No significant relationships.

Mothers of terminally ill children experience chronic stress that can lead to physical and emotional exhaustion. A better understanding of their experiences, resources, and vulnerabilities can help plan psychological interventions.

The research is aimed to study mothers’ appraisals of their life situation related to the child’s terminal illness and their coping strategies.

Participants: 21 women (aged 26-49) whose children were patients at the hospice. Women answered a set of open-ended questions and completed questionnaires: “Appraisal Criteria of the Difficulty of a Life Situation”, “Types of Orientations in Difficult Situation”, “Ways of Coping Checklist”. Data were analyzed with Pearson’s r.

Planned coping was associated with evaluations of opportunity (r=0.78) and threat to the future (r=0.61). Despite the deteriorating health status of most of the children, women reported a high degree of subjective control. This might be related to outside help. Participants stated that helping by the family, doctors, and psychologists was essential. Unexpectedly, the “need for a quick and active response” score correlates with that for the coping strategy “fantasizing” (r=0.62). This can be explained by the depletion of resources; deprivation of sleep and active rest is often observed. An important feature is that half of the participants report high self-blame.

We suggest that self-blame, an analysis of opportunities, and probable future scenarios are important psychotherapy targets for mothers of terminally ill children. The consequences of threat appraisal are twofold: admitting the threat can be painful, but it also mobilizes one’s energy. Funding: The study was funded by RFBR, project number 20-013-00838.

No significant relationships.

The relationship between behavioral changes and the menstrual cycle in women at a reproductive age has been investigated in several studies; women during every menstrual cycle experience noticeable changes in levels of sex hormones which are consequently reflected on their mood and behavior. The relationship between the menstrual cycle and the emotion recognition processing has been also studied.

The aim of this study was to examine if differences exist between women with Premenstrual Dysphonic Disorder (PMDD) and women without PMDD in Emotion recognition processing across menstrual cycle.

We examined 26 women with a PMDD and 30 women without PMDD, who have both visited the Mental Health Centre (aged 18-35 y.o., right handed, educational level >9 y., regular cycle duration). Women were clinically interviewed (DSM-V); also the Emotion Recognition Task (ERT) was administered in the luteal and the follicular phase.

Women with PMDD showed significant differences in emotion recognition depending on the the luteal and the follicular phase (according to estradiol and progesterone level) whereas women without PMDD did not present significantly different responses to the emotional stimuli.

Our findings suggest that there is an effect of PMDD on emotional facial recognition across the two phases of the menstrual cycle. Thus, the importance of incorporating ERT in the formal clinical examination of PMDD is highlighted.

No significant relationships.

No significant relationships.

There is limited research in adolescent at risk for psychosis. The new criteria of Attenuated Psychosis Syndrome (APS) of Diagnostic and Statistical Manual of Mental Disorders- 5 (DSM-5) have not been validated.

The aims of this study were to: 1) characterize adolescent’s profile with APS (DSM-5 APS) compared to adolescents with early onset psychosis (EOP) and with other psychiatric disorders (non-APS); 2) to estimate their long-term risk of transition to psychosis and prognostic accuracy of DSM-5 APS.

243 adolescents, aged 12-17, were included (October 2012- July 2019) and dived in three sub-groups (110 DSM-5 APS, 31 EOP, 102 non-APS). All underwent a comprehensive assessment evaluating: sociodemographic characteristics, family and personal history of any DSM-5 psychiatric disorders, psychopathological assessment and level of functioning. An annual follow-up evaluation was carried out (up to 7 years) including a clinical interview to investigate DSM-5 criteria for transition to psychosis.

DSM-5 APS adolescents had on average higher comorbid disorders (2.3) and intermediate psychopathological and functioning profile between non-APS/EOP. The cumulative risk of transition at 1,2,3, 4-5 years was 13%, 17%, 24.2%, 26.8% and 26.8% in DSM-5 APS group, 0%, 0%, 3.2%, 3.2% and 3.2% in the non-APS. The 5-year prognostic accuracy of the DSM-5 APS in adolescent was adequate (Area Under the Curve=0.77) with high sensitivity (91.3%) and suboptimal specificity (63.2%).

The DSM-5 APS diagnosis can be used to detect help-seeking adolescents at risk of psychosis and predict their long-term outcomes, leading the way to new preventive approaches.

The authors declare that they do not have a significant financial interest, consultancy or other relationship with products, manufacturer(s) of products or providers of services related to this abstrac.

No significant relationships.

Self-determination is the developmental task (R. Havighurst) in youth leading to personality psychological well-being and health.

The aim was to study the worldview attitudes in Russian youth who are Tolkien fans.

The techniques were completed by 121 students; 17-28 age (M = 21.7; M/F= 35.5 / 64.5 %); 81 (66.9%) subscribers of the Vkontakte communities dedicated to the work of J.R.R. Tolkien. 1. Incomplete Sentences by Sacks-Levy in authors’ version 2. World assumptions scale (R. Janoff-Bulman) (Padun, Kotelnikova, 2007) 3. Purpose-in-Life Test (J. Crumbaugh, L. Maholick) (Leontiev, 2000) 4. The Level of Escapism (Teslavskaya, Savchenko, 2019).

Three groups of respondents differing in their attitude to the literary genre of fantasy («fans», «amateurs», «indifferent») were identified. Respondents consider the world to be moderately benevolent, and fair, and themselves quite good people, able to control most of the events taking place in their lives. They are sure that they are often lucky in life. «Fans» have the highest tendency to escapism, the most pessimistic view of the world, with a more positive image of the person compared to other respondents. «Fans» consider their lives less emotionally rich and productive, compared to the assessment of their lives by peers of other groups.

The level of escapism expression in fantasy literature fans are higher than in respondents who do not distinguish this genre as preferred. A new theoretical and empirical work is that worldviews can be monitored and taken into account in practical psychological working with at-risk young people.

No significant relationships.

The COVID-19 pandemic has dramatically affected ones well-being. ICU healthcare providers are particularly concerned by this impact which includes physical, mental and socioeconomic repercussions. Others health dimensions could be deeply affected but not well explored such as the psycho-sexual status.

The aim of this study was to assess sexual health status among ICU healthcare providers.

This was a cross-sectional study enrolling Tunisian ICU healthcare providers and conducted between July and September 2021. Data collection was based on a self-administrated questionnaire. To assess sexuality, Arabic validated versions of the IIEF-15 and the FSFI was used for male and female respectively. The Fear of COVID-19 Scale and the Rosenberg Self-esteem questionnaire were also used.

Twenty ICU workers (13 physicians and 7 nurses) were enrolled. The mean age was 28.2 years and the sex ratio was 2.3. All participants were involved in COVID-19 crisis management and 80 % reported an increase in their workload. The mean Rosenberg scale was 27 suggesting a low self-esteem. The mean Covid19 Fear Scale was 26 ± 2. For the IIEF-15 the mean score was 17 ± 3 (moderate erectyl dysfunction) and the most damaged dimension was the intercourse satisfaction. For the FSFI scale, the mean was 23 ± 5 witch (a low sexual dysfunction). A high sexual desire with a lack in the satisfaction dimension was reported in 90% of cases. Only 4 participants have consulted a sexologist.

COVID-19 has a serious sexual impact in ICU healthcare providers justifying urgent psychological interventions.

No significant relationships.

Youth integrated care services were developed to overcome common barriers to mental health treatment. Satisfaction is key for services utilization and engagement.

To study users satisfaction with youth integrated care service, “Headspace”, throughout the course of treatment and its correlation with clinical and demographic characteristics and service utilization.

A sample of 112 participants ranging between ages 12-25 who attended the Headspace clinic between March 2016 and June 2018 were assessed in the middle (after 7 sessions) and end of treatment (n=71).

Participants expressed high levels of satisfaction across all service aspects at the middle and end of treatment. The highest rate of satisfaction was with the centre’s staff and the lowest with personal outcomes. A repeated measures ANOVA analysis revealed that only satisfaction with personal outcomes improved significantly over time Length of wait to begin treatment and parental engagement y were negatively correlated with youth satisfaction.

Satisfaction rates of Headspace among youth are high from the start and with their outcomes increase over time. Youth satisfaction with the staff’s attitude and approach and satisfaction with accessibility suggest the service achievement in addressing barriers of help seeking in youth.

No significant relationships.

Cardiovascular disease (CVD) causes staggering losses in quality adjusted life years worldwide.1 Among patients in the Danish psychiatric hospital setting, heart disease is associated with a decrease in life expectancy of 5.1 years.2 The causes underlying this association are likely manifold. For example, severe mental illness is associated with unhealthy lifestyle.3 Furthermore, psychiatrists may focus predominantly on the treatment of mental illness and have less emphasis on detection and prevention of physical illness.4 If patients at elevated risk of CVD are pointed out automatically, this may lead to better preventive medicine.

To predict which patients develop cardiovascular disease using machine learning.

We obtained data on all psychiatric hospital contacts in the Central Denmark Region since the initiation of the current EHR system (MidtEPJ). These span from 2011 to 2021 and cover 120,000 patients, of which 3,000 patients developed severe CVD (stroke or coronary event) follow-up. We will train a variety of models (random forests, SVM, deep neural nets) to predict CVD within one year from a planned contact to hospital.

The modelling is currently underway, intermediary results are expected in January.

We explore whether predicting CVD is feasible using state-of-the-art technologies and a uniquely detailed dataset. This may pave the way for machine learning to act as a clinical support decision system, since we’re only training on data that is available in a live, clinical context.

References

1: Khan 2019

2: Erlangsen 2017

3: Scott 2011

4: Fagiolini 2009

No significant relationships.

Psychiatric conditions can be both a symptom and a consequence of physical disease. Although understanding of this is important for health care delivery, coverage of the relationship between physical and psychiatric illness in undergraduate medical education is sparse. This relationship is particularly pertinent in neurological disorders, where psychiatric symptomatology is commonplace. As part of a student project, the author was tasked with developing accessible teaching materials to increase interest and understanding among medical students, using podcasts.

The aim was to develop podcasts which explored the relationship between psychiatric and neurological illness, for use in undergraduate psychiatric training.

Literature reviews were performed on podcasting in medical education to identify the optimal methods of production to maximise educational value, and on topics covered in podcasts to inform the interview questions. Experts in the relevant areas were contacted for recorded interviews, later used to create podcasts.

Four interviews were conducted between the author and consultant neurologists specialising in the specific neurological condition. A podcast was produced for each of the following topics: depression in multiple sclerosis, frontotemporal dementia in motor neurone disease, Lewy body dementia, and dissociative seizures.

Psychiatric and physical illness are often intertwined. As the prevalence of psychiatric illness rises, it is becoming increasingly important that this connection is recognised, in order to improve patient experiences and outcomes. Novel teaching modalities, such as podcasts, can provide additional ways to support medical education on this important topic.

No significant relationships.

Marfan syndrome is an autosomal dominant systemic disorder with connective tissue defects in multiple organ systems. Cardinal manifestations of this syndrome involve the cardiovascular, the skeletal and the ocular system. Interestingly, many cases of patients with Marfan syndrome and schizophrenia have been reported.

Discuss the etiological link between Marfan syndrome and schizophrenia

Presentation of a clinical case illustrating the comorbidity between schizophrenia and marfan syndrome. A search was conducted in PubMed database using the terms : schizophrenia AND Marfan syndrome.

Ms JW a 36-year- old single women, she had schizophrenia since the age of 20 years, she was hospitalized in our service for psychotic relapse in a context of treatment discontinuation. She had a personal history of persistence of the ductus arteriosus for which she had been operated during her childhood, a scoliosis operated and multiple pathological fractures. On mental status examination, she was distressed and hallucinated, She had disorganized thought processes and a paranoid delirium. On physical examination, she had features suggestive of Marfan syndrome such as crowded teeth, a high arched palate, arachnodactyly , hyperlaxity and a high myopia. We don’t dispose genetic evaluation for marfan syndrom because of the nonavaibility of facilities to perform genetic analysis. Several studies have indicated that psychiatric symptoms might be part of the clinical profiles of marfan syndrom. However, their relationship and underlying pathogenesis are not easily clarified.

Co-occurrence of marfan syndrom and schizophrenia might be explained by some shared etiological pathways between both disorders.

No significant relationships.

Endorsing conspiracy theories seems to constitute a major feature of contemporary collective anti-vaccine movements (Vignaud & Salvadori, 2019). As revealed by the COVID-19 pandemic, this contributes to increased worldwide vaccine hesitancy (de Figueiredo et al., 2020).

The present work aims at providing novel insight into the collective psychological underpinnings of conspiracy-based vaccine discourses.

Our approach is inspired by Jung’s view that human groups produce narratives to project their collective conflicts (e.g., social, religious, political) onto reality. We analyze these projections in relation to the “halo effect” phenomenon, namely taking metaphorical extensions of (scientific) concepts at face value (e.g. Keller, 1995). Accordingly, we discuss one version of “the Great Reset” theory, claiming that COVID-19 vaccines are used by “the elite” to control behavior and abolish fundamental freedoms.

Our analysis suggests that Western societies are manifesting some of their existential concerns through anti-vaccine discourse. In “the Great Reset” narrative, characters (people, vaccines, elites, immune systems, etc.) and plot can be read as symbols of, respectively, structural elements of the collective psyche (socio-cultural values, aggressive drives, death anxiety, psychic defenses, etc.), and dynamic interrelations among these elements.

Conspiracy theories can be understood as shared narratives serving the purpose of giving shape to collective fears. Within such a framework, references to “vaccines” and “immunity” are the manifestations of a state of crisis of collective psychic defenses.

No significant relationships.

Schizophrenia and bipolar disorder are severe mental illnesses that are known to have a considerable overlap in underlying pathophysiological mechanisms. More specifically, disturbances in the kynurenine pathway have been hypothesized as processes bridging altered immune responses and clinical manifestations of these illnesses.

The aim of this study was to investigate the abnormalities in serum kynurenine metabolites in schizophrenic and bipolar patients and the impact of clinical factors.

Four patient groups were included in the current study: 1) Acute bipolar inpatients (n=205); 2) stable bipolar outpatients (n=116); 3) acute schizophrenia inpatients (n=111) and 4) stable schizophrenia outpatients (n=75); and one healthy control group (n=185). Clinical symptoms were established using symptom severity scales. The quantitative determination of serum kynurenine metabolites was performed using LC-MS/MS. General linear model and multivariate linear regression analyses were used to perform the statistical analysis with JMP Pro 15.

In line with previous research, the results indicate that serum kynurenine metabolites are disturbed in schizophrenic and bipolar patients compared to healthy controls. Whereas no differences were observed between schizophrenia and bipolar disorder, illness state and duration of illness clearly impacted kynurenine metabolite levels. Acutely ill patients had significantly lower levels compared to stable patients, which seemed to be driven by psychotic symptoms.

To conclude, the results confirm the involvement of the kynurenine pathway in the pathophysiology of schizophrenia and bipolar disorder by lowered peripheral kynurenine metabolite level. In addition, an important role of acute psychotic symptoms and longer illness duration on these metabolite aberrances is demonstrated.

No significant relationships.

The association between low birth weight and attention problems in childhood has been replicated many times (e.g. Momany, Kamradt, & Nikolas, 2018). However birth weight is unlikely the aetiological start-point of this association, as birth weight is itself the product of many prenatal factors e.g. gestational complications, maternal toxin exposure during pregnancy and basic demographics.

We explore (1) which prenatal factors best predict attention problems in two independant population-based cohorts of children (2) which associations, if any, are moderated by sex and (3) we report accuracy statistics of our prenatal prediction algorithm for attention problems.

Participants were children aged 9 from ABCD study from the United States (N > 9,000) and the Growing Up in Ireland (GUI) study from Ireland (N > 6,000). Selected variables included familial pscyhiatric history, maternal smoking during gestation, prescription and non-prescription drug-use during gestation and a variety of gestational complications. All interactions with sex were also included. We used 5-fold cross-validation and elastic net regression (glmnet) to identify the optimal predictors of attention problems (measured by CBCL and SDQ).

Strongest predictors of attention problems in the U.S. cohort included male sex, number of drugs used during pregnancy, number of family members with a history of mental illness, and number of gestational complications. Sex interacted with several of these risks. Protective factors included being a twin/triplet, being Asian, having higher household income and higher parental education level.

Several risk factors for childhood attention problems were identified across both cohorts, supporting their generalizabilty. Other findings were cohort-specific.

No significant relationships.

Several studies describe that the coexistence of a substance use disorder with another psychiatric condition or “dual disorder” (DD) is associated with a worse evolution at all levels, including a greater burden of medical illnesses and greater mortality.

To describe the presence of DD and related factors in patients admitted to a General Hospital that required assessment by a psychiatry service.

A descriptive study that includes patients admitted to the Hospital del Mar in Barcelona for all medical-surgical reasons and attended by the specific addiction psychiatry consultation service between January 2016 and October 2021. Sociodemographic and clinical data are collected including the history of consumption and the diagnosis of dual disorder. Chi-square test was used for comparison between groups.

The sample was 1796 patients (Women: 345. Mean age: 50.3 years; SD: 12.6). 43.7% of the sample presented DD, with axis 1 disorders being the most frequent. There was an association of DD to factors as: being woman (54 vs 41.2% p <0.001), HIV positive serologies (54 vs 42.7% p <0.001), being homeless (49 vs 31.7% p <0.001) and cocaine consumption compared to other substances (53.4 vs 39.8% p <0.001).

In our sample, almost half of patients had DD. The representation of women was significantly lower, however they presented a higher proportion of DD. In this study we describe an association of DD with other biopsychosocial problems, and further studies are necessary to determine in which sense they are related and optimize patient care.

No significant relationships.

Globalization and increased competition in the engineering profession induce to work longer and harder, which predisposes to workaholism or work addiction. Identifying individual factors associated with workaholism could help to maintain the mental health at work.

The aim of this study was to assess the prevalence of workaholism and its associated socio-demographic and historic factors among Tunisian engineers.

A cross-sectional descriptive and analytical study conducted among Tunisian engineers during July 2021. The data were collected by an online questionnaire including the socio-demographic and historic information and the “the Work Addiction Risk Test” (WART) which was used to assess the workaholism.

A total of 52 engineers participated in this study (40.4% female and 59.6% male). The average age was 30.75 years (SD=6.25 years). Concerning marital status, thirty-five engineers (67.3%) were single. Of the participants, 17.3% had a history of chronic somatic-disorders and 25 % of them had a history of a psychiatric disorder, such as depressive disorder in 11.5% of cases. The prevalence of workaholism in Tunisian engineers was 23.1%. Workaholism was associated to older age with no significant difference (p = 0.11). The analysis showed that workaholics had more history of depressive disorder (p = 0.02) compared to non-workaholics. However, no significant difference was found by the other socio-demographic factors according to workaholism.

Workaholism is a significant phenomenon among Tunisian engineers. It may depend of personal characteristics and induce negative consequences on mental health and lead to depression.

No significant relationships.

Depression and suicidal behaviour are major public health problems everywhere but particularly in Hungary where until 2000 the suicide rate was among the highest in the world.

To analyse the possible causes of declining national suicide rate of Hungary.

Review of the scientific literature on Hungarian suicide scene published in the last 40 years.

The peak of Hungarian national suicide rate was in 1985 (46/100.000) but due to a steady and continuous, year by year decline, in 2019 it was only 16/100.000, which represents a more than 65% decrease. Rate of unrecognised/untreated mood disorders, availability of health/psychiatric care, antidepressant and lithium prescription, unemployment, smoking and alcohol consumption as well as lithium and arsenic contents of drinking water were the most investigated possible determinants of suicide mortality of the country. More widespread and effective treatment of psychiatric/mood disorder patients, decreased rate of unemployment and smoking as well as the continuously improving living standards were the most important contributors to the great decline of the national suicide rate. However, in 2020 – the first year of the COVID-19 pandemic – the national suicide rate rose by 16%, which was almost totally accounted for by the increase of suicides among males.

Suicidal behaviour is preventable in many cases, but as it is a complex, multicausal phenomenon, its prevention should involve several medical/psychiatric, psychosocial and community interventions.

No significant relationships.

Parental reflective function is the ability of a parent to attribute mental states to their child and to themselves. The Parental Reflective Functioning Questionnaire is widely used for the measurement of this construct, the adolescent version of which can be used by parents of children aged 12-18.

The aim of our research was to adapt the adolescent version of The Parental Reflective Functioning Questionnaire to the Hungarian language.

In our study 240 mothers completed the adolescent version of The Parental Reflective Functioning Questionnaire (PRFQ-A), and the Reflective Function Questionnaire (RFQ).

Confirmatory factor analysis did not confirm the original three-factor structure. The principal component analysis resulted in a two-factor structure. Factors corresponded to the original questionnaire’s certainty in mental states (Alpha = .81) and interest and curiosity subscales (Alpha = .70). When analyzing the relationship between parental reflective function and reflective function, the subscales of the parental reflective function questionnaire were examined with two types of median coding in addition to polar coding. During the first median coding, the frequency of scores in the middle of the scales reflected optimal mentalization, while the frequency of extreme values on the scales corresponded to less favorable reflective functioning. With the second median coding, hypermentalization and hypomentalization subscales were also created. The second median transcoding proved to be the most suitable for capturing the relationship between RFQ and PRFQ-A.

The questionnaire proved to be a reliable measure on the Hungarian sample and we recommend using the additional subscales.

No significant relationships.

Increase in affective and somatic complaints during pandemic is considered as related to experienced stress (Wang et al., 2020, Roy et al., 2020, Robillard et al., 2020). Expression or suppression of emotions related to pandemic could affect the vulnerability of people to stressful situations (Gross, Thompson, 2007, Roberts et al., 2008).

The aim was to reveal a role of suppression / expression emotions regarding pandemic in the changes in somatic and affective complaints in people without coronavirus during lockdown.

In May 2020 110 people 18-65 years old (61.2% females) without coronavirus appraised their strategy of dealing with different emotions regarding pandemic on the 1-5 scale from emotional expression to hiding and suppression (Cronbach’s alphas) and 26 somatic and emotional symptoms including sleep-related symptoms, daytime functioning, affective symptoms, general physical condition (Cronbach’s alphas .81-.90). In December 2020 they reappraised 26 complaints.

There were no statistically significant changes in somatic and affective complaints during May-December 2020 (p>.20). Increase in sleep-related complaints (β=.23, p<.05, ΔR2=5.0%) and complaints regarding general physical condition (β=.32, p<.05, ΔR2=10.0%) were more pronounced in those reporting higher expression of emotions related to COVID.

People with higher emotional reactivity to pandemic situation tend to report increase in sleep-related problems and general worsening of their physical condition during lockdown. Research is supported by the Russian Foundation for Basic Research, project No. 20-013-00799.

Research is supported by the Russian Foundation for Basic Research, project No. 20-013-00799