This article traces the evolutionary record of urbanism at two sites in Myanmar: their transition from late prehistory in c. second to first century BCE to proto-urban and fully urban development at Sri Ksetra and Beikthano by the mid-first millennium CE. The Pyu cities are remarkable because of their spatial continuity, for their early achievements in water control, iron production, ritual and domestic ceramics, brick monumental architecture, rich funerary culture, literacy and adoption of Buddhism on both elite and popular levels. Though the radiocarbon dates for Pyu urbanism are at present earlier, they share many features with other urbanising societies in mainland Southeast Asia, where new chronologies are emerging for social and economic complexity at Dvaravati, Pre-Angkorian and Co Loa sites. The article provides new and specific evidence on the dates and types of contacts between the Pyu, India, and other areas of Southeast Asia to interrogate the meaning of Indianisation in Southeast Asia.