This article presents a bioinspired pneumatic soft actuator designed to mimic the flexo-extension movement of the human finger, with a particular focus on stiffness modulation through granular jamming. Three-chamber geometries – honeycomb, rectangular, and half-round – were evaluated to optimize curvature performance, utilizing Mold Star 15 Slow elastomer for actuator fabrication. Granular jamming, both passive and active, was implemented within the inextensible layer using chia and quinoa grains to enhance stiffness modulation. Experimental results revealed that the honeycomb geometry most closely aligned with the natural index finger trajectory. Stiffness evaluations demonstrated a range of 0–0.47 N/mm/° for quinoa and 0–0.9 N/mm/° for chia. The actuator’s force output increased by 16% for quinoa and 71% for chia compared to the nonjammed configuration. This enhanced performance is particularly beneficial for applications such as hand rehabilitation, where adaptive stiffness and force modulation are critical. Granular jamming, especially with active chia, provided superior adaptability for tasks requiring variable stiffness and resistance, making it a promising candidate for wearable robotic applications in rehabilitation.