Calendar calculations, the process of computing the target day or month, exhibit peculiar differences across languages. In systems like English, calendar labels are largely opaque (Tuesday, August), which invites calculations to rely more heavily on verbal listing. In transparent systems, like Chinese, habitual labeling of calendar terms numerically (Tuesday = Day 2, August = Month 8) facilitates fast numerical operations instead of verbal listing. This study examines the effects that different levels of transparency of the calendar naming system may have on calculations in the speakers’ first and second language. Chinese–English bilinguals were tested alongside English and Chinese controls. Forced-choice calendar calculations (day, month, hour and year) and self-reported strategies were used as tasks to tap into participants’ calculation speed, accuracy and temporal reasoning. In the calculation questions, we manipulated Distance (short/long), Direction (forward/backward), Input (linguistic/numerical) and Boundary (within/across). More complex Month calculations significantly differed across groups while easier day calculations did not. The English group reported reliance on verbal listing while the Chinese and the Bilingual groups preferred numerical reasoning. These findings bring new evidence for linguistic relativity in the form of modulations of calendar processing speed changing as a function of linguistic transparency, input type and task demand.

Global health security in the Biden-Harris Administration has been a dynamic area of engagement, starting with the COVID-19 response, to strengthening and reforming the World Health Organization, to bolstering regional partnerships, and securing financing for pandemic preparedness. Sustained commitment to bilateral, regional, and multilateral cooperation will ensure that the United States stands ready to address any future health challenges.

While we are sympathetic with Stibbard-Hawkes’ approach, we disagree with the proposal to switch to a “cognitively modern” null for all Homo species. We argue in favor of a more evidence-driven approach, inspired by recent debates in comparative cognition. Ultimately, parsing the contributions of different genetic and extra-genetic factors in human evolution is more promising than setting a priori nulls.

Political trust, which signifies the belief in the responsible exercise of power by political institutions, is a fundamental prerequisite for democratic legitimacy. However, even amidst a democratic deficit, the public's trust in the military can remain firm. This study aims to illuminate the prevailing trend and potential factors influencing public trust in the military in Taiwan from 2001 to 2022. The trajectory of trust in Taiwan's military implies fluctuating trust levels in response to the varying intensity of external threats. However, in general, confidence in the armed forces remains higher than that in other political institutions, a trend that is also observed in other nations. The statistical evidence demonstrates substantial support for both cultural and institutional explanations of political trust in the military in Taiwan throughout the initial two decades of the twenty-first century. However, the institutional explanation appears to be more robust than the cultural explanation. Notably, statistical results on trust in the government are consistent across all six survey rounds, with institutional factors showing higher overall significance in the pooled dataset compared to cultural factors, thereby emphasizing the institutional perspective.

Focusing on the cultural history of vocal music in Pahlavi Iran, this article examines the senses in modern Iranian history. As the article shows, the performance of Iranian vocal music became subject to a gendered male and female dichotomy. While this dichotomy did not exist in early Pahlavi Iran, in the early 1950s, a gendered consciousness and language emerged among male musicophilias, eventually separating genres of vocal performance across gender lines. Hence, vocal music known as āvāz became increasingly associated with male performers, while tarāneh and tasnif were increasingly associated with female performers. As the article attempts to show, this gender dichotomy should be contextualized in the broader tension between the sense of vision and sight and disciplined notions of aurality and the body. While the “modern woman's” body permeated the visual domain in the public sphere, the cultural ideals of disciplined aurality and body docility informed the male musicophilias countercultural claims in Pahlavi Iran. Eventually, the latter attempted to challenge the female agency in the public music sphere.

Ragionamenti del mio viaggio intorno al mondo [Chronicles of my voyage around the world] by Francesco Carletti (1573–1636), a Florentine slave merchant and the first private individual to circumnavigate the globe, is a rich source of information about human trafficking from Africa to Spanish America. Carletti writes in detail about his encounters beginning in 1594 in Africa, America, and Asia, including the Philippines, Japan, Macao, Malacca, and Goa, before returning to Europe via the Cape of Good Hope in 1602. But what makes Carletti's record extraordinary are his reports about the sexuality of the peoples he observes in these locations. Following the publications of earlier Italian travel writers Niccolò dei Conti (1395–1469) and Antonio Pigafetta (1491–1531) about the practice of Asian men purposely piercing their genitalia to insert studs and other objects to gratify their female sexual partners, Carletti investigates this phenomenon, concludes its verity, and attributes its existence to the dominance of women's agency in Asia. Carletti's recollections of his voyage are testimony to how exploration during the early modern era catalyzed a transformation in racial discourses and the appreciation of erotic desire in foreign cultures.

What should we do about populism? In recent years, this question has become more urgent as populist leaders and parties have taken center stage in many countries across the globe. No longer a “minor” political phenomenon, populism has forced scholars to grapple with how to address its potential “threat” to “liberal democracy while also harnessing its “corrective” properties (Rovira Kaltwasser 2012). In this debate, the two questions of who “we” are—that is, who should respond—and how to do it often have taken different forms.

Recent Australian public law scholarship has demonstrated an increasing interest in the theme of constitutional values. In the current paper, I seek to clarify the terms of the debate by defending a distinction between (i) constitutional principles, understood as relatively flexible legal norms which rest on text, structure and history and (ii) extra-legal values. My argument is framed initially through a critical discussion of Rosalind Dixon’s proposal for a ‘functionalist’ approach to constitutional interpretation, which ascribes a central place to values in judicial reasoning. The functionalist position, I contend, lacks a sufficiently clear distinction between, on the one hand, constitutional principles as legal norms and, on the other, extra-legal values of political morality. As a consequence, the functionalist appeal to ‘constitutional values’ tends to shift between a relatively modest supplement to purposive approaches to judicial interpretation and a more ambitious proposal for judges to promote ‘normatively attractive’ values. These claims are elaborated and refined through a comparative analysis of German constitutional jurisprudence and a recent example of an appeal to values by the High Court.

There is growing attention to the role of organized labor in maintaining and expanding democratic institutions in the United States. In this article, we investigate the effect of right-to-work laws on electoral democracy in the states. We theorize a series of mechanisms by which labor unions contribute to the maintenance and expansion of democratic institutions, including contributing money to campaigns and influencing the electorate. Right-to-work laws, by limiting labor unions’ ability to raise funds, reduce the strength of these mechanisms and send signals to political elites about the organizational balance of power in their states. Using recent advances in difference-in-differences analysis, we find that right-to-work laws had a substantial negative effect on state-level electoral democracy in recent decades, even net of Republican control of government. Although the difficulty of causal identification in this context warrants caution, the findings speak to the importance of organized labor in shaping democratic institutions.

Social anxiety and depression exacerbate in early adolescence. Maladaptive self-referential processing confers risk for both conditions and can be assessed by the Self-Referent Encoding Task (SRET). Our cross-sectional findings indicated that the SRET-elicited anterior late positive potential (LPP) was uniquely associated with social anxiety symptoms, whereas behavioral SRET scores were uniquely associated with depressive symptoms. Expanding this work, this study investigated whether the SRET-generated behavioral and LPP indices differentially predicted changes of social anxiety or depressive symptoms over time. At baseline, 115 community-dwelling youths (66 girls; Mean age/SD = 11.00/1.16 years) completed an SRET with EEG. Youths reported social anxiety and depressive symptoms at baseline and ∼six and ∼ 12 months later, based on which the intercept and slope of symptoms were estimated as a function of time. A larger anterior LPP in the negative SRET condition uniquely predicted a larger slope (faster increase) of social anxiety (but not depressive) symptoms. Greater positive behavioral SRET scores marginally predicted a smaller slope (slower increase) of depressive (but not social anxiety) symptoms. We provided novel evidence concerning the differential, prospective associations between self-referential processing and changes of social anxiety and depressive symptoms in early adolescence.

The GABA type A receptor (GABAAR) belongs to the family of pentameric ligand-gated ion channels and plays a key role in inhibition in adult mammalian brains. Dysfunction of this macromolecule may lead to epilepsy, anxiety disorders, autism, depression, and schizophrenia. GABAAR is also a target for multiple physiologically and clinically relevant modulators, such as benzodiazepines (BDZs), general anesthetics, and neurosteroids. The first GABAAR structure appeared in 2014, but the past years have brought a particularly abundant surge in structural data for these receptors with various ligands and modulators. Although the open conformation remains elusive, this novel information has pushed the structure–function studies to an unprecedented level. Electrophysiology, mutagenesis, photolabeling, and in silico simulations, guided by novel structural information, shed new light on the molecular mechanisms of receptor functioning. The main goal of this review is to present the current knowledge of GABAAR functional and structural properties. The review begins with an outline of the functional and structural studies of GABAAR, accompanied by some methodological considerations, especially biophysical methods, enabling the reader to follow how major breakthroughs in characterizing GABAAR features have been achieved. The main section provides a comprehensive analysis of the functional significance of specific structural elements in GABAARs. We additionally summarize the current knowledge on the binding sites for major GABAAR modulators, referring to the molecular underpinnings of their action. The final chapter of the review moves beyond examining GABAAR as an isolated macromolecule and describes the interactions of the receptor with other proteins in a broader context of inhibitory plasticity. In the final section, we propose a general conclusion that agonist binding to the orthosteric binding sites appears to rely on local interactions, whereas conformational transitions of bound macromolecule (gating) and allosteric modulation seem to reflect more global phenomena involving vast portions of the macromolecule.

The ‘Viroporin’ family comprises a number of mostly small-sized, integral membrane proteins encoded by animal and plant viruses. Despite their sequence and structural diversity, viroporins share a common functional trend: their capacity to assemble transmembrane channels during the replication cycle of the virus. Their selectivity spectrum ranges from low-pH-activated, unidirectional proton transporters, to size-limited permeating pores allowing passive diffusion of metabolites. Through mechanisms not fully understood, expression of viroporins facilitates virion assembly/release from infected cells, and subverts the cell physiology, contributing to cytopathogenicity. Compounds that interact with viroporins and interfere with their membrane-permeabilizing activity in vitro, are known to inhibit virus production. Moreover, viroporin-defective viruses comprise a source of live attenuated vaccines that prevent infection by notorious human and livestock pathogens. This review dives into the origin and evolution of the viroporin concept, summarizes some of the methodologies used to characterize the structure–function relationships of these important virulence factors, and attempts to classify them on biophysical grounds attending to their mechanisms of ion/solute transport across membranes.

Let R be a ring and let $n\ge 2$. We discuss the question of whether every element in the matrix ring $M_n(R)$ is a product of (additive) commutators $[x,y]=xy-yx$, for $x,y\in M_n(R)$. An example showing that this does not always hold, even when R is commutative, is provided. If, however, R has Bass stable rank one, then under various additional conditions every element in $M_n(R)$ is a product of three commutators. Further, if R is a division ring with infinite center, then every element in $M_n(R)$ is a product of two commutators. If R is a field and $a\in M_n(R)$, then every element in $M_n(R)$ is a sum of elements of the form $[a,x][a,y]$ with $x,y\in M_n(R)$ if and only if the degree of the minimal polynomial of a is greater than $2$.

The target article rightly questions whether the archaeological record is useful for identifying sea changes in hominin cognitive abilities. This commentary suggests an alternative approach of synthesizing findings from primatology, evolutionary developmental biology, and paleoanthropology to formulate hypotheses about cognitive evolution in hominins that lived during the three million years that preceded the record of material culture (the Botanic Age).

By applying narrative inquiry and cartographic reconfiguration of two significantly transformed neighborhoods, Qasr and Heshmatieh, in Tehran, in this study we analyze the practice of remembering within the context of memory politics. We aim to critically examine how residents of these neighborhoods, situated near major state security and military facilities, alter their recollections of the past. Inspired by de Certeau's concepts of strategy and tactics, the analysis seeks to identify the narrative tactics employed by interviewees to interpret the often imposed transformations of the area. Our findings underscore the process of “disremembering” as a hallmark of the transformation, perpetuated through constant “replacements.” Furthermore, they highlight four layers of transformation in the area, discussed within the framework of significant literature on Tehran's spatial transformation.

A paleomagnetic study of basaltic lava flows exposed in the northern Neuquén Cordillera, southernmost Central Andes, along the Antiñir-Copahue fault zone (ACFZ), involved 25 sites of the Cola de Zorro Formation (Pliocene–Early Pleistocene) along two different sections. The sites show exclusive normal polarity, corresponding to the Late Pliocene Gauss chron (3.6–2.6 Ma). The angular standard deviation of virtual geomagnetic poles (VGPs; ASD = 14.8°) is consistent with the expected values from recent geomagnetic models, in opposition to anomalously low dispersion found in previous studies in Pleistocene VGPs of reverse polarity from neighboring areas to our study zone. Mean paleomagnetic directions for Bella Vista (Dec = 0.0°, Inc = −50.0°, α₉₅ = 7.6°, K = 36.7, N = 11) and Río Huaraco sections (Dec = 354.9°, Inc = −57.0°, α₉₅ = 7.5°, K = 55.7, N = 8) do not show tectonic rotation around vertical axes. Combining and regrouping our and previous data by area confirmed the absence of tectonic rotations in the Huaraco-Trohunco block and a statistically significant clockwise rotation of 14.4° ± 10.3° of three adjacent tectonic blocks located south of our study locality in Pleistocene times. These results suggest that strike-slip deformation along some sections of the ACFZ was significant in the Pleistocene structural evolution of this region.