On July 1,1980, at four major medical institutions across the United States, the National Cancer Institute began testing Laetrile on cancer patients on whom all other therapy has failed. The study calls for 200 patients to receive the drug, along with a natural food diet. Results should be known in two years, and should demonstrate once and for all whether or not Laetrile has any cancer inhibiting effects. The study was undertaken primarily because of the large amount of publicity proponents of Laetrile have generated over the past five years, rather than any independent evidence that Laetrile may be an effective anticancer agent. Its commencement, however, provides a useful opportunity to review the legal status of Laetrile, and to suggest a possible approach to the controversy it has caused.