Emerging Viruses. New York: Oxford University Press.CrossRefGoogle Scholar
National Research Council (1983). Selenium in Nutrition, revised ed. Washington, DC: National Academy Press.Google Scholar
Packer, L. (1991). Protective role of vitamin E in biological systems. American Journal of Clinical Nutrition 53, 1050S1055S.CrossRefGoogle ScholarPubMed
Posner, G. H., Oh, C. H., Webster, H. K., Ager, A. L. & Rossan, R. N. (1994). New, antimalarial, tricyclic, 1,2,4-trioxanes: evaluation in mice and monkeys. American Journal of Tropical Medicine and Hygiene 50, 522526.CrossRefGoogle Scholar
Riemersma, R. A. (1994). Epidemiology and the role of antioxidants in preventing coronary heart disease: a brief review. Proceedings of the Nutrition Society 53, 5965.CrossRefGoogle Scholar
Roche, C., Williams, D. L., Khalife, J., LaPresle, T., Capron, A. & Pierce, R. J. (1994). Cloning and characterization of the gene encoding Schistosoma mansoni glutathione peroxidase. Gene 138, 149152.CrossRefGoogle ScholarPubMed
Scheibel, L. W., Ashton, S. H. & Trager, W. (1979). Plasmodium falciparum: microaerophilic requirements in human blood cells. Experimental Parasitology 47, 410418.CrossRefGoogle Scholar
Schwarz, K. & Foltz, C. M. (1957). Selenium as an integral part of Factor 3 against dietary necrotic liver degeneration. Journal of the American Chemical Society 79, 32923293.CrossRefGoogle Scholar
Simopoulos, A. P. (1991). Omega-3 fatty acids in health and disease and in growth and development. American Journal of Clinical Nutrition 54, 438463.CrossRefGoogle ScholarPubMed
Thompson, J. N. & Scott, M. L. (1969). Role of selenium in the nutrition of the chick. Journal of Nutrition 97, 335342.CrossRefGoogle ScholarPubMed
Thumwood, L. M., Hunt, N. H., Cowden, W. B. & Clark, I. A. (1989). Antioxidants can prevent cerebral malaria in Plasmodium berghei-infected mice. British Journal of Experimental Pathology 70, 293303.Google ScholarPubMed
Williams, D. L., Beck, M. A., Morris, V. C. & Levander, O. A. (1994). Mice genetically resistant to coxsackievirus-induced mycocarditis become susceptible when fed a diet deficient in both selenium (Se) and vitamin E (VE). FASEB Journal 8, A435.Google Scholar
Xia, Y., Hill, K. E. & Burk, R. F. (1989). Biochemical studies of a selenium-deficient population in China: measurement of selenium, glutathione peroxidase and other oxidant defense indices in blood. Journal of Nutrition 119, 13181326.CrossRefGoogle Scholar
Yang, G. Q., Chen, J., Wen, Z., Ge, K., Zhu, L., Chen, X. & Chen, X. (1984). The role of selenium in Keshan disease. Advances in Nutritional Research 6, 203231.CrossRefGoogle ScholarPubMed
Yang, G. Q., Ge, K., Chen, J. & Chen, X. (1988). Selenium-related endemic diseases and the daily selenium requirement of humans. World Review of Nutrition and Dietetics 55, 98152.CrossRefGoogle ScholarPubMed
Yang, F. Y., Lin, Z. H., Xing, J. R., Li, S. G., Yang, J., San, S. & Wu, L. Y. (1994). Se deficiency is a necessary but not sufficient factor required for the pathogenesis of Keshan disease. Journal of Clinical and Biochemical Nutrition 16, 101110.CrossRefGoogle Scholar