The fourth marriage of the emperor Leo vi set in motion a complicated series of events involving not only the canonical question of marriage in the Christian life, but also ecclesiastical schism, Church-State relations, and papal ecclesiastical policy. The affair of the tetragamia, centering as it did around the personalities of the emperors Leo vi, Alexander, and Romanus Lecapenus and the patriarchs Nicholas Mysticus and Euthymius, was perhaps the most significant event of early tenth-century Byzantine political and ecclesiastical life.