Long associated with the context of territorial disputes on the definition of the Amazon frontiers of the Iberian empires in the late seventeenth and early eighteenth centuries, the map of the Amazon River designed by Jesuit Samuel Fritz is as famous as it is misunderstood. The map is, in fact, quite poorly understood, in both the field of cartographic history, where it would certainly occupy a place of importance, and the nascent field of Amazon social history, where it often serves as a supporting illustration. In fact, even the context in which this map was produced raises disputes that require further study, distinct from those undertaken by nationalist historiographies of the countries that share borders in Amazonia. For example, few studies have been carried out regarding the means of territorial occupation and their inherent conflicts during the first centuries of European colonization of this region. It is precisely for such analysis that the map of Samuel Fritz stands as an important document for historians: more than simply rendering the course of the Amazon River it transmits a political discourse, as does any map, intrinsic to the context in which it was produced.