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Assumptions in studies of heritability and genotype–phenotype association

Published online by Cambridge University Press:  24 October 2012

Michael B. Miller ,
Colin G. DeYoung  and
Matt McGue
Michael B. Miller
Affiliation:
Department of Psychology, University of Minnesota, Minneapolis, MN 55455. mbmiller@umn.eduhttp://scholar.google.com/citations?user=EV_phq4AAAAJ&hl=encdeyoung@umn.eduhttp://www.tc.umn.edu/~cdeyoung/
Colin G. DeYoung
Affiliation:
Department of Psychology, University of Minnesota, Minneapolis, MN 55455. mbmiller@umn.eduhttp://scholar.google.com/citations?user=EV_phq4AAAAJ&hl=encdeyoung@umn.eduhttp://www.tc.umn.edu/~cdeyoung/
Matt McGue
Affiliation:
Department of Psychology, University of Minnesota, Minneapolis, MN 55455. mbmiller@umn.eduhttp://scholar.google.com/citations?user=EV_phq4AAAAJ&hl=encdeyoung@umn.eduhttp://www.tc.umn.edu/~cdeyoung/ Department of Epidemiology, University of SouthernDenmark, DK-5000 Odense C, Denmark. mcgue001@umn.eduhttp://www.psych.umn.edu/people/faculty/mcgue.htm
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Abstract

Charney's dismissal of well-established methods in behavioral genetic research is misguided. He claims that studies of heritability and genetic association depend for their validity on six assumptions, but he cites no sources to support this claim. We explain why none of the six assumptions is strictly necessary for the utility of either method of genetic analysis.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 35 , Issue 5 , October 2012 , pp. 372 - 373
Copyright
Copyright © Cambridge University Press 2012 

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