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Patent ductus arteriosus closure in small infants weighing less than 1500 g using KA micro plug: steps and tips

Published online by Cambridge University Press:  04 October 2024

Bassel Mohammad Nijres Open the ORCID record for Bassel Mohammad Nijres [Opens in a new window] ,
Moeez Hassan ,
Jimmy Windsor ,
Adrianne Rahde Bischoff Open the ORCID record for Adrianne Rahde Bischoff [Opens in a new window] ,
Patrick J. McNamara  and
Osamah Aldoss
Bassel Mohammad Nijres*
Affiliation:
Pediatric Cardiology Section, Department of Pediatrics, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia
Moeez Hassan
Affiliation:
Division of Pediatric Cardiology, Stead Family Children’s Hospital, University of Iowa, Iowa City, IA, USA
Jimmy Windsor
Affiliation:
Division of Pediatric Anesthesia, Stead Family Children’s Hospital, University of Iowa, Iowa City, IA, USA
Adrianne Rahde Bischoff
Affiliation:
Division of Neonatology, Stead Family Children’s Hospital, University of Iowa, Iowa City, IA, USA
Patrick J. McNamara
Affiliation:
Division of Neonatology, Stead Family Children’s Hospital, University of Iowa, Iowa City, IA, USA
Osamah Aldoss
Affiliation:
Division of Pediatric Cardiology, Stead Family Children’s Hospital, University of Iowa, Iowa City, IA, USA
*
Corresponding author: Bassel Mohammad Nijres; Email: bnijres@kfshrc.edu.sa
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Abstract

Background:

Transcatheter patent ductus arteriosus closure in premature infants is gaining attention with rapidly growing experience. The KA micro plug device poses many favourable features for ductus arteriosus closure in premature infants. The study aimed to describe the technique and outcomes of a KA micro plug in closing the ductus arteriosus in premature infants weighing less than 1500 g.

Methods:

This is a single-centre retrospective study in premature infants with patent ductus arteriosus weighing less than 1500 g who underwent off-label use of a KA micro plug at the Stead Family Children’s Hospital from February 2022 to December 2023.

Results:

Eighteen premature infants weighing less than 1500 g underwent attempted transcatheter ductus arteriosus closure using a KA micro plug device. Median weight, age, and corrected gestational age at the procedure were 943 g (682–1225), 26 days (9–79), and 28.5 weeks (25.6–32), respectively. The procedure was successful with complete closure achieved in all patients. No major haemodynamic instabilities were encountered. No catheterization-related complications were encountered. On a median follow-up of 10.9 months (0.1–19), all patients are alive with the device in a good position without residual shunt or abnormal findings.

Conclusion:

KA micro plug device for patent ductus arteriosus in infants weighing less than 1500 g is feasible, safe, and effective. We recommend that manufacturers of devices used to close the ductus arteriosus in small infants enhance both the devices and their delivery systems to simplify the procedure and mitigate the risk of haemodynamic instability.

Keywords

patent ductus arteriosus closurepremature infantKA micro plug
Type
Original Article
Information
Cardiology in the Young , Volume 34 , Issue 8 , August 2024 , pp. 1809 - 1814
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Copyright
© The Author(s), 2024. Published by Cambridge University Press

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