This case study examines a Chinese-Omani cooperation project in the Special Economic Zone at Duqm, Oman (SEZAD) and illustrates how its significance extends beyond the China–Gulf relationship with broader implications for trade and security in the wider region. The Sino-Oman Industrial Park is the major industrial ecosystem that is being developed within the SEZAD and is expected to attract investment of around US$10 billion. Even though the project began as one of the ports along the Maritime Silk Road, it has gained importance mainly due to being located at the strategic transshipment point for goods moving between Africa, Asia, and Europe and providing a crucial node in facilitating global trade and connectivity. This case study first discusses the overall context and considers the investment environment of Oman as well as Oman’s relationship with China. It then concentrates on the SEZAD and highlights several aspects that make this case unique. These include the involvement of multilateral funding, the involvement of Chinese provinces in the development of an overseas industrial park, and issues for China as it strategically invests in a neutral country, Oman.