Data obtained from two experiments were used to identify and describe factors affecting crop loss due to weeds in forage stands. Timothy (Phleum pratense L. ‘Champ′) was established in presence or absence of barley (Hordeum vulgare L. ‘Bruce′), red clover (Trifolium pratense L. ‘Florex′), broadleaf weeds, and grass weeds. Botanical composition, soil water, soil nutrients, light interception, and plant cover were determined 4 and 6 weeks after seeding, and crop yield was determined at periodic forage harvest dates. Principal components analyses permitted the extraction of 12 factors and regression analyses demonstrated that these factors can be used to describe crop yield. Each factor can be estimated either by obtaining the rotated factor scores or by selecting a representative variable that can be substituted for the rotated factor scores in the regression models. The approach described in this paper should be tested with other crops and other weed complexes. It is suggested to use weed density in combination with weed and crop cover data to predict crop loss.