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If treatments or vaccines for COVID-19 are scarce, should patients pre-existing disabilities be relevant to allocating those interventions? In allocating scarce life-sustaining treatments, some crisis standards of care have explicitly deprioritized or even categorically excluded individuals with underlying conditions that are understood to limit probability of survival, life expectancy or the quality of life. Others have used scoring systems that may work to the disadvantage of people with certain disabilities. All of these systems have faced opposition from disability rights advocates. But advocates have not opposed proposals to prioritize individuals with pre-existing disabilities for receipt of a vaccine. This chapter offers a dialogue on the legal and ethical questions presented by the impact of allocation policies on individuals with disabilities. One of the authors has served as counsel to advocacy organizations that have challenged disability-based crisis standards of care; the other author has defended evidence-based use of disability in allocating scarce life-sustaining treatments.
This paper investigates how the numerosity bias influences individuals’ allocation of resources between themselves and others, using the backdrop of the traditional dictator game. Across four studies including both hypothetical and real exchanges of money, we show that the form of the numerical value representing the quantity of the resource (e.g., $20 vs 2000 cents) systematically biases the decision-maker to perceive the quantity s/he is thinking of allocating as being “less than adequate” or “more than adequate”. Essentially, such a biased perception of adequacy with respect to the quantity of the resource consequently influences the decision-maker’s final allocation decision. We attribute this systematic bias to the “numerosity” of the resource. We find that bigger numerical values representing quantity (e.g., 2000 cents) bias decision-makers to over-infer the quantity, thus inducing them to allocate less to the entities they are focusing on.
The analysis in this chapter proceeds from the assumption that shared responsibility for a breach of a shared obligation has been established and focuses on the content of that responsibility. In the case that secondary obligations of reparation or cessation arise, what can be claimed from which responsible actor, and to what extent is this influenced by the fact that the underlying primary obligation is shared? And if injured parties wish to effectuate these secondary obligations through international adjudication, are there any obstacles to the claiming of cessation and reparation? It will ultimately be argued that conceiving of the content of shared responsibility as consisting of shared obligations incumbent on all responsible actors can help untangle which of the responsible states or international organizations is bound to do what in terms of cessation and reparation. In this context, the distinction between divisible and indivisible shared obligations has an important role to play. After all, determining whether responsible actors are each bound only to their own share of cessation or reparation or whether, alternatively, all of them become bound to achieve a common result has direct implications for what can be claimed from whom.
Chapter 9 explores the many situations in which new IP is developed under a licensing or other agreement, and how that IP is owned and licensed. Attention is given both to licensee developments (improvements and derivative works of licensed rights), which may be subject to grantback and license-back arrangements (Kennedy v. NJDA) and new IP developed by a licensor under a services arrangement (e.g., commissioned works, customizations) (IXL v. AdOutlet) and the incorporation of third party components in developed technologies. The chapter also addresses the complex issues that arise from joint development of IP, including treatment of foreground, background and sideground IP, and how IP is used in the context of joint ventures (Pav-Saver v. Vasso). The chapter concludes with a discussion of the allocation of responsibility for IP management, maintenance and prosecution.
Access and allocation firmly ground the concept of human security in the larger context of social justice, posing serious challenges for equitable earth system governance.The focus on capabilities brings together a range of ideas addressed inadequately in traditional approaches to the economics of welfare. The capabilities approach highlights the importance of real freedoms in the assessment of persons’ relative level of advantage, promoting a more realistic balance of materialistic and non-materialistic factors in evaluating human welfare and a concern for the distribution of substantive opportunities within society.Research on access to and allocation of environmental resources in a deliberative system of democratic governance builds on and extends an existing limited research literature on the implications of deliberative democratic practices for environmental justice policy and governance.More equitable access to and allocation of environmental “goods” should be a focus for a next generation of environmental research characterized by improved normative understanding as well as more meaningful and reflexive potential for sustainability transformation.
The question of how to tax multinational companies that operate highly digitalised business models is one of the most contested areas of international taxation. The tax paid in the jurisdictions in which these companies operate has not kept pace with their immense growth and the OECD has proposed a new international tax compromise that will allocate taxing rights to market jurisdictions and remove the need to have a physical presence in the taxing jurisdictions in order to sustain taxability. In this work, Craig Elliffe explains the problems with the existing international tax system and its inability to respond to challenges posed by digitalised companies. In addition to looking at how the new international tax rules will work, Elliffe assesses their likely effectiveness and highlights features that are likely to endure in the next waves of international tax reform.
Single nucleotide polymorphisms (SNPs) able to describe population differences can be used for important applications in livestock, including breed assignment of individual animals, authentication of mono-breed products and parentage verification among several other applications. To identify the most discriminating SNPs among thousands of markers in the available commercial SNP chip tools, several methods have been used. Random forest (RF) is a machine learning technique that has been proposed for this purpose. In this study, we used RF to analyse PorcineSNP60 BeadChip array genotyping data obtained from a total of 2737 pigs of 7 Italian pig breeds (3 cosmopolitan-derived breeds: Italian Large White, Italian Duroc and Italian Landrace, and 4 autochthonous breeds: Apulo-Calabrese, Casertana, Cinta Senese and Nero Siciliano) to identify breed informative and reduced SNP panels using the mean decrease in the Gini Index and the Mean Decrease in Accuracy parameters with stability evaluation. Other reduced informative SNP panels were obtained using Delta, Fixation index and principal component analysis statistics, and their performances were compared with those obtained using the RF-defined panels using the RF classification method and its derived Out Of Bag rates and correct prediction proportions. Therefore, the performances of a total of six reduced panels were evaluated. The correct assignment of the animals to its breed was close to 100% for all tested approaches. Porcine chromosome 8 harboured the largest number of selected SNPs across all panels. Many SNPs were included in genomic regions in which previous studies identified signatures of selection or genes (e.g. ESR1, KITL and LCORL) that could contribute to explain, at least in part, phenotypically or economically relevant traits that might differentiate cosmopolitan and autochthonous pig breeds. Random forest used as preselection statistics highlighted informative SNPs that were not the same as those identified by other methods. This might be due to specific features of this machine learning methodology. It will be interesting to explore if the adaptation of RF methods for the identification of selection signature regions could be able to describe population-specific features that are not captured by other approaches.
Tropical bamboos persist in a wide range of light conditions and quickly respond to changes in light availability. However, the mechanisms underpinning this ability remain unknown. In order to test the hypothesis that the modular and hollow culm architecture of bamboos explains their performance in a wide range of light environments, we determined the allometric relationships of two dominant bamboo species of the upper hill dipterocarp forests of Malaysia, Gigantochloa ligulata (n = 29) and Schizostachyum grande (n = 25), via destructive sampling. We also monitored biomass turnover of bamboos and woody trees in 24 permanent plots (1.92 ha in total) over a one-year period. Compared with woody trees, bamboo culms attained 1.5 times the height and their clumps supported four times as much total leaf area at the same above-ground biomass. In addition, at a given height, bamboo clumps had six times larger crown projection area than trees while having a similar amount of total leaf area per unit of crown projection area. Finally, bamboos’ biomass turnover rate was three times higher than trees, and G. ligulata increased its specific rate of biomass increase after canopy disturbance, while trees decreased. We conclude that the unique architecture of bamboos allows them to persist under closed forest canopy light conditions and to respond to gap formation via high biomass turnover rate.
Crop interference and weed-competitive cultivars are a component of integrated weed management, but their use requires understanding the extent to which rice can interfere with weed growth and how weeds may respond to rice interference. Growth of blistering ammannia was studied in a screen house by growing it alone or with rice seeded in rows (20 cm) or broadcast at the rate of 25 and 75 kg ha−1. The growth of blistering ammannia was similar whether grown with rice seeding rates of 25 or 75 kg ha−1 or with broadcast or row-seeded rice, suggesting that the weed is a weak competitor if rice is planted uniformly. Rice interference greatly reduced the number of blistering ammannia leaves and leaf, stem, total shoot, and root biomass. However, the weed showed the ability to reduce the effects of rice interference by increasing leaf and stem biomass in the upper half of the plant, and increasing specific stem length. At 11 wk after planting, blistering ammannia had 71 to 80% leaf biomass in the upper half of the plant when grown with rice interference compared with only 29% when grown without rice interference. Despite such plasticity, blistering ammannia shoot and root biomass at final harvest decreased by 94 to 99% when grown with rice compared with its biomass without crop interference. These results suggest that blistering ammannia is a poor competitor and uniform rice density could be very effective in suppressing blistering ammannia in direct-seeded rice systems.
For the prevention and control of newly emergent or sudden infectious diseases, we built an on-site, modularized prevention and control system and tested the equipment by using the clustering analysis method. On the basis of this system, we propose a modular equipment allocation method and 4 applications of this method for different types of infectious disease prevention and control. This will help to improve the efficiency and productivity of anti-epidemic emergency forces and will provide strong technical support for implementing more universal and serialized equipment in China. (Disaster Med Public Health Preparedness. 2017;11:375–382)
In September 2014, a healthy male child was born in Sweden following a successful uterine transplantation (UTx). The event brought hope to many women without functional uteruses around the world. Having a child with a transplanted uterus is now possible, and as knowledge of the procedure proliferates and interest in UTx grows, it is important to begin thinking about how a scarce supply of uteruses will be allocated. This article represents a first discussion of the range of factors that must be considered in answering the allocation question. The primary issues addressed are (1) the motivation to seek treatment, (2) allocation by age, (3) child-rearing capacity, and (4) the amount of infertility treatment required. A set of eligibility and ranking criteria are presented. These criteria are not exhaustive but are intended to spark discussion about how uteruses can be allocated in a just manner.
Juvenile tropical trees grow from the shaded understorey to the high-light conditions of the canopy, but actual height growth trajectories towards the canopy remain unknown. Although height growth is the determining factor for reaching the canopy, investment in diameter growth is needed to sustain mechanical stability. We quantified variation in long-term juvenile tree growth patterns in diameter and height within three Bolivian moist forest species, and evaluated whether diameter growth and height growth were related. We reconstructed lifetime growth in diameter and height for 21–27 juvenile trees per species by measuring tree rings at various heights in the stem. Growth in diameter and height strongly varied among and within tree species. The light-demanding species Cedrelinga cateniformis needed just 6–19 y to reach a height of 3 m, while the more shade-tolerant species Clarisia racemosa and Peltogyne cf. heterophylla needed 8–39 y and 13–43 y, respectively. Diameter growth and height growth were not, or just weakly, positively related, and trees of the same height displayed a wide range in stem diameter. Our results indicate that trees of all three species shifted investment in diameter growth and height growth over time, most likely in response to variation in light levels.
Suggested methods to reduce farm financial stress have included interest rate buy-downs and debt forgiveness. This study develops a method to estimate the proportion of individual farm financial stress attributable to an income problem, a leverage problem, and an interest rate problem. Of the Kansas Farm Management Association farms with a financial problem, 30 percent of the total financial problem is caused by an interest rate problem, 28 percent by a leverage problem, and 42 percent by an income problem. A reduction of leverage or interest rate to the level attained by the average nonstressed farms would make 31 percent and 32 percent of the stressed farms profitable, respectively. Therefore, in the short run, an interest rate buy-down or a debt reduction would be equally effective.
Nous considérons une prise de contrôle dans laquelle les motivations des repreneurs potentiels sont multiples et étudions I’impact du degré d’affiliation de leurs évaluations sur la stratégie optimale. Nous montrons que cet impact dépend du rapport des dotations initiales. Nous trouvons que lorsque les dotations initiales sont symétriques, la stratégie optimale des enchérisseurs est indépendante du degré d’affiliation de leurs évaluations. En revanche, lorsque les dotations initiales sont asymétriques, cet impact dépend du niveau du signal privé de l’enchérisseur. Si les acqueréurs potentiels surenchérissent en présence de dotations initiales, l’étendue de la surenchére décroît avec l’augmentation du degré d’affiliation lorsque le signal privé est inférieur un certain seuil. L’agressivité des enchérisseurs profite à la firme cible dont le revenu espéré augmente avec le degré d’affiliation des évaluations.
The implementation of an international programme for reducing carbon emissions from deforestation and degradation (REDD) can help to mitigate climate change and bring numerous benefits to environmental conservation. Information on land change modelling and carbon mapping can contribute to quantify future carbon emissions from deforestation. However limitations in data availability and technical capabilities may constitute an obstacle for countries interested in participating in the REDD programme. This paper evaluates the influence of quantity and allocation of mapped carbon stocks and expected deforestation on the prediction of carbon emissions from deforestation. The paper introduces the conceptual space where quantity and allocation are involved in predicting carbon emissions, and then uses the concepts to predict carbon emissions in the Brazilian Amazon, using previously published information about carbon mapping and deforestation modelling. Results showed that variation in quantity of carbon among carbon maps was the most influential component of uncertainty, followed by quantity of predicted deforestation. Spatial allocation of carbon within carbon maps was less influential than quantity of carbon in the maps. For most of the carbon maps, spatial allocation of deforestation had a minor but variable effect on the prediction of carbon emissions relative to the other components. The influence of spatial carbon allocation reaches its maximum when 50% of the initial forest area is deforested. The method can be applied to other case studies to evaluate the interacting effects of quantity and allocation of carbon with future deforestation on the prediction of carbon emissions from deforestation.
Let ξ be a random measure on a locally compact second countable topological group, and let X be a random element in a measurable space on which the group acts. In the compact case we give a natural definition of the concept that the origin is a typical location for X in the mass of ξ, and prove that when this holds, the same is true on sets placed uniformly at random around the origin. This new result motivates an extension of the concept of typicality to the locally compact case where it coincides with the concept of mass-stationarity. We describe recent developments in Palm theory where these ideas play a central role.
In an epidemic situation or large-scale disaster, medical and human resources may be stretched to the point of exhaustion. Appropriate planning must incorporate plans of action that minimize public health morbidity and mortality while maximizing the appropriate use of medical and human healthcare resources. While the current novel H1N1 influenza has spread throughout the world, the severity of this strain of influenza appears to be relatively less virulent and lethal compared to the 1918 influenza pandemic.However, the presence of this new influenza strain has reignited interest in pandemic planning.
Amongst other necessary resources needed to combat pandemic influenza, a major medical resource concern is the limited number of mechanical ventilators that would be available to be used to treat ill patients. Recent reported cases of avian influenza suggest that mechanical ventilation will be required for the successful recovery of many individuals ill with this strain of virus. However, should the need for ventilators exceed the number of available machines, how will care providers make the difficult ethical decisions as to who should be placed or who should remain on these machines as more influenza patients arrive in need of care?
This paper presents a decision-making model for clinicians that is based upon the bioethical principles of beneficence and justice. The model begins with the basic assumptions of triage and progresses into a useful algorithm based upon utilitarian principles. The model is intended to be used as a guide for clinicians in making decisions about the allocation of scarce resources in a just manner and to serve as an impetus for institutions to create or adapt plans to address resource allocation issues should the need arise.
The decision to declare a major incident (MI) is not one to be taken lightly, but a delay in doing so may have dire consequences. The aim of this study was to ascertain what factors make specialists from a variety of pro-fessional backgrounds in the United Kingdom determine from an initial visu-al assessment of a scene that a MI should be declared.
Methods:
Participants were presented with three different scenarios, which were presented pictorially. Their responses were noted.
Results:
One hundred seventy-eight professionals took part in this study. For Scenario 1 (a road traffic incident), 101 (57%) declared a MI. For a coach rollover in Scenario 2, a MI was declared by 82 (46%) people, and a MI was declared by 156 (87%) for a rail crash in Scenario 3.
Forty-six participants had attended a MI previously.The results for declar-ing a MI in this group were: (1) Scenario 1, 25 (54%); (2) Scenario 2, 25 (54%); and (3) Scenario 3, 44 (96%). Of this group, 44 had previously had training before experiencing the MI. Those who had >10 years of service in emergency services were more likely to declare a MI in Scenario 2 and 3.
Conclusions:
The main problem with the existing system is the interpreta-tion and subjective nature of the word “major”. Specialists incorporate many individual factors into using the word. Future research should focus on the development of a system tied to more objective analysis.
Above- and below-ground morphology of seedlings (up to 98 cm in height) were compared by allometric
analyses in tropical heath forest and peat-swamp forest in Central Kalimantan. Thirteen abundant species were selected,
including two species found in both forests. In above-ground morphology, heath forest seedlings invested more in leaf
mass, while peat-swamp forest seedlings invested more in stem mass, stem height, crown area and leaf area. In
below-ground morphology, heath forest seedlings invested more in root mass and depth, while peat-swamp forest
seedlings invested more in lateral development of the root system. Both specific leaf area and area per leaf of heath
forest seedlings were lower than those of peat-swamp forest seedlings. This differentiation in seedling morphology
between forest types was evident as a plastic response in the two shared species. Heath forest seedlings on coarse-textured bleached sand with low water retention suffer occasional drought whereas peat-swamp forest seedlings on
waterlogged peat rarely experience drought. We concluded that seasonal water limitation brought about the convergence in seedling morphology within heath forest because average understorey irradiances and soil nutrient concentration were assumed to be similarly low in both forests.