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Numerous studies have been conducted to comprehend the economic importance of market participation for producers. However, a significant gap remains, particularly in Central Asia. This study assesses market participation drivers for Kyrgyzstan’s milk producers using the Life in Kyrgyzstan dataset, encompassing a comprehensive nationwide farm-level survey. Findings reveal that household assets boost market entry and sales volume, whereas distance from markets discourages participation but can increase sales for active sellers, reflecting transportation cost strategies. The insights inform policy interventions benefiting rural small-scale milk producers in Central Asian countries that share similar cultural backgrounds.
Dilated cardiomyopathy is an expected manifestation and common cause of death in patients with Duchenne muscular dystrophy. We present an unusually rapid progression of cardiomyopathy in a boy with Duchenne muscular dystrophy. Expanded genetic testing revealed a contiguous Xp21 deletion involving dystrophin and XK genes, responsible for Duchenne muscular dystrophy and McLeod neuroacanthocytosis syndrome, respectively, resulting in a more severe cardiac phenotype.
Low- and middle-income countries (LMICs) bear a disproportionate burden of mental illness, with limited access to biomedical care. This study examined pathways to care for psychosis in rural Uganda, exploring factors influencing treatment choices.
Methods
We conducted a mixed-methods study in Buyende District, Uganda, involving 67 in-depth interviews and 4 focus group discussions (data collection continued until thematic saturation was reached) with individuals with psychotic disorders, family members, and local leaders. Structured questionnaires were administered to 41 individuals with psychotic disorders.
Results
Three main themes emerged: (1) Positive attitudes towards biomedical providers, (2) Barriers to accessing biomedical care (3) Perceived etiologies of mental illness that influenced care-seeking behaviors. While 81% of participants eventually accessed biomedical care, the median time to first biomedical contact was 52 days, compared to 7 days for any care modality.
Conclusions
Despite a preference for biomedical care, structural barriers and diverse illness perceptions led many to seek pluralistic care pathways. Enhancing access to biomedical services and integrating traditional and faith healers could improve mental health outcomes in rural Uganda.
Across the twentieth century, hundreds of women worked as nurses, cooks, cleaners, and teachers on Mexico’s railroads. They have been overlooked in histories of the railroads and Mexican industrialization more broadly, their limited number perhaps suggesting that their work is not of analytical importance in understanding processes of economic development and class formation. On the contrary, these women’s work constituted many of the most coveted labor rights of the postrevolutionary railroad workforce, itself a symbolic vanguard of Mexico’s working class and one of the most important beneficiaries of the expansion of social and economic rights ushered in by the Mexican Revolution. The gendered division of labor characteristic of the railroads was neither accidental nor insignificant. Railroads used the feminization of the work of social reproduction to write off structural failures and predictable shortcomings in welfare provision as failures of femininity. Women became scapegoats for the consistent violation of workers’ rights through underfunding and understaffing. In tracing this process, the article models a historiographical and methodological intervention with broader relevance. It suggests that the social and labor rights that expanded around the world in the late-nineteenth and early-twentieth centuries must be studied not only from the vantage of legal or political history, but as themselves questions of social and labor history. Making these rights real depended on socially reproductive work that has often been marginal in accounts of industrialization and economic development. It is impossible to understand the political economy of social and economic rights without understanding women’s work.
Aqueous suspensions of cornstarch abruptly increase their viscosity on raising either shear rate or stress, and display the formation of large-amplitude waves when flowing down inclined channels. The two features have been recently connected using constitutive models designed to describe discontinuous shear thickening. By including time-dependent relaxation and spatial diffusion of the frictional contact density responsible for shear thickening, an analysis of steady sheet flow and its linear stability is presented. The inclusion of such effects is motivated by the need to avoid an ill-posed mathematical problem in thin-film theory and the resulting failure to select any preferred wavelength for unstable linear waves. Relaxation, in particular, eliminates an ultraviolet catastrophe in the spectrum of unstable waves and furnishes a preferred wavelength at which growth is maximized. The nonlinear dynamics of the unstable waves is briefly explored. It is found that the linear instability saturates once disturbances reach finite amplitude, creating steadily propagating nonlinear waves. These waves take the form of a series of steep, shear-thickened steps that translate relatively slowly in comparison with the mean flow.
Second primary breast cancers are among the most common risks to female patients who have received radiotherapy for mediastinal lymphoma.
This study aims to audit breast dose in women who received mediastinal radiotherapy for lymphoma and compare the combined dose parameter values measured to those in the literature.
Methods:
Twenty-three patient datasets from 2017 to 2021 were obtained. Inclusion criteria, such as female gender and 30Gy prescription dose, were applied. Target volumes were delineated using involved site radiotherapy and planned on Eclipse (Varian, Palo Alto, CA) using either fixed field or VMAT. Breast contours were retrospectively outlined according to RTOG/EORTC guidance and descriptive statistics were used to compare findings to those from the literature.
Results:
Differences were found in V4gy, V5Gy and mean dose compared to the literature with mean dose being 2Gy in the literature and 4Gy in this audit.
Conclusions:
Breast dose parameter values between patients in this study vary due to multiple factors. These include the treatment delivery method used and the position of the treatment field in relation to the location of breast tissue. Mean dose and V4% and V5% to breast tissue found in this study differ from that found in the literature. This study highlights the importance of accurate contouring and optimising breast tissue when possible.
Rapid advancements in high-energy ultrafast lasers and free electron lasers have made it possible to obtain extreme physical conditions in the laboratory, which lays the foundation for investigating the interaction between light and matter and probing ultrafast dynamic processes. High temporal resolution is a prerequisite for realizing the value of these large-scale facilities. Here, we propose a new method that has the potential to enable the various subsystems of large scientific facilities to work together well, and the measurement accuracy and synchronization precision of timing jitter are greatly improved by combining a balanced optical cross-correlator (BOC) with near-field interferometry technology. Initially, we compressed a 0.8 ps laser pulse to 95 fs, which not only improved the measurement accuracy by 3.6 times but also increased the BOC synchronization precision from 8.3 fs root-mean-square (RMS) to 1.12 fs RMS. Subsequently, we successfully compensated the phase drift between the laser pulses to 189 as RMS by using the BOC for pre-correction and near-field interferometry technology for fine compensation. This method realizes the measurement and correction of the timing jitter of ps-level lasers with as-level accuracy, and has the potential to promote ultrafast dynamics detection and pump–probe experiments.
The knowledge of students’ quality of life and post-traumatic stress disorder levels, investigation of the relationship between them, and taking measures are essential in terms of guiding the necessary interventions. This study was conducted to determine the quality of life and post-traumatic stress disorder levels of midwifery students experiencing an earthquake.
Methods
This descriptive and correlational study was conducted with 363 midwifery students who had experienced the Kahramanmaras, Türkiye earthquake. Data were obtained using a Descriptive Information Form, the PTSD-Brief Scale, and the World Health Organization Quality of Life Scale (WHOQOL-BREF).
Results
The rate of post-traumatic stress disorder in the sample studied (n = 363), which consisted of midwifery students who would work in the field of health, was 21.5% 2 months after the earthquake. The multiple linear regression analysis indicated that factors predicting post-traumatic stress disorder following the earthquake were quality of life score related to physical and environmental domains, damage status of the house, presence of family history of depression, and smoking status.
Conclusions
This study, which was conducted 2 months following the earthquakes, showed that living spaces had an impact on the occurrence of post-traumatic stress disorder symptoms.
We present an experimental study on the drag reduction by polymers in Taylor–Couette turbulence at Reynolds numbers ($Re$) ranging from $4\times 10^3$ to $2.5\times 10^4$. In this $Re$ regime, the Taylor vortex is present and accounts for more than 50 % of the total angular velocity flux. Polyacrylamide polymers with two different average molecular weights are used. It is found that the drag reduction rate increases with polymer concentration and approaches the maximum drag reduction (MDR) limit. At MDR, the friction factor follows the $-0.58$ scaling, i.e. $C_f \sim Re^{-0.58}$, similar to channel/pipe flows. However, the drag reduction rate is about $20\,\%$ at MDR, which is much lower than that in channel/pipe flows at comparable $Re$. We also find that the Reynolds shear stress does not vanish and the slope of the mean azimuthal velocity profile in the logarithmic layer remains unchanged at MDR. These behaviours are reminiscent of the low drag reduction regime reported in channel flow (Warholic et al., Exp. Fluids, vol. 27, no. 5, 1999, pp. 461–472). We reveal that the lower drag reduction rate originates from the fact that polymers strongly suppress the turbulent flow while only slightly weaken the mean Taylor vortex. We further show that polymers steady the velocity boundary layer and suppress the small-scale Görtler vortices in the near-wall region. The former effect reduces the emission rate of both intense fast and slow plumes detached from the boundary layer, resulting in less flux transport from the inner cylinder to the outer one and reduces energy input into the bulk turbulent flow. Our results suggest that in turbulent flows, where secondary flow structures are statistically persistent and dominate the global transport properties of the system, the drag reduction efficiency of polymer additives is significantly diminished.
We model transient mushy-layer growth for a binary alloy solidifying from a cooled boundary, characterising the impact of liquid composition and thermal growth conditions on the mush porosity and growth rate. We consider cooling from a perfectly conducting isothermal boundary, and from an imperfectly conducting boundary governed by a linearised thermal boundary condition. For an isothermal boundary we characterise different growth regimes depending on a concentration ratio, which can also be viewed as characterising the ratio of composition-dependent freezing point depression versus the temperature difference across the mushy layer. Large concentration ratio leads to high porosity throughout the mushy layer and an asymptotically simplified model for growth with an effective thermal diffusivity accounting for latent heat release from internal solidification. Low concentration ratio leads to low porosity throughout most of the mushy layer, except for a high-porosity boundary layer localised near the mush–liquid interface. We identify scalings for the boundary-layer thickness and mush growth rate. An imperfectly conducting boundary leads to an initial lag in the onset of solidification, followed by an adjustment period, before asymptoting to the perfectly conducting state at large time. We develop asymptotic solutions for large concentration ratio and large effective heat capacity, and characterise the mush structure, growth rate and transition times between the regimes. For low concentration ratio the high porosity zone spans the full mush depth at early times, before localising near the mush–liquid interface at later times. Such variation of porosity has important implications for the properties and biological habitability of mushy sea ice.
Studies have shown that some covertly conscious brain-injured patients, who are behaviorally unresponsive, can reply to simple questions via neuronal responses. Given the possibility of such neuronal responses, Andrew Peterson et al. have argued that there is warrant for some covertly conscious patients being included in low-stakes medical decisions using neuronal responses, which could protect and enhance their autonomy. The justification for giving credence to alleged neuronal responses must be analyzed from various perspectives, including neurology, bioethics, law, and as we suggest, philosophy of mind. In this article, we analyze the warrant for giving credence to neuronal responses from two different views in philosophy of mind. We consider how nonreductive physicalism’s causal exclusion problem elicits doubt about interpreting neural activity as indicating a conscious response. By contrast, such an interpretation is supported by the mind-body powers model of neural correlates of consciousness inspired by hylomorphism.