In the early 1980s, a group of radical African economists working at the Dakar-based Institut Africain de Développement Economique et de Planification (IDEP) were dismissed. Among them were three Ghanaian economists, Tony Obeng, Cadman Atta Mills, and Kwame Amoa, who applied a neocolonial analysis of global political economy to critique international development policies. Although the precise circumstances of their dismissal remain unclear, it was evident that their revolutionary approach to development clashed fundamentally with IDEP’s methods. Inspired by Ghanaian President Kwame Nkrumah’s theory of neocolonialism and the Latin American school of dependency theory, these Pan-African scholars refuted the dominant, anti-political, dehistorical, and simplistic Western explanation of Africa’s underdevelopment and urgently searched for better explanations. Drawing on institutional records, working papers, interviews, memos, and published and unpublished papers, this article centers Africans and African institutions engaged in development thinking in the larger history of economic thought in the 1970s and 1980s.