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Mental disorders and the risk of adult violent and psychological victimisation: a prospective, population-based study

Published online by Cambridge University Press:  17 January 2019

C. Christ*
Affiliation:
Department of Psychiatry, Amsterdam UMC/GGZ inGeest, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands Department of Research, Arkin Mental Health Care, Amsterdam, The Netherlands Amsterdam Public Health Research Institute, Amsterdam UMC, The Netherlands
M. Ten Have
Affiliation:
Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands
R. de Graaf
Affiliation:
Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands
D. J. F. van Schaik
Affiliation:
Department of Psychiatry, Amsterdam UMC/GGZ inGeest, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands Amsterdam Public Health Research Institute, Amsterdam UMC, The Netherlands
M. J. Kikkert
Affiliation:
Department of Research, Arkin Mental Health Care, Amsterdam, The Netherlands
J. J. M. Dekker
Affiliation:
Department of Research, Arkin Mental Health Care, Amsterdam, The Netherlands Department of Clinical Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
A. T. F. Beekman
Affiliation:
Department of Psychiatry, Amsterdam UMC/GGZ inGeest, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands Amsterdam Public Health Research Institute, Amsterdam UMC, The Netherlands
*
Author for correspondence: C. Christ, E-mail: c.christ@ggzingeest.nl
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Abstract

Aims

Psychiatric patients are at increased risk to become victim of violence. It remains unknown whether subjects of the general population with mental disorders are at risk of victimisation as well. In addition, it remains unclear whether the risk of victimisation differs across specific disorders. This study aimed to determine whether a broad range of mood, anxiety and substance use disorders at baseline predict adult violent (physical and/or sexual) and psychological victimisation at 3-year follow-up, also after adjustment for childhood trauma. Furthermore, this study aimed to examine whether specific types of childhood trauma predict violent and psychological victimisation at follow-up, after adjustment for mental disorder. Finally, this study aimed to examine whether the co-occurrence of childhood trauma and any baseline mental disorder leads to an incrementally increased risk of future victimisation.

Methods

Data were derived from the first two waves of the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2): a psychiatric epidemiological cohort study among a nationally representative adult population. Mental disorders were assessed using the Composite International Diagnostic Interview version 3.0. Longitudinal associations between 12 mental disorders at baseline and violent and psychological victimisation at 3-year follow-up (n = 5303) were studied using logistic regression analyses, with adjustment for sociodemographic characteristics and childhood trauma. Furthermore, the moderating effect of childhood trauma on these associations was examined.

Results

Associations with victimisation varied considerably across specific mental disorders. Only alcohol dependence predicted both violent and psychological victimisation after adjustment for sociodemographic characteristics and childhood trauma. Depression, panic disorder, social phobia, generalised anxiety disorder and alcohol dependence predicted subsequent psychological victimisation in the fully adjusted models. All types of childhood trauma independently predicted violent and psychological victimisation after adjustment for any mental disorder. The presence of any childhood trauma moderated the association between any anxiety disorder and psychological victimisation, whereas no interaction between mental disorder and childhood trauma on violent victimisation existed.

Conclusions

The current study shows that members of the general population with mental disorders are at increased risk of future victimisation. However, the associations with violent and psychological victimisation vary considerably across specific disorders. Clinicians should be aware of the increased risk of violent and psychological victimisation in individuals with these mental disorders – especially those with alcohol dependence – and individuals with a history of childhood trauma. Violence prevention programmes should be developed for people at risk. These programmes should not only address violent victimisation, but also psychological victimisation.

Type
Original Articles
Creative Commons
Creative Common License - CCCreative Common License - BYCreative Common License - NCCreative Common License - SA
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike licence (http://creativecommons.org/licenses/by-nc-sa/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the same Creative Commons licence is included and the original work is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use.
Copyright
Copyright © The Author(s) 2019

Introduction

Mental disorders have repeatedly been related to violence perpetration (Pulay et al., Reference Pulay, Dawson, Hasin, Goldstein, Ruan, Pickering, Huang, Chou and Grant2008; Fazel et al., Reference Fazel, Lichtenstein, Grann, Goodwin and Långström2010, Reference Fazel, Wolf, Chang, Larsson, Goodwin and Lichtenstein2015). Correspondingly, stigmatising stereotypes regarding the dangerousness of psychiatric patients have become common (Torrey, Reference Torrey2011; Jorm et al., Reference Jorm, Reavley and Ross2012). However, research has revealed psychiatric patients to be victim of violence more often than perpetrator (Choe et al., Reference Choe, Teplin and Abram2008; Maniglio, Reference Maniglio2009). Moreover, psychiatric patients are violently victimised more often than other members of the general population (Teplin et al., Reference Teplin, Mcclelland, Abram and Weiner2005; Kamperman et al., Reference Kamperman, Henrichs, Bogaerts, Lesaffre, Wierdsma, Ghauharali, Swildens, Nijssen, Van Der Gaag, Theunissen, Delespaul, Van, Van Busschbach, Kroon, Teplin, Van De Mheen and Mulder2014; Khalifeh et al., Reference Khalifeh, Oram, Osborn, Howard and Johnson2016). Victimisation negatively impacts mental health (Resnick et al., Reference Resnick, Acierno and Kilpatrick1997; Dworkin et al., Reference Dworkin, Menon, Bystrynski and Allen2017), and increases service use (Robinson and Keithley, Reference Robinson and Keithley2000). In psychiatric patients, victimisation is associated with more severe symptomatology, substance abuse (Goodman et al., Reference Goodman, Salyers, Mueser, Rosenberg, Swartz, Essock, Osher, Butterfield and Swanson2001; Walsh et al., Reference Walsh, Moran, Scott, Mckenzie, Burns, Creed, Tyrer, Murray and Fahy2003) and lower quality of life (Lam and Rosenheck, Reference Lam and Rosenheck1998). Furthermore, victimisation increases the risk of revictimisation (Roodman and Clum, Reference Roodman and Clum2001; Dean et al., Reference Dean, Moran, Fahy, Tyrer, Leese, Creed, Burns, Murray and Walsh2007).

To date, research is mostly limited to clinical samples, such as patients with psychotic disorders (e.g. Dean et al., Reference Dean, Moran, Fahy, Tyrer, Leese, Creed, Burns, Murray and Walsh2007) or substance use disorders (SUD; Stevens et al., Reference Stevens, Berto, Frick, Kerschl, Mcsweeny, Schaaf, Tartari, Turnbull, Trinkl, Uchtenhagen, Waidner and Werdenich2007). It remains unclear whether subjects of the general population with mood, anxiety and substance use disorders are at increased risk of victimisation as well. Moreover, it remains unclear whether the risk of victimisation differs across specific disorders. The few studies that have addressed victimisation in the general population have demonstrated an increased risk for people with any mental disorder (Hart et al., Reference Hart, De Vet, Moran, Hatch and Dean2012), anxiety disorder, alcohol dependence (Silver et al., Reference Silver, Arseneault, Langley, Caspi and Moffitt2005) and depression (Acierno et al., Reference Acierno, Resnick, Kilpatrick, Saunders and Best1999; Krahé and Berger, Reference Krahé and Berger2017) – although results have been somewhat inconsistent (Acierno et al., Reference Acierno, Resnick, Kilpatrick, Saunders and Best1999; Silver et al., Reference Silver, Arseneault, Langley, Caspi and Moffitt2005).

Despite their value, these previous studies have important limitations. First, all have limited generalisability, since they exclusively addressed women (Acierno et al., Reference Acierno, Resnick, Kilpatrick, Saunders and Best1999), students (Krahé and Berger, Reference Krahé and Berger2017) or narrow birth cohorts (Silver et al., Reference Silver, Arseneault, Langley, Caspi and Moffitt2005; Hart et al., Reference Hart, De Vet, Moran, Hatch and Dean2012). Second, all failed to address a broad range of specific mental disorders. Third, all focused on violent victimisation and did not include psychological victimisation, which is associated with even worse mental health than violent victimisation (Friborg et al., Reference Friborg, Emaus, Rosenvinge, Bilden, Olsen and Pettersen2015; Nelson et al., Reference Nelson, Klumparendt, Doebler and Ehring2017). Finally, although most controlled for relevant confounders, such as sociodemographic characteristics, lifetime victimisation (Acierno et al., Reference Acierno, Resnick, Kilpatrick, Saunders and Best1999) and participants’ own violent behaviour (Silver et al., Reference Silver, Arseneault, Langley, Caspi and Moffitt2005), they did not take childhood trauma into account.

A history of childhood trauma is an important risk factor for adult victimisation in the general population (Roodman and Clum, Reference Roodman and Clum2001), next to sociodemographic characteristics such as younger age, low socioeconomic status (Acierno et al., Reference Acierno, Resnick, Kilpatrick, Saunders and Best1999; Wittebrood, Reference Wittebrood2006) and being single (Silver et al., Reference Silver, Arseneault, Langley, Caspi and Moffitt2005). Since childhood trauma has consistently been identified as a risk indicator for both mental disorders (Kessler et al., Reference Kessler, Davis and Kendler1997; Hovens et al., Reference Hovens, Wiersma, Giltay, Van Oppen, Spinhoven, Penninx and Zitman2010) and adult victimisation (Roodman and Clum, Reference Roodman and Clum2001; Barrios et al., Reference Barrios, Gelaye, Zhong, Nicolaidis, Rondon, Garcia, Sanchez, Sanchez and Williams2015), childhood trauma may act as a confounder in the association between mental disorder and subsequent victimisation. In a large population-based twin cohort, childhood sexual abuse increased the risk of adult sexual victimisation after adjustment for lifetime psychopathology, indicating an independent effect of childhood sexual abuse on adult sexual victimisation. Vice versa, lifetime psychopathology was associated with adult sexual victimisation after adjustment for childhood sexual abuse (Werner et al., Reference Werner, Mccutcheon, Challa, Agrawal, Lynskey, Conroy, Statham, Madden, Henders and Todorov2016). Since this study had a cross-sectional design and only addressed adult sexual victimisation, it remains unknown whether mental disorders and childhood trauma each have an independent effect on future violent and psychological victimisation. Furthermore, it remains unknown whether their co-occurrence leads to an incrementally increased risk of adult victimisation.

This prospective study aims to determine whether a range of mood, anxiety and substance use disorders at baseline predict adult violent and psychological victimisation at 3-year follow-up, also after adjustment for childhood trauma. This study is the first to examine these longitudinal associations in a large, representative community sample, differentiating between a wide range of mental disorders and including both violent and psychological victimisation. We hypothesised that (a) the presence of any mood, anxiety and substance use disorders predicts adult violent and psychological victimisation after adjustment for sociodemographic characteristics and childhood trauma; (b) a history of childhood trauma predicts adult violent and psychological victimisation after adjustment for any mental disorder and (c) the co-occurrence of any mental disorder and childhood trauma leads to an incrementally increased risk of adult victimisation.

Method

Sample

This study utilised data from the first two waves of the second Netherlands Mental Health Survey and Incidence Study (NEMESIS-2): an epidemiological cohort study on the prevalence, incidence and course of mental disorders in the Dutch general population aged 18–64 years (de Graaf et al., Reference De Graaf, Ten Have and Van Dorsselaer2010). Participants were selected based on a multistage, stratified random household sample. Based on the most recent birthday at first contact, one individual aged 18–64 years with sufficient fluency in the Dutch language was randomly selected from each household. Institutional addresses – and accordingly, institutionalised individuals (i.e. those living in hospices, prisons) – were excluded. Those temporarily living in institutions could be interviewed after they had returned home.

In the first wave (T 0), 6646 persons were interviewed (response rate 65.1%). This sample was nationally representative, although younger subjects were somewhat underrepresented (de Graaf et al., Reference De Graaf, Ten Have and Van Dorsselaer2010). Three years after T 0, all respondents were approached for follow-up, of whom 5303 persons were interviewed again (response rate 80.4%, with those deceased excluded). A previous study demonstrated that attrition at follow-up was not significantly linked to any mental disorder, any mood, anxiety or substance use disorder, or any individual mental disorder at baseline, after controlling for sociodemographic characteristics (de Graaf et al., Reference De Graaf, Van Dorsselaer, Tuithof and Ten Have2013).

Procedures

The first wave took place from November 2007 to July 2009 and the second wave from November 2010 to June 2012, with a mean period of 3 years and 7 days between both interviews. The interviews were laptop computer-assisted, and nearly all were conducted at the respondent's home. The average interview duration was 95 min for T 0, and 84 min for T 1. The study was approved by a medical ethics committee and has been carried out in accordance with the 1964 Declaration of Helsinki and its later amendments. All respondents provided written informed consent. A more comprehensive description of the design is provided elsewhere (de Graaf et al., Reference De Graaf, Ten Have and Van Dorsselaer2010).

Measures

Victimisation

At T 1, participants were asked whether they had experienced physical, sexual or psychological victimisation since T 0. Physical victimisation included kicking, biting, hitting with a hand or an object, or trying to wound with an object (i.e. gun, knife, piece of wood, scissors or other) or hot water. Sexual victimisation included unwanted sexual touching, forced undressing and forced sexual activity. Psychological victimisation included name-calling, offending, belittling, punishing unjustly, blackmailing or threatening, which largely corresponds to the definitions used in previous research (Fink et al., Reference Fink, Bernstein, Handelsman, Foote and Lovejoy1995; Straus et al., Reference Straus, Hamby, Boney-Mccoy and Sugarman1996).

To increase the likelihood of victimisation being reported, types of victimisation were not described as such, but were listed in a booklet and referred to by number. Participants were asked if and how often they had experienced each type of victimisation since T 0. Psychological victimisation was defined as present if it had occurred more than once, which is consistent with previous research (Glaser, Reference Glaser2002; McLaughlin et al., Reference McLaughlin, Conron, Koenen and Gilman2010; Honings et al., Reference Honings, Drukker, Ten Have, De Graaf, Van Dorsselaer and Van Os2017). Physical and sexual abuse were defined as present if it had occurred on one or more occasions, which is also consistent with previous research (Kessler et al., Reference Kessler, Molnar, Feurer and Appelbaum2001; Miller et al., Reference Miller, Breslau, Petukhova, Fayyad, Green, Kola, Seedat, Stein, Tsang and Viana2011; Ten Have et al., Reference Ten Have, De Graaf, Van Weeghel and Van Dorsselaer2014). Each type of victimisation was coded dichotomously (absent/present).

Mental disorders

The presence of mental disorders was determined with the Composite International Diagnostic Interview (CIDI) version 3.0 (Haro et al., Reference Haro, Arbabzadeh-Bouchez, Brugha, De Girolamo, Guyer, Jin, Lepine, Mazzi, Reneses and Vilagut2006): a structured lay-administered diagnostic interview that generates DSM-IV diagnoses. This instrument was developed and adapted for use in the World Mental Health Survey Initiative (Kessler and Üstün, Reference Kessler and Üstün2004). The CIDI 3.0 version used in NEMESIS-2 was an improvement of the Dutch version used in this initiative.

This paper encompasses the 12-month prevalence of the following disorders assessed at baseline: mood disorders (major depression, dysthymia and bipolar disorder), anxiety disorders (panic disorder, agoraphobia without panic disorder, social phobia, specific phobia and generalised anxiety disorder [GAD]) and SUD (alcohol/drug abuse and dependence). Clinical calibration studies have demonstrated that the CIDI 3.0 assesses mood, anxiety and substance use disorders with generally good validity in comparison with blinded clinical reappraisal interviews (Haro et al., Reference Haro, Arbabzadeh-Bouchez, Brugha, De Girolamo, Guyer, Jin, Lepine, Mazzi, Reneses and Vilagut2006).

Sociodemographic characteristics

At T 0, sex, age, education, living situation, employment status and household income situation were assessed. Age and educational attainment were included in the analyses as categorical variables with five and four categories, respectively. Employment status (paid job/no paid job), living situation (with partner/without partner) and household income situation (sufficient/insufficient income to make a living) were coded dichotomously.

Childhood trauma

Participants were asked whether and how often they had experienced physical, sexual or psychological abuse, or bullying before the age of 16 years. Childhood physical abuse was defined as kicking, hitting with a hand or an object, biting or trying to wound with an object or hot water. Childhood sexual abuse was defined as unwanted sexual touching, forced undressing and forced sexual activity. Psychological abuse included name-calling, offending, belittling, punishing unjustly, blackmailing, threatening, one's siblings being favoured and consistent lack of parental attention/support. To increase the likelihood of childhood trauma being reported, these experiences were listed in a booklet and referred to by number. Psychological abuse was considered present if it had occurred more than once; physical and sexual abuse were considered present if it had occurred on one or more occasions (consistent with Kessler et al., Reference Kessler, Molnar, Feurer and Appelbaum2001; Glaser, Reference Glaser2002; Miller et al., Reference Miller, Breslau, Petukhova, Fayyad, Green, Kola, Seedat, Stein, Tsang and Viana2011). Bullying was considered present if participants answered affirmative when asked whether they had been bullied regularly before the age of 16. Each type of childhood trauma was coded dichotomously (absent/present).

Statistical analysis

All analyses were performed with STATA version 12.1, using weighted data to correct for differences in response rates in several sociodemographic groups at both waves and differences in the probability of selection of respondents within households at baseline. Robust standard errors were calculated to obtain correct 95% confidence intervals (CIs) and p-values (Skinner et al., Reference Skinner, Holt and Smith1989). Based on the literature, gender (Walsh et al., Reference Walsh, Moran, Scott, Mckenzie, Burns, Creed, Tyrer, Murray and Fahy2003; de Waal et al., Reference De Waal, Christ, Dekker, Kikkert, Lommerse, Van Den Brink and Goudriaan2018), age (Walsh et al., Reference Walsh, Moran, Scott, Mckenzie, Burns, Creed, Tyrer, Murray and Fahy2003), living situation (Miethe and McDowall, Reference Miethe and Mcdowall1993; Xu et al., Reference Xu, Olfson, Villegas, Okuda, Wang, Liu and Blanco2013), household income situation (Honkonen et al., Reference Honkonen, Henriksson, Koivisto, Stengard and Salokangas2004) and childhood trauma (Werner et al., Reference Werner, Mccutcheon, Challa, Agrawal, Lynskey, Conroy, Statham, Madden, Henders and Todorov2016) were selected as potential confounders. All were univariately associated with both mental disorder and adult victimisation and were included as covariates in the models.

First, 3-year prevalence rates of adult physical, sexual and psychological victimisation were calculated. Second, descriptive analyses and logistic regression analyses adjusted for gender and age were used to examine sociodemographic characteristics as correlates of victimisation at follow-up (Table 1). Third, logistic regression analyses were performed to examine associations between 12-month mental disorders at baseline and adult violent and psychological victimisation at follow-up (Table 2), adjusted for sociodemographic characteristics (Model 1) and any childhood trauma (Model 2). In these regression analyses, physical and sexual victimisations were combined into the category ‘violent victimisation’ to increase power. Fourth, associations between all types of childhood trauma at baseline and violent and psychological victimisation at follow-up were examined using logistic regression analyses (Table 3), adjusted for sociodemographic characteristics (Model 1) and additionally for any mental disorder at baseline (Model 2).

Table 1. Sociodemographic characteristics at baseline as correlates of adult victimisation at follow-up in the general population (n  =  5303), in unweighted numbers (n), weighted column percentages (%) and weighted adjusted odds ratios (ORs) with 95% confidence intervals (CIs)

Significant results are shown in bold.

*p < 0.05 **p < 0.01 and ***p < 0.001.

a ORs are adjusted for gender and age.

Table 2. Associations between 12-month mental disorders at baseline and adult victimisation at 3-year follow-up (n  =  5171) in unweighted numbers (n) and weighted adjusted odds ratios (ORs) with 95% confidence intervals (CIs)

Significant results are shown in bold.

*p < 0.05 **p < 0.01 and ***p < 0.001.

Model 1 is adjusted for gender, age, partner status and household income situation.

Model 2 is adjusted for gender, age, partner status, household income situation and any childhood trauma.

Table 3. Associations between childhood trauma subtypes at baseline and adult victimisation at 3-year follow-up in the general population (n  =  5171), in unweighted numbers (n) and weighted adjusted odds ratios (ORs) with 95% confidence intervals (CIs)

Significant results are shown in bold.

*p < 0.05 **p < 0.01 and ***p < 0.001.

Model 1 is adjusted for gender, age, partner status and household income situation.

Model 2 is adjusted for gender, age, partner status, household income situation and any mental disorder.

Finally, to analyse whether any childhood trauma modified the effect of mental disorder on adult victimisation, we used an additive model, rather than a multiplicative model (guided by previous work; e.g. Ten Have et al., Reference Ten Have, Vollebergh, Bijl and Ormel2002; Tuithof et al., Reference Tuithof, Ten Have, Van Den Brink, Vollebergh and De Graaf2012). Additive interaction existed if the combined effect of mental disorder and any childhood trauma on adult victimisation was stronger than the sum of separate effects. The presence of additive interaction effects was determined by comparing this observed combined effect with the expected odds ratio (OR) in case of no interaction (i.e. the sum of the separate effects of childhood trauma and mental disorder). If the expected OR in case of no interaction lies below the lower limit of the CI of the combined effect, additive interaction is assumed (Hosmer and Lemeshow, Reference Hosmer and Lemeshow1992; Ahlbom and Alfredsson, Reference Ahlbom and Alfredsson2005; Rothman, Reference Rothman2012). We tested eight interaction effects: any childhood trauma by any mood disorder, any anxiety disorder, any SUD and any mental disorder, for both violent and psychological victimisation. Listwise deletion was used for missing data. Two-tailed testing procedures were used with 0.05 alpha levels in all analyses.

Results

Sociodemographic characteristics as correlates of victimisation

Of all 5303 participants who completed the T 1 follow-up measure, 237 (5.5%) reported having experienced physical victimisation, 34 (0.7%) reported sexual victimisation and 963 (19.7%) reported psychological victimisation since T 0. Respondents with younger age and respondents with insufficient income to make a living were more likely to have experienced each type of victimisation, whereas respondents without a partner were more likely to have experienced sexual and psychological victimisation. Gender, education level and employment status were not associated with victimisation (Table 1).

Associations between mental disorders and victimisation

Violent victimisation

Respondents with any mood disorder in the 12 months preceding T 0 were significantly more likely to have experienced violent victimisation in the following 3 years, after adjustment for sociodemographic characteristics (Table 2; Model 1). This did not apply for respondents with any anxiety disorder or any SUD. Of the individual disorders, only bipolar disorder and alcohol dependence were associated with violent victimisation. After additional adjustment for any childhood trauma (Model 2), of all main categories and individual disorders, only alcohol dependence remained significantly associated with violent victimisation – increasing the odds more than 13-fold.

Psychological victimisation

Regarding psychological victimisation, a different picture emerged: both any mood disorder and any anxiety disorder were significantly associated with psychological victimisation in Model 1, whereas any SUD was not. In contrast to the limited correlates of violent victimisation, a large number of individual disorders predicted psychological victimisation after adjustment for sociodemographic characteristics: major depression, panic disorder, social phobia, specific phobia, GAD and alcohol dependence. Except for specific phobia, all abovementioned correlates remained significant after additional adjustment for childhood trauma. The strongest associations were found for alcohol dependence and GAD, which increased the odds almost 5-fold and more than 2-fold, respectively.

Associations between childhood trauma and victimisation

Respondents with a history of any childhood trauma were more likely to experience any adult victimisation after adjustment for sociodemographic characteristics (OR  =  2.46 [1.62–3.73], p < 0.001). More specifically, respondents with a history of each type of childhood trauma – physical, sexual or psychological abuse, or having been bullied – were more likely to experience adult violent and psychological victimisation, as shown in Table 3 (Model 1). All associations remained significant after additional adjustment for any mental disorder (Model 2), indicating an independent effect on adult violent and psychological victimisation for each type of childhood trauma. The strongest associations were found between childhood sexual abuse and violent victimisation and between childhood psychological abuse and psychological victimisation, although all yielded similar magnitudes.

We found an additive interaction effect of any childhood trauma and any anxiety disorder on psychological victimisation (i.e. the expected effect lay below the lower limit of the CI for the observed combined effect: 2.22 v. 3.32, 95% CI 2.41–4.56). Hence, the co-occurrence of any childhood trauma and any anxiety disorder incrementally increased the risk of psychological victimisation. Additional logistic regression analyses, performed separately for individuals with and without a history of childhood trauma, showed that presence of any anxiety disorder was associated with an increased risk of adult psychological victimisation in individuals with a history of childhood trauma (OR = 1.48 [1.08–2.03], p  =  0.014). In people without a history of childhood trauma, however, no significant association between any anxiety disorder and psychological victimisation existed. We found no other interaction effects on psychological victimisation, nor did we find any interaction effects for childhood trauma and mental disorder on violent victimisation. More details on these results are provided in online Supplementary material.

Discussion

This study is the first to determine longitudinal associations between a broad range of mental disorders and adult violent and psychological victimisation in the general population, taking childhood trauma into account. Importantly, this study demonstrates that associations with victimisation vary considerably across specific disorders. Contrary to our expectations, only alcohol dependence yielded a consistent effect on both types of victimisation after accounting for the effect of childhood trauma. Furthermore, this study shows that individuals with depression, panic disorder, social phobia and GAD are at risk of subsequent psychological victimisation, also after accounting for childhood trauma. This study also demonstrates that each type of childhood trauma is not only a risk factor for adult violent victimisation, but also for psychological victimisation, after adjustment for mental disorder. Finally, our results indicate that the co-occurrence of childhood trauma and any anxiety disorder leads to an incrementally increased risk of psychological victimisation.

Main findings

Violent victimisation

Our finding that alcohol dependence is strongly associated with future violent victimisation only partly corresponds to previous research (Silver et al., Reference Silver, Arseneault, Langley, Caspi and Moffitt2005). Remarkably, alcohol abuse was not associated with victimisation, which contrasts numerous studies documenting a positive association between problematic alcohol use and sexual victimisation in female samples (Testa and Livingston, Reference Testa and Livingston2009). However, most were cross-sectional and unable to draw conclusions on causality. Evidence from prospective studies remains mixed: although some confirmed this association (Combs-Lane and Smith, Reference Combs-Lane and Smith2002; Messman-Moore et al., Reference Messman-Moore, Coates, Gaffey and Johnson2008), others could not (Gidycz et al., Reference Gidycz, Hanson and Layman1995; Acierno et al., Reference Acierno, Resnick, Kilpatrick, Saunders and Best1999; Messman-Moore et al., Reference Messman-Moore, Ward and Zerubavel2013).

The increased risk of violent victimisation among people with alcohol dependence might be explained by deficits in executive functions. Difficulties with problem-solving and decision-making under risky conditions have been commonly observed in people with chronic alcoholism (Le Berre et al., Reference Le Berre, Fama and Sullivan2017). Furthermore, alcohol dependence is associated with deficits in social cognition, such as impaired recognition of anger and difficulties reading others’ state of mind (Kornreich et al., Reference Kornreich, Philippot, Foisy, Blairy, Raynaud, Dan, Hess, Noël, Pelc and Verbanck2002; Bora and Zorlu, Reference Bora and Zorlu2017), even after periods of abstinence (Kornreich et al., Reference Kornreich, Philippot, Foisy, Blairy, Raynaud, Dan, Hess, Noël, Pelc and Verbanck2002; Oscar-Berman et al., Reference Oscar-Berman, Valmas, Sawyer, Ruiz, Luhar and Gravitz2014). Presumably, these deficits may hamper one's capacity to cope with conflicts and risky situations. An alternative explanation, however, may be found in the victim-perpetrator overlap: people with alcohol dependence are not only at risk to become victim of violence, but also to commit violence themselves (Pulay et al., Reference Pulay, Dawson, Hasin, Goldstein, Ruan, Pickering, Huang, Chou and Grant2008; Elbogen and Johnson, Reference Elbogen and Johnson2009; Fazel et al., Reference Fazel, Lichtenstein, Grann, Goodwin and Långström2010). It remains unclear whether these factors uniquely apply to people with alcohol dependence, and not to people with alcohol abuse and other mental disorders.

Unexpectedly, most mental disorders were not associated with violent victimisation. These findings are largely in contrast with those observed in clinical (Stevens et al., Reference Stevens, Berto, Frick, Kerschl, Mcsweeny, Schaaf, Tartari, Turnbull, Trinkl, Uchtenhagen, Waidner and Werdenich2007; Meijwaard et al., Reference Meijwaard, Kikkert, De Mooij, Lommerse, Peen, Schoevers, Van, De, Bockting and Dekker2015) and population-based samples (Acierno et al., Reference Acierno, Resnick, Kilpatrick, Saunders and Best1999; Krahé and Berger, Reference Krahé and Berger2017). Although the presence of any mood disorder and bipolar disorder was associated with more violent victimisation, our results indicate that this increased risk should be attributed to childhood trauma rather than to these mental disorders. Previous studies may have overestimated the association between mental disorders and violent victimisation due to methodological shortcomings, such as a cross-sectional design (Stevens et al., Reference Stevens, Berto, Frick, Kerschl, Mcsweeny, Schaaf, Tartari, Turnbull, Trinkl, Uchtenhagen, Waidner and Werdenich2007; Meijwaard et al., Reference Meijwaard, Kikkert, De Mooij, Lommerse, Peen, Schoevers, Van, De, Bockting and Dekker2015), a less representative sample (Acierno et al., Reference Acierno, Resnick, Kilpatrick, Saunders and Best1999; Hart et al., Reference Hart, De Vet, Moran, Hatch and Dean2012; Krahé and Berger, Reference Krahé and Berger2017), or lack of adjustment for childhood trauma or previous victimisation (Stevens et al., Reference Stevens, Berto, Frick, Kerschl, Mcsweeny, Schaaf, Tartari, Turnbull, Trinkl, Uchtenhagen, Waidner and Werdenich2007; Hart et al., Reference Hart, De Vet, Moran, Hatch and Dean2012; Meijwaard et al., Reference Meijwaard, Kikkert, De Mooij, Lommerse, Peen, Schoevers, Van, De, Bockting and Dekker2015; Krahé and Berger, Reference Krahé and Berger2017). However, since the prevalence of violent victimisation was relatively low in our sample (n  =  263, 6%), power to detect associations was somewhat limited.

Psychological victimisation

This is the first study to determine longitudinal associations between mental disorders and adult psychological victimisation. Our results indicate that people with alcohol dependence, depressive disorder, panic disorder, social phobia or GAD are at risk of psychological victimisation after adjustment for childhood trauma. Studies on psychological victimisation are scarce, but our results are largely in line with research in children and adolescents that indicated depressive symptoms and anxious-withdrawn behaviour to be associated with subsequent psychological victimisation (Shapero et al., Reference Shapero, Hamilton, Liu, Abramson and Alloy2013; Brendgen and Poulin, Reference Brendgen and Poulin2018).

One explanation for the increased risk of psychological victimisation in people with depressive and anxiety disorders might be found in their high levels of interpersonal problems, which seem to persist even after remission (scar effect) (Ehring et al., Reference Ehring, Fischer, Schnuelle, Boesterling and Tuschen-Caffier2008; Saris et al., Reference Saris, Aghajani, Van Der Werff, Van Der Wee and Penninx2017). Symptoms of depressive and anxiety disorders, such as irritability, apathy, avoidance and reassurance seeking, may cause frustration in social relationships, which in turn may evoke psychological violence. An alternative explanation may lie in the fact that individuals with a depressive or anxiety disorder show a bias towards negative information (Mathews and MacLeod, Reference Mathews and Macleod2005; Maoz et al., Reference Maoz, Eldar, Stoddard, Pine, Leibenluft and Bar-Haim2016; Carlisi and Robinson, Reference Carlisi and Robinson2018). Their tendency to perceive ambiguous information as negative may cause them to appraise and report ambiguous situations as psychological victimisation more often than others. Since psychological victimisation is generally more ambiguous than violent victimisation, perception bias appears to be mainly applicable to psychological victimisation. Future research should further explore the specific context of psychological victimisation incidents and should clarify why some mental disorders increase one's risk of psychological victimisation, while other disorders do not.

Childhood trauma

Our results fully support previous studies indicating that individuals who have been exposed to any subtype of childhood trauma are at risk of adult violent victimisation (Roodman and Clum, Reference Roodman and Clum2001; Widom et al., Reference Widom, Dumont and Czaja2007; Barrios et al., Reference Barrios, Gelaye, Zhong, Nicolaidis, Rondon, Garcia, Sanchez, Sanchez and Williams2015; Werner et al., Reference Werner, Mccutcheon, Challa, Agrawal, Lynskey, Conroy, Statham, Madden, Henders and Todorov2016), and build upon these by showing this pattern also holds for adult psychological victimisation. Moreover, this study shows that these effects are independent of mental disorder. The mechanisms through which childhood trauma leads to adult revictimisation remain largely unknown (see Messman-Moore and Long, Reference Messman-Moore and Long2003, for a review). Although problematic alcohol use (Gidycz et al., Reference Gidycz, Hanson and Layman1995; Ullman et al., Reference Ullman, Najdowski and Filipas2009; Strøm et al., Reference Strøm, Kristian Hjemdal, Myhre, Wentzel-Larsen and Thoresen2017), interpersonal problems (Strøm et al., Reference Strøm, Kristian Hjemdal, Myhre, Wentzel-Larsen and Thoresen2017) and emotion dysregulation (Messman-Moore et al., Reference Messman-Moore, Ward and Zerubavel2013) have been identified as mediators in this relationship, results remain inconsistent.

Our results indicate that the co-occurrence of childhood trauma and any anxiety disorder leads to an increased risk of psychological victimisation. Compared with individuals with either a history of childhood trauma or any anxiety disorder, individuals with both childhood trauma and any anxiety disorder may show more anxious-withdrawn behaviour, which was associated with subsequent psychological victimisation in adolescents (Brendgen and Poulin, Reference Brendgen and Poulin2018). Contrary to our expectations, we found no evidence that the co-occurrence of childhood trauma and mental disorders leads to an increased risk of violent victimisation. However, since the prevalence of violent victimisation was relatively low (n  =  263, 6%), power to estimate interaction effects was somewhat limited.

Strengths and limitations

Major strengths of this study are its prospective design, the large, representative population-based sample and the use of a clinically validated diagnostic interview to establish a wide range of mental disorders (CIDI 3.0; Haro et al., Reference Haro, Arbabzadeh-Bouchez, Brugha, De Girolamo, Guyer, Jin, Lepine, Mazzi, Reneses and Vilagut2006). However, this study also has limitations. First, the assessment of victimisation and childhood trauma by retrospective self-report may be subject to recall bias. However, there is little evidence that psychopathology is associated with less reliable recollections of victimisation and childhood trauma (Goodman et al., Reference Goodman, Thompson, Weinfurt, Corl, Acker, Mueser and Rosenberg1999; Paivio, Reference Paivio2001; Hardt and Rutter, Reference Hardt and Rutter2004). Second, although face-to-face and telephone interviews remain the golden standard in victimisation research (e.g. Van Dijk et al., Reference Van Dijk, Van Kesteren and Smit2008), both may result in more under-reporting than self-administration (Lynch, Reference Lynch2006). Third, no information about the severity or context of victimisation was available. Fourth, although we adjusted for relevant confounders, it remains possible that the reported associations were influenced by other sources of confounding, such as victimisation at baseline, psychiatric status at the time of follow-up assessment, or the respondent's own violent behaviour. Finally, younger people, people with insufficient mastery of Dutch language, people without a fixed address, and people who were institutionalised were somewhat underrepresented (de Graaf et al., Reference De Graaf, Ten Have and Van Dorsselaer2010). Accordingly, our results are not generalisable to these groups.

Conclusion

This prospective study shows that people with mood, anxiety or substance use disorders are at increased risk of future violent and psychological victimisation. However, the associations with victimisation vary considerably across specific disorders. Clinicians should be aware of the increased risk of any adult victimisation among individuals with alcohol dependence or a history of childhood trauma, and of psychological victimisation in individuals with depressive and anxiety disorders. Interventions that prevent adult (re)victimisation in people at risk are strongly needed. Two recently developed interventions aim to prevent violent victimisation in psychiatric patients by enhancing interpersonal and emotion regulation skills (de Waal et al., Reference De Waal, Kikkert, Blankers, Dekker and Goudriaan2015; Christ et al., Reference Christ, De Waal, Van Schaik, Kikkert, Blankers, Bockting, Beekman and Dekker2018). Importantly, our results show that violence prevention programmes should also target members of the general population with mental disorders. Moreover, these programmes should not only address physical and sexual violence, but also psychological violence.

Supplementary material

The supplementary material for this article can be found at https://doi.org/10.1017/S2045796018000768.

Data

The data on which this manuscript is based are not publicly available. However, data from NEMESIS-2 are available upon request. The Dutch ministry of health financed these data, which can be used freely under certain restrictions, and always under supervision of the principal investigator (PI) of the study. The PI of NEMESIS-2 (Dr Margreet ten Have, co-author of this paper) can be contacted at all times to request data: researchers can submit a research plan, describing its background, research questions, variables to be used in the analyses and an outline of the analyses. If such a request is approved, a written agreement will be signed stating that the data will only be used for addressing the agreed research questions, and not for other purposes.

Author ORCIDs

C. Christ http://orcid.org/0000-0003-0604-551X.

Acknowledgements

The authors thank all participants of the study. The Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2) is conducted by the Netherlands Institute of Mental Health and Addiction (Trimbos Institute) in Utrecht, The Netherlands.

Financial support

NEMESIS-2 is conducted by the Netherlands Institute of Mental Health and Addiction (Trimbos Institute) in Utrecht. Financial support has been received from the Ministry of Health, Welfare and Sport, with supplementary support from The Netherlands Organization for Health Research and Development (ZonMw) and the Genetic Risk and Outcome of Psychosis (GROUP) investigators. Financial support for the current study was also received from the Violence Against Psychiatric Patients program of the Netherlands Organization for Scientific Research (NWO; grant number 432-13-811, awarded to AB, JD, CC, MK and DvS).

The funding sources had no further role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the article for publication.

Conflict of interest

None.

Ethical standards

The authors assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation, and with the Helsinki Declaration of 1975, as revised in 2008.

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Figure 0

Table 1. Sociodemographic characteristics at baseline as correlates of adult victimisation at follow-up in the general population (n  =  5303), in unweighted numbers (n), weighted column percentages (%) and weighted adjusted odds ratios (ORs) with 95% confidence intervals (CIs)

Figure 1

Table 2. Associations between 12-month mental disorders at baseline and adult victimisation at 3-year follow-up (n  =  5171) in unweighted numbers (n) and weighted adjusted odds ratios (ORs) with 95% confidence intervals (CIs)

Figure 2

Table 3. Associations between childhood trauma subtypes at baseline and adult victimisation at 3-year follow-up in the general population (n  =  5171), in unweighted numbers (n) and weighted adjusted odds ratios (ORs) with 95% confidence intervals (CIs)

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