Musculoskeletal disorders remain a leading occupational health challenge in physically demanding sectors such as healthcare, social care, and industry. Exoskeletons – wearable devices designed to mitigate physical strain are increasingly explored as potential solutions; however, factors affecting their adoption in real-world settings remain underexplored. This novel scoping review systematically maps the existing evidence on the application of commercially available exoskeletons within real and simulated work environments, focusing on usage patterns, user experiences, and factors influencing implementation.

Following the Joanna Briggs Institute methodology for scoping reviews, a systematic literature search was conducted across the Web of Science, Scopus, CINAHL, PsycINFO, and MEDLINE, with an initial search in May 2023 and an update in May 2024. Forty-nine papers met the inclusion criteria based on the Population, Concept, and Context (PCC) framework. Data were extracted using a standardized form and synthesized descriptively, thematically, and through content analysis. Results are presented in narrative, tabular, and conceptual map formats.

Exoskeletons were used most frequently in industry (manufacturing) and perioperative care (healthcare). Although, the devices reduced muscle load during repetitive or static tasks, adoption was constrained by discomfort and fit challenges, thermal burden, and limited usability in dynamic settings. Thematic analysis revealed how user experiences were shaped by professional identity, task compatibility, organizational support, and social norms. A conceptual map synthesized sector-specific and cross-sectoral barriers and facilitators.

This review highlights the need for inclusive, context-sensitive, and longitudinal research to support safe, acceptable, and effective exoskeleton adoption and implementation across diverse occupational environments.

Robotic exoskeletons offer the potential to train novel motor skill acquisition and thus aid physical rehabilitation. Our prior work demonstrated that individuals converge to certain kinematic coordinations as they learn a novel task. An upper-limb exoskeleton controller that constrains individuals to this known coordination was also shown to significantly improve straight-line reaching task performance. This paper studies the impact of variations of this controller on novel skill acquisition. We quantify learning under three variations of the intervention (each group with N = 10 participants) against a control group (N = 13). Our results show that introducing any constraint during learning can hinder the learning process, as this alters the task dynamics that lead to success. However, when presented with a personalized constraint, participants still learn. When presented with a task-specific constraint, rather than a personalized one, participants cannot overcome the differences in the training and target task, suggesting exoskeleton-based training interventions should be personalized. The changes in kinematic behaviors during learning further suggest that participants do not have a statistically consistent performance. While participants respond more to exoskeleton intervention, others may not respond in short training sessions, necessitating further analysis of how strong a response can be encouraged. Our findings emphasize the need for further study of the effects of exoskeleton intervention for motor training and the potential need for personalization.

Gait analysis is a fundamental tool in biomechanics and rehabilitation, as it evaluates human movements’ kinematic and kinetic behavior. For this reason, high-precision devices have been developed. However, these require controlled environments, which generates a deficiency in the capacity of studies related to gait analysis in outdoor and indoor scenarios. Therefore, this article describes the development and testing of a wearable system to measure gait cycle kinematic and kinetic parameters. The methodology for the development of the system includes the assembly of modules with commercial surface electromyography (sEMG) sensors and inertial measurement sensors, as well as the use of instrumented insoles with force-resistive sensors, and the design of the software to acquire, process, visualize, and store the data. The system design considers portability, rechargeable battery power supply, wireless communication, acquisition speed suitable for kinematic and kinetic signals, and compact size. Also, it allows simultaneous assessment of sEMG activity, hip and knee joint angles, and plantar pressure distribution, using a wireless connection via Wi-Fi and user datagram protocol for data transmission with a synchronization accuracy of 576 μs, data loss of 0.8%, and autonomy of 167 min of continuous operation, enabling uninterrupted data acquisition for gait analysis. To demonstrate its performance, the system was tested on 10 subjects without any neuromusculoskeletal pathology in indoor and outdoor environments, evaluating relevant parameters that facilitate a comprehensive analysis of gait in various contexts. The system offers a reliable, versatile, and affordable alternative for gait assessment in outdoor and indoor environments.

The manufacturing industry, notably the aeronautics sector, involves tasks presenting risks of low back pain. One of the preventive strategies could be the use of passive back exoskeletons, which have demonstrated benefits during activities involving trunk bending. This study aims to evaluate the effects of four passive back exoskeletons on trunk neuromuscular activity, kinematics, and perceived discomfort during polishing tasks simulated in a laboratory setting. Nineteen participants performed four tasks (two static bending tasks and two load-carrying tasks) without and with two soft (CORFOR and BionicBack) and two rigid (BackX and Laevo FLEX) exoskeletons. The results showed varying effects depending on the tested exoskeleton model, beyond the distinction between rigid and soft designs. Reductions in lumbar erector spinae (LES) neuromuscular activity were observed with Laevo FLEX and CORFOR during static tasks compared to the condition without exoskeleton (8–18%; p < .05). However, reductions in LES muscle activity were not significant during load carrying. Biceps femoris neuromuscular activity was significantly lower in the four tasks when using the Laevo FLEX, with reductions ranging from 8 to 17% (p < .01). The two rigid exoskeletons decreased perceived back discomfort across all tasks (p < .05). Finally, the BionicBack exoskeleton significantly altered participants’ kinematics across all four tasks, reducing both trunk range of motion and average flexion (p < .05). The Laevo FLEX exoskeleton was the only one to significantly reduce both neuromuscular activity and perceived back discomfort, while causing no adverse effects, appearing advantageous when polishing in the aeronautical industry.

Wearable devices placed in or around the ear, often referred to as hearables, are gaining attention as alternative tools for pseudo-continuous health monitoring. Among their several capabilities, hearables are primarily useful for monitoring brain activity electronically via electroencephalography (EEG), enabling noninvasive, long-term recording of neural signals (e.g., from the ear canal). In addition to EEG, hearables can monitor heart rate, oxygen saturation, and temperature, all while maintaining the comfort and discretion of everyday items like earplugs or headphones. This review explores recent progress in combining multiple sensors, leveraging artificial intelligence (AI), and developing novel materials that make hearables more accurate, practical, and comfortable. On-device AI enables real-time, personalized insights that can support therapeutic interventions for neurological disorders like epilepsy. We seek further improvements in design and materials beyond this proof-of-concept, including three-dimensional printing with flexible electrodes while maintaining the unique property of monolithic circuit integration during system printing. That helps devices conform even better to the ear’s anatomy for enhanced comfort and signal quality, while the rigidity of the main structure ensures a highly durable and reliable product suitable for everyday life. In particular, personalization through additive manufacturing enables custom-fitted hearables based on each user’s unique ear canal features, supporting long-term wearability and reliable EEG acquisition. This review also addresses key challenges like motion artifacts and miniaturization, and current strategies to overcome them. Overall, this review highlights hearables as a key emerging technology, especially for EEG-based brain monitoring, offering a personalized, continuous, and noninvasive approach to future healthcare.

Using wearable sensors to evaluate workers’ performance is challenging with existing sensor techniques. It requires detecting not only limb motions but also the onset and offset of specific actions. Commonly used inertial measurement units (IMUs) can be combined with surface electromyography (sEMG) to detect muscular activity. However, sEMG requires skin preparation and careful sensor placement, and can be affected by sweat or motion artifacts. To address these limitations, we used a wearable system combining IMUs and force-sensing resistors (FSRs), where IMUs capture joint kinematics and FSRs detect grasping actions. The system included three IMUs (on the trunk, upper arm, and forearm) and two FSR arrays (on the upper and lower arms). The system was first validated in a laboratory setting against an optical motion capture system with 10 healthy young adults performing isolated upper limb movements and mimicking lifting tasks. The results showed high agreement in joint angle estimation (coefficient of multiple correlation = 0.95 $ \pm $ 0.04), with a maximum root mean square error of 8.7 $ \pm $ 2.92°, and a mean absolute timing error for grasp detection of −0.59 seconds. To evaluate its applicability in real-world scenarios, a pilot in-field test was then conducted with two manufacturing workers (using and not using a passive shoulder exoskeleton) during a repetitive panel-packing task. The test shows highly consistent grasping detection, which allowed segmenting the task with a small variability in task duration (maximum coefficient of variation = 5.16$ \% $). These findings demonstrate the feasibility of using the proposed method in industrial environments to analyze upper limb motion and grasping activity.

Individuals with cerebral palsy (CP) experience significant impairments in lower limb mobility, which severely limit their daily activities and overall quality of life. Robotic exoskeletons have emerged as a cutting-edge solution to assist in the rehabilitation of individuals with CP by improving their motor functions. This systematic review, conducted following PRISMA guidelines, critically evaluates lower limb robotic exoskeletons specifically designed for individuals with CP, focusing on their design, rehabilitation interfaces, and clinical effectiveness. The review includes research papers published between 2010 and 2024, analyzing 30 lower limb exoskeletons reported in 57 papers. We analyze each exoskeleton, focusing on its technological features, user experience, and clinical outcomes. Notably, we identify a trend in which researchers are increasingly adapting exoskeleton functions to the specific needs of individual users, facilitating personalized rehabilitation approaches. Additionally, we highlight critical gaps in current research, such as the lack of sufficient long-term evaluations and studies assessing sustained therapeutic impacts. While ease of use remains crucial for these devices, there is a pressing need for user-friendly designs that promote prolonged engagement and adherence to therapy. This comprehensive review of existing gait rehabilitation exoskeleton technologies aimed to inform future design and application, ultimately contributing to the development of devices that better address the needs of individuals with CP and enhance their motor functions and quality of life.

Industrial upper limb exoskeletons offload the upper limb during overhead tasks to help prevent musculoskeletal disorders to the shoulder. Although numerous studies showed reduced shoulder muscle activity during upper limb exoskeleton use for overhead postures, it remains unknown whether and how upper limb exoskeletons provide support over a large shoulder workspace beyond overhead work. Therefore, this study evaluated the Ottobock Paexo Shoulder over a large shoulder workspace from overhead to hip height with shoulder abduction and adduction. Upper body kinematics, muscle activity, and subjective user feedback were obtained by three-dimensional motion capture, surface EMG, and questionnaires, respectively, and captured while participants performed static and dynamic work tasks with an electric screwdriver. Participants completed these tasks (1) without the exoskeleton, (2) with a disengaged exoskeleton, (3) with moderate exoskeleton support, and (4) with high exoskeleton support. Exoskeleton support reduced deltoid muscle activity (−9 to −24 s%, p ≤ .001) in postures with an abducted shoulder, including nonoverhead postures. Exoskeleton support modestly decreased shoulder flexion (−3 to −5°, p ≤ .001) and increased shoulder abduction (2 to 5°, p ≤ .032), but the movement patterns during the dynamic task were unaffected. Additionally, exoskeleton-related effects increased with increasing support, but the subjective perception of change also increased, and perceived comfort decreased. Our results indicate that the tested exoskeleton provides support beyond overhead work and that there is a trade-off between exoskeleton support and subjective perception. Accordingly, further optimization of user–exoskeleton interaction is warranted for long-term prevention of musculoskeletal disorders in overhead workers.

System uncertainty remains a challenge for effective control of lower extremity exoskeletons, particularly in clinical populations. Adaptive control offers a potential solution by accounting for unknown system characteristics in real time. Here, we introduce the use of Gaussian-based adaptive control (GBAC) in a two-degree-of-freedom (DOF) exoskeleton for an angular position tracking task in the presence of system uncertainty. The mathematical derivation of the implicitly non-Lyapunov adaptation law is presented using Lagrangian mechanics, including a Gaussian kernel regressor and its stable convergence. We then evaluate GBAC performance in a 2-DOF simulation compared with a previously developed robust adaptive backstepping algorithm, Lyapunov-stable Slotine–Li control, and a proportional-integral-derivative (PID) controller. We additionally complete 1-DOF simulations to evaluate the effects of external disturbance and parameter uncertainty on controller performance. Finally, we evaluate GBAC experimentally in our existing 1-DOF knee exoskeleton along with Slotine–Li and PID controllers. The simulation results demonstrate the improved tracking performance and faster convergence of GBAC, especially in the presence of an external disturbance and uncertainty introduced by extra segment length and mass. The experimental results demonstrate similar performance, wherein GBAC and Slotine–Li provide stable tracking in the presence of unmodeled system dynamics; however, convergence time was faster and tracking error was lower for GBAC. Collectively, these results demonstrate that GBAC is an effective adaptive controller in the presence of system uncertainty and therefore warrants further development and investigation for use in flexible joint exoskeleton systems, particularly those designed for pediatric and/or clinical populations that have inherently high uncertainty.

Passive wearable devices are widely used for fitness and have also become fashionable. There is increasing interest in adding functionality, such as knee stability, to these compact devices, which are more convenient for daily wear than separate devices like braces or exoskeletons. This study designed and assessed flexion taping passive wearable devices (FTPW). The design emphasized providing adequate flexion moment capacity and controlling varus/valgus movement to prevent knee injuries. In this research, 20 healthy women performed single leg drop (SLD) and step-up (SU) tests with and without muscle fatigue. Knee joint angle, muscle activation, metabolic cost, and blood flow were measured across FTPW, passive wearable devices without flexion taping (PW), and control shorts (Ctrl). In the SLD test after muscle fatigue, FTPW produced a significantly larger knee flexion angle during landing. In the SU test, before and after fatigue, knee varus angle was notably higher with FTPW. Additionally, FTPW showed reduced knee flexor fatigue, indicated by smaller median frequency shifts, and improved blood flow compared to PW. No significant differences in respiratory exchange ratio were detected among the three conditions. Overall, FTPW demonstrated strong potential to enhance knee kinematics, muscle activation, and blood flow, pointing to benefits for both performance improvement and injury prevention. By delivering focused support in a compact format, FTPW may serve as an innovative passive wearable solution that supports daily movement, comfort, and daily activities. This emphasizes the device’s promise as an alternative to bulkier knee aids, merging style and functionality effectively.

The Myoshirt, an active exosuit, provides gravity compensation for the shoulders. This study evaluated the impact of the Myoshirt on range of motion (ROM), endurance, and activities of daily living (ADLs) performance through tests involving nine participants with varying levels of arm impairments and diverse pathologies. Optical motion capture was used to quantify ROM of the shoulder and elbow joints during isolated movements and functional tasks. Endurance was quantified through a timed isometric shoulder flexion task, and a battery of ADL tasks was used to measure the perceived support of the exosuit, along with changes in movement quality. Feedback and usability insights were gathered with surveys. The Myoshirt did not significantly improve ROM during isolated movements (shoulder flexion, shoulder abduction, and elbow flexion/extension), but during the reaching phase of a functional drinking task elbow extension increased significantly by 13.5% (t = 7.52, p = .002). Participants could also keep their arms elevated 78.7% longer (t = 1.942, p = .047). Patients also reported less perceived difficulty with ADLs while using the device, and a therapist reported improved execution quality. Participants who self-reported severe impairment levels tended to derive greater benefits compared to those with milder impairments. These findings highlight the potential of the Myoshirt as an assistive device, particularly for individuals with severe impairments, while emphasizing the need for further refinement.

Accurate estimation of finger joint stiffness is important in assessing the hand condition of stroke patients and developing effective rehabilitation plans. Recent technological advances have enabled the efficient performance of hand therapy and assessment by estimating joint stiffness using soft actuators. While joint modular soft actuators have enabled cost-effective and personalized stiffness estimation, existing approaches face limitations. A corrective approach based on an analytical model suffers from actuator–finger and inter-actuator interactions, particularly in multi-joint systems. In contrast, a data-driven approach struggles with generalization due to limited availability of labeled data. In this study, we proposed a method for energy conservation-based online tuning of the analytical model using an artificial neural network (ANN) to address these challenges. By analyzing each term in the analytical model, we identified causes of estimation error and introduced correction parameters that satisfy energy balance within the actuator–finger complex. The ANN enhances the analytical model’s adaptability to measurement data, thereby improving estimation accuracy. The results show that our method outperforms the conventional corrective approach and exhibits better generalization potential than the purely data-driven approach. In addition, the method also proved effective in estimating stiffness in human subjects, where errors tend to be larger than in prototype experiments. This study is an essential step toward the realization of personalized rehabilitation.

The adoption of upper limb myoelectric prosthesis is limited by the lack of closed control loop systems. Although the efferent control has already been integrated into these devices, the sensory feedback restoration in the afferent channel still remains an open challenge. Transcutaneous electrical nerve stimulation (TENS) is a promising method for generating somatotopic sensory feedback, allowing the closure of the control loop system. The application of this technique is limited by cumbersome and grid-powered electrical stimulators, making them unsuitable for everyday life, whereas most portable stimulators available on the market are designed for other purposes (e.g., muscular stimulation or pain therapy) and present limited stimulation wave customization. The stimulation devices employed in the literature often produce not fully suitable stimulation parameters and are frequently validated through procedures that do not fully clarify their practical application for sensory feedback restoration. The research aims to present a novel wearable TENS stimulation device (46 g, 62 × 49 × 20 mm) suitable for sensory feedback application. The validation was achieved through a benchtop test and a preliminary analysis on 10 healthy participants comparing the qualities, intensities, and stimulated areas of the sensations elicited by the proposed device and a reference stimulator. The proposed device is capable of delivering charge-balanced stimulation waves over skin-like resistive load and eliciting tingling and vibration sensations with similar intensities compared to the adopted reference.

Cable-driven exoskeletons have recently shown great promise in the rehabilitation of stroke survivors. Numerical modeling/simulation provides a cost- and time-effective approach to fine-tuning design parameters of the exoskeletons, hence reducing the need for expensive and time-consuming experimental trials. This study investigated using a cable-driven lower limb rehabilitation exoskeleton (C-LREX) to correct stroke-impaired gait and track reference healthy trajectories. The impact of different levels of impairment and subject anthropometry variation on the model’s performance was studied. The C-LREX model was successful in assisting the impaired limb to track the reference trajectory in all impaired gait patterns, except for higher impairment levels (>20° range of motion deviation at the hip joint). Subject anthropometry variation did not affect trajectory tracking when the cable routing was scaled to fit the user’s anthropometry. This study confirmed that the C-LREX model could simulate various impaired lower limb gait patterns in the sagittal plane and determine the cable tension requirements needed to correct the impairment. Future work includes expanding the framework to incorporate frontal plane motion and to validate C-LREX performance in assisting biplanar impaired motion.

Lightweight, adjustable, and affordable devices are needed to enable the next generation of effective, wearable adjuncts for rehabilitation. Used at home or in a rehabilitation setting, these devices have the potential to reduce compound pressures on hospitals and social care systems. Despite recent developments in soft wearable robots, many of these devices restrict the range of motion and lack quantitative assessment of moment transfer to the wearer. The decoupled design of our wearable device for upper-limb rehabilitation successfully delivers almost the full range of motion to the user, with a mean maximum flexion angle of 149° (SD = 8.5). In this article, for the first time, we show that in tests involving a wide range of participants, 82% of the moment produced by the actuator is applied to the wearer. This testing of elbow flexion moment transfer supports the effectiveness of the device. This research is a step toward effective pneumatic soft robotic wearable devices that are adaptable to a wide range of users – a necessary prerequisite for their widespread adoption in health care.

In the last two decades, the adoption of exoskeletal devices for the reduction of the biomechanical overload of workers has hugely increased. They allow relief of the biomechanical load of the operator and ensure the operator’s contact with the object without binding its interaction. In this work, the biomechanical and physiological effects on the user wearing upper limb passive exoskeletons have been evaluated to highlight the benefits and possible drawbacks introduced by their use in typical manufacturing tasks. MATE and PAEXO Shoulder passive exoskeletons have been assessed during the execution of different working gestures among static, dynamic, and quasi-static tasks on 16 healthy volunteers. The obtained results confirm that the adoption of such systems significantly impacts the users by reducing the muscular load, increasing endurance, and reducing the perceived effort. Moreover, this analysis pointed out the specific benefits introduced by one exoskeleton with respect to the other according to the specific task. The MATE has the potential to reduce muscle load during the execution of static tasks. Conversely, the PAEXO Shoulder positively impacts the users’ biomechanical performances in dynamic tasks.

Occupational shoulder exoskeletons can relieve workers during strenuous overhead work. Passive solutions are lightweight, robust, and cost-effective, but they can also restrict user movement, have limited support, and cannot dynamically adapt to different working conditions. Semi-active and active systems are still mostly the subject of research, and existing systems are heavy or have limited performance and support. Here, we present a lightweight semi-active exoskeleton for shoulder support that incorporates a novel motorized torque adjustment mechanism that varies the effective lever arm with which a spring applies force to the supporting joint. The mechanism is integrated into lateral structures and can be actuated via Bowden cables with motors located on the user’s back. The technical performance of the system was experimentally characterized in terms of its dynamic support torque profiles at six different support levels. Furthermore, adjustment times and energy consumption were investigated. The system showed plateau-like support torque profiles in the intended working range and could be adjusted from nearly 0 Nm up to 12 Nm of maximum support per arm. Adjustment times varied between 0.5 s for the adjustment of 20% of the total adjustment range and 1.0 s for a full activation/deactivation. Adjustments consumed between 0.1 As and 1.9 As of battery charge, allowing long operating times of up to one working day, using only a small 2 Ah battery. As a result, the exoskeleton provides high performance by combining comparatively high support, rapid motorized support adjustment, and low energy consumption in a lightweight design.

Exoskeletons that make running easier could increase users’ physical activity levels and provide related health benefits. In this paper, we present the design of a portable, powered ankle exoskeleton that assists running and uses lightweight and compact twisted string actuators. It has limited durability at this stage of development, but preliminary results of its power to mass density and potential for reducing the metabolic cost of running are promising. The exoskeleton can provide high peak power of 700 W per leg, 7 times more than prior twisted-string devices, and high peak torques of 43 Nm. Kinetostatic and dynamic models were used to select mass-optimal components, producing a device that weighs 1.8 kg per leg and 2.0 kg in a backpack. We performed preliminary tests on a single participant to evaluate the exoskeleton performance during both treadmill running and outdoor running. The exoskeleton reduced metabolic energy use by 10.8% during treadmill running tests and reduced cost of transport by 7.7% during outdoor running tests compared to running without the device. Unfortunately, the twisted string wore out quickly, lasting an average of 4 min 50 s before breaking. This exoskeleton shows promise for making running easier if string life challenges can be addressed.