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Volume 71 - November 2012

Contents

Page 8 of 17

Front Cover (OFC, IFC) and matter

  • PNS volume 71 issue 4 Cover and Front matter

  • Published online by Cambridge University Press:
    26 October 2012, pp. f1-f7
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Postgraduate Symposium

Conference on ‘Nutrition and health: cell to community’

  • The influence of maternal protein nutrition on offspring development and metabolism: the role of glucocorticoids

  • K. Almond, P. Bikker, M. Lomax, M. E. Symonds, A. Mostyn
  • Published online by Cambridge University Press:
    29 November 2011, pp. 198-203
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  • The consequences of sub-optimal nutrition through alterations in the macronutrient content of the maternal diet will not simply be reflected in altered neonatal body composition and increased mortality, but are likely to continue into adulthood and confer greater risk of metabolic disease. One mechanism linking manipulations of the maternal environment to an increased risk of later disease is enhanced fetal exposure to glucocorticoids (GC). Tissue sensitivity to cortisol is regulated, in part, by the GC receptor and 11β-hydroxysteroid dehydrogenase (11β-HSD) types 1 and 2. Several studies have shown the effects of maternal undernutrition, particularly low-protein diets, on the programming of GC action in the offspring; however, dietary excess is far more characteristic of the diets consumed by contemporary pregnant women. This study investigated the programming effects of moderate protein supplementation in pigs throughout pregnancy. We have demonstrated an up-regulation of genes involved in GC sensitivity, such as GC receptor and 11β-HSD, in the liver, but have yet to detect any other significant changes in these piglets, with no differences observed in body weight or composition. This increase in GC sensitivity was similar to the programming effects observed following maternal protein restriction or global undernutrition during pregnancy.

Abstract

  • Eating behaviours in obese and lean women with polycystic ovary syndrome

  • Y. M. Jeanes, J. Hodgson, N. Saunders, L. Gibson, K. Hart
  • Published online by Cambridge University Press:
    12 April 2013, E237
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  • Food, physical activity and climate change perspectives in relationship to allotment ownership

  • A. M. Hunt, C. Burek, B. Ellahi
  • Published online by Cambridge University Press:
    26 April 2012, E23
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Back Cover (IBC, OBC) and matter

  • PNS volume 71 issue 4 Cover and Back matter

  • Published online by Cambridge University Press:
    26 October 2012, pp. b1-b6
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Abstract

Front Cover (OFC, IFC) and matter

  • PNS volume 71 issue 1 Cover and Front matter

  • Published online by Cambridge University Press:
    26 January 2012, pp. f1-f7
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Abstract

Back Cover (IBC, OBC) and matter

  • PNS volume 71 issue 1 Cover and Back matter

  • Published online by Cambridge University Press:
    26 January 2012, pp. b1-b9
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Abstract

  • Statin prescription and dietary imprudence

  • S. F. McAleer, C. E. Neville, M. C. McKinley, J. V. Woodside, M. A. Tully, M. E. Cupples
  • Published online by Cambridge University Press:
    12 April 2013, E240
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Page 8 of 17