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The enduring impact of the COVID-19 pandemic on mental health and its implications for COVID-19 vaccine uptake necessitate comprehensive investigation. We aimed to characterize the persistence of moderate to severe anxiety and depression symptoms from July 2020 to July 2023, explore demographic associations with symptom persistence, and assess how these symptoms affected COVID-19 vaccination uptake between May 2021 and July 2023.
Methods
Participants from the national community-based CHASING COVID Cohort were enrolled between March and June 2020 and completed quarterly follow-ups until December 2023. Scores ≥10 on the Generalized Anxiety Disorder 7-item and the Patient Health Questionnaire 8-item at 14 follow-up assessments indicated moderate to severe anxiety and depression symptoms, respectively. Missing scores were imputed. Persistent anxiety and depression were defined as experiencing moderate to severe anxiety and depression symptoms ≥7 out of 14 follow-up assessments, respectively.
Results
Among 4,851 participants, 15.9% experienced persistent anxiety symptoms and 19.3% persistent depression symptoms from July 2020 to July 2023. Demographic factors associated with symptom persistence included younger age, female or non-binary gender, Hispanic ethnicity, lower education level, household income <$100k, presence of children <18 in the household, greater healthcare barriers and comorbidities. Participants with ongoing moderate to severe anxiety and depression symptoms had 0.95 (95% CI: 0.94, 0.97) and 0.95 (95% CI: 0.93, 0.96) times rates of receiving additional COVID-19 vaccine doses between May 2021 and July 2023, respectively.
Conclusions
Customized support for individuals with mental disorders may mitigate barriers to vaccine uptake. Further investigation is warranted to validate these findings and inform targeted interventions.
What are we? What owns our thoughts and experiences? Are we anything at all? After an introduction, Section 2 assesses a 'no-bearer' theory of experience, and the 'no-self' contention that self-representations are about no real entity, before introducing a positive hypothesis about the objects of our self-representations: the 'animalist' claim that we are biological organisms. Section 3 discusses the classic challenge to animalism that brain transplantation is something we could survive but no animal could survive. This challenge introduces positive alternatives to animalism, as well as animalist responses, including one which questions the assumption that psychology is irrelevant to organism persistence. Section 4 surveys a 'thinking parts' problem and conjoined twinning and commisurotomy, also considered problematic for animalism. The interpretation of these cases revisits questions about bearers of experience, objects of self-representation, and the relation of biology and psychology. This title is also available as Open Access on Cambridge Core.
This paper distinguishes news about short-lived events from news about changes in longer term prospects using surveys of expectations. Employing a multivariate GARCH-in-Mean model for the US, the paper illustrates how the different types of news influence business cycle dynamics. The influence of transitory output shocks can be relatively large on impact but gradually diminishes over two to three years. Permanent shocks drive the business cycle, generating immediate stock price reactions and gradually building output effects, although they have more immediate output effects during recessions through the uncertainties they create. Markedly different macroeconomic dynamics are found if these explicitly identified types of news or uncertainty feedbacks are omitted from the analysis.
This article introduces a model that harnesses praxis as a powerful tool for critique, knowledge, and action within the realm of public archaeology. The adopted framework focuses on persistence as a middle-range methodology that bridges the material past to activist and collaborative-based projects. Recent research at Mission La Purísima Concepción in Lompoc, California, shows the effectiveness of this model and its real-world application. Visitors to California missions encounter the pervasive “Mission Myth”—a narrative that systematically overlooks and marginalizes Indigenous presence while perpetuating ideas of White hegemony and Eurocentrism. Archaeological excavations in the Native rancheria and collaboration with members of the Chumash community help resist notions of Indigenous erasure. By activating notions of persistence through public archaeology, this study contributes to dismantling entrenched terminal narratives, paving the way for a more accurate representation of the past and fostering a more inclusive archaeological practice.
Research on mobile-assisted language learning (MALL) has revealed that high rates of attrition among users can undermine the potential benefits of this learning method. To explore this issue, we surveyed 3,670 adult MALL users based on the Unified Theory of Acceptance and Use of Technology (UTAUT) and also conducted an in-depth analysis of their historical app usage data. The results of hierarchical k-means cluster analysis and recurrent event survival analysis revealed three major findings. First, three distinct profiles of learners were characterized by different MALL acceptance and engagement experiences. Second, those with greater MALL acceptance displayed more intense, frequent, and durable app usage (behavioral engagement). Lastly, high levels of MALL acceptance were associated with more frequent pauses in app usage but also (a) longer active usage, (b) shorter breaks before returning to the app, and, ultimately, (c) fewer dropouts. We argue that persistence is a multidimensional process involving cyclical phases of engagement, disengagement, dormancy, and reengagement, with each aspect, like intensity, frequency, and duration, building up cumulatively over time. Implications for promoting persistent MALL engagement are discussed.
Debate regarding the continuity of Cypriot political forms from the Late Bronze Age to the Cypro-Archaic is persistent, resulting in a scholarly divide with few signs of resolution. This article reviews the historiography of political forms proposed for Cyprus as the essential context for this debate. It considers several major themes that emerge from the debate: the use of anthropological models for state formation, regionalism, social networks, and the nature of spatial power. The author views the debate as centred on two equally valid motivations: using related social science theory to enhance archaeological explanation and emphasizing Cypriot autonomy. These motivations need not be set in opposition but, together, illustrate the island's unique history and provide the basis for vibrant scholarship.
This article explores the notion of immortality in Jaina philosophy by focusing on the problem of the persistence of the self. It considers the concept of persistence within the broader context of Jaina metaphysics and its specific application to living beings. The article analyses the relationship between the immaterial self and its material body to determine which aspects of living beings can be deemed immortal or persisting beyond death. It also investigates the state of liberation as an immortal condition. Drawing from the Tattvârtha-sūtra and four of its commentaries, the article demonstrates the complexity of the Jaina treatment of the issue of the self's persistence over time and its commitment to the doctrine of non-one-sidedness. It also shows that Jaina philosophers deal with this critical philosophical problem in a way that reflects their engagement with the intellectual debates of their time.
A history of local inclusive institutions is correlated with higher levels of democracy today. However, it is unclear whether this reflects the effect of historical institutions on democracy or a prior common cause. Using a geographic natural experiment, this letter demonstrates that historical experience with inclusive institutions is related to less support for autocratic parties in nineteenth- and twentieth-century Germany. This suggests that electoral support for political parties that seek to subvert democracy can be influenced by pre-modern institutions even when they were destroyed prior to the introduction of democracy.
We study the asymptotic growth rate of the labels of high-degree vertices in weighted recursive graphs (WRGs) when the weights are independent, identically distributed, almost surely bounded random variables, and as a result confirm a conjecture by Lodewijks and Ortgiese (‘The maximal degree in random recursive graphs with random weights’, preprint, 2020). WRGs are a generalisation of the random recursive tree and directed acyclic graph models, in which vertices are assigned vertex-weights and where new vertices attach to $m\in\mathbb{N}$ predecessors, each selected independently with a probability proportional to the vertex-weight of the predecessor. Prior work established the asymptotic growth rate of the maximum degree of the WRG model, and here we show that there exists a critical exponent $\mu_m$ such that the typical label size of the maximum-degree vertex equals $n^{\mu_m(1+o(1))}$ almost surely as n, the size of the graph, tends to infinity. These results extend results on the asymptotic behaviour of the location of the maximum degree, formerly only known for the random recursive tree model, to the more general weighted multigraph case of the WRG model. Moreover, for the weighted recursive tree model, that is, the WRG model with $m=1$, we prove the joint convergence of the rescaled degree and label of high-degree vertices under additional assumptions on the vertex-weight distribution, and also extend results on the growth rate of the maximum degree obtained by Eslava, Lodewijks, and Ortgiese (Stoch. Process. Appl.158, 2023).
Based on biochemical kinetics, a stochastic model to characterize wastewater treatment plants and dynamics of river water quality under the influence of random fluctuations is proposed in this paper. This model describes the interaction between dissolved oxygen (DO) and biochemical oxygen demand (BOD), and is in the form of stochastic differential equations driven by multiplicative Gaussian noises. The stochastic persistence problem for the model of the system is analysed. Further, a numerical simulation of the stationary probability distributions of BOD and OD by approximations of the stochastic process solution is presented. These results have implications for the prediction and control of pollutants.
We use an online experiment to study the relative effect on voter behavior of a candidate’s voice pitch and policy stance. We demonstrate a strong voice-pitch bias: between candidates who are identical in every other aspect, voters are more likely to choose the one with the lower voice-pitch, and more so in elections between men than women candidates. We then introduce a novel phenomenon: persistence of voice-pitch bias is the amount of policy difference needed to compensate for voice-pitch bias. While persistence is also gender-dependent, the effect is now reversed: voice-pitch bias is more persistent in elections between women than men candidates. As a possible mechanism, we show that voters perceive candidates with lower voice-pitch as more competent and trustworthy.
The canonical income process, including autoregressive, transitory, and fixed effect components, is routinely used in macro and labor economics. We provide a guide for its estimation using quasidifferences, cataloging biases in the estimated parameters for various $N$, $T$, initial conditions, and weighting schemes. Using Danish administrative data on male earnings, estimation in quasidifferences yields divergent estimates of the autoregressive parameter for different weighting schemes, which conforms to our simulation results when the variance of transitory shocks is higher than that of persistent shocks, true persistence is high, and the persistent component’s variance in the first sample year is nonzero. We further apply quasidifferences to the data from a calibrated lifecycle model and find significant biases in the persistence of shocks and their insurance. Estimation of the income process using quasidifferences is reliable only when the variance of persistent shocks is higher than that of transitory shocks and the moments are equally weighted.
The constitution of a political economy is not a fixed constellation of relationships but a set of principles governing which relative positions and transformations are feasible under the existing constitutional arrangements. Constitutional principles imply that persistence and change are closely intertwined: a degree of persistence ensures the identity and stability of a political economy, while openness to transformation is necessary to allow resilience vis-à-vis shocks and adjustment to societal change. Each economic body is identified by a particular division of labour, representation of interdependencies, and dispositions of individuals and groups in the economy. Dispositions and interests are also central in the constitution of the political body, which leads to a definition of systemic interest and of the range of variation within which a given systemic interest can accommodate different constellations of partial interests. This conception of political economy makes principles of economic ordering essential to the life of the polity, and acknowledges the existence of political alliances or conflicts arising from division of labour between centres of agency in the economic sphere. The consideration of matches and mismatches between the two spheres opens a line of investigation that is central to understanding the history and prospects of political economies.
This chapter problematises the notion of resilience as continuation with adaptability, suggesting that it requires specifying in advance the essential attributes of a global governance body, which would have to remain largely intact for adaptation to changing circumstance to count as resilience. The chapter therefore identifies those essential attributes for the International Electro-technical Commission (IEC). The chapter then theorises resilience of a private rule-making body as a function of its capacity and capability for autonomous agency in pursuit of its organizational self-interest, the embeddedness of the rule-making body among its stakeholders, and its leadership’s ambition to ensure the organisation’s survival. It shows that these characteristics helped the IEC to achieve resilience in the face of numerous and diverse challenges from technological changes, the emergence of competing SDOs and geopolitical changes accompanied by power transitions in the world economy, including the rise of China. The unresolved challenges of meaningful consumer participation and better gender balance in international standardization suggests, however, that past resilience is only partially predictive of future resilience.
In producing linguistic variation, language users display a tendency to reuse the same variant. This paper compares the empirical properties of different types of repetitiveness in a single case study: locative variation in Chengdu Mandarin. Using conversational data from sociolinguistic interviews, we ask whether within-speaker repetitiveness (persistence) and cross-speaker repetitiveness (convergence) behave similarly with respect to (1) their sensitivity to the linguistic similarity of the prime and target, and (2) their tendency to decline with greater temporal distance between the prime and target. Our results suggest that intraspeaker persistence and interspeaker convergence behave similarly in both respects. We therefore propose that repetitiveness has a common underlying mechanism within and across speakers and encourage future work aimed at testing this hypothesis across other variables and varieties.
Although non-suicidal self-injury (NSSI) is known typically to begin in adolescence, longitudinal information is lacking about patterns, predictors, and clinical outcomes of NSSI persistence among emerging adults. The present study was designed to (1) estimate NSSI persistence during the college period, (2) identify risk factors and high-risk students for NSSI persistence patterns, and (3) evaluate the association with future mental disorders and suicidal thoughts and behaviors (STB).
Methods
Using prospective cohorts from the Leuven College Surveys (n = 5915), part of the World Mental Health International College Student Initiative, web-based surveys assessed mental health and psychosocial problems at college entrance and three annual follow-up assessments.
Results
Approximately one in five (20.4%) students reported lifetime NSSI at college entrance. NSSI persistence was estimated at 56.4%, with 15.6% reporting a high-frequency repetitive pattern (≥five times yearly). Many hypothesized risk factors were associated with repetitive NSSI persistence, with the most potent effects observed for pre-college NSSI characteristics. Multivariate models suggest that an intervention focusing on the 10–20% at the highest predicted risk could effectively reach 34.9–56.7% of students with high-frequency repetitive NSSI persistence (PPV = 81.8–93.4, AUC = 0.88–0.91). Repetitive NSSI persistence during the first two college years predicted 12-month mental disorders, role impairment, and STB during the third college year, including suicide attempts.
Conclusions
Most emerging adults with a history of NSSI report persistent self-injury during their college years. Web-based screening may be a promising approach for detecting students at risk for a highly persistent NSSI pattern characterized by subsequent adverse outcomes.
Psychotic experiences (PEs) frequently occur and are associated with a range of negative health outcomes. Prospective studies on PEs are scarce, and to date no study investigated PE prevalence, incidence, persistence, their risk indicators, and psychiatric comorbidity, in one dataset. Furthermore, most studies are based on self-report, and it is unclear how this compares to clinical interviews.
Methods
Data are used from the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2), a psychiatric cohort study among a representative sample of adults (baseline characteristics: N = 6646; 49.6% female; 18–64 years). Results are presented for self-reported and clinically validated PEs. Associations are assessed for mental disorders, socio-demographic, vulnerability, physical health, and substance use factors.
Results
Based on self-report, at baseline 16.5% of respondents had at least one PE in their lifetime, of those, 30.1% also reported a PE at 3-year follow-up. 4.8% had a first PE at 3-year follow up. The 3-year prevalence of PE was associated with almost all studied risk indicators. Generally, the strongest associations were found for mental health disorders. Prevalence and incidence rates were two to three times higher in self-report than in clinical interview but results on associated factors were similar.
Conclusions
Validated prevalence and incidence estimates of PE are substantially lower than self-reported figures but results on associated factors were similar. Therefore, future studies on associations of PEs can rely on relatively inexpensive self-reports of PEs. The associations between PE and mental disorders underline the importance of assessment of PE in general practice.
Modelling loss reserve data in run-off triangles is challenging due to the complex but unknown dynamics in the claim/loss process. Popular loss reserve models describe the mean process through development year, accident year, and calendar year effects using the analysis of variance and covariance (ANCOVA) models. We propose to include in the mean function the persistence terms in the conditional autoregressive range model for modelling the persistence of claim across development years. In the ANCOVA model, we adopt linear trends for the accident and calendar year effects and a quadratic trend for the development year effect. We investigate linear or log-transformed mean functions and four distributions, namely generalised beta type 2, generalised gamma, Weibull, and exponential extension, with positive support to enhance the model flexibility. The proposed models are implemented using the Bayesian user-friendly package Stan running in the R environment. Results show that the models with log-transformed mean function and persistence terms provide better model fits. Lastly, the best model is applied to forecast partial loss reserve and calendar year reserve for three years.
One of the most important and daunting roles of the early academic is the pursuit of NIH grant funding. Although NIH funding allows for great autonomy and comes with validation and prestige, the process can feel overwhelming even for the most seasoned investigators. Therefore, being armed with information is crucial. Aiming to provide a guide to NIH grants with the early stage investigator in mind, this chapter outlines many of the key issues you will tackle throughout the process. These include: a) Developing Your Idea; b) Finding the Right Mechanism for You and Your Idea; c) Preparing Your Application; d) Submission and Receipt of Your Application; e) The Review Process; and f) Post-Review Strategies. These issues are addressed in light of the recent changes in the NIH grant submission and review process to provide an objective source, complimented by our favorite tips for your consideration.
Persistence realism is the view that ordinary sentences that we think and utter about persisting objects are often true. Persistence realism involves both a semantic claim, about what it would take for those sentences to be true, and an ontological claim about the way things are. According to persistence realism, given what it would take for persistence sentences to be true, and given the ontology of our world, often such sentences are true. According to persistence error-theory, they are not. This Element considers several different views about the conditions under which those sentences are true. It argues for a view on which it is relatively easy to vindicate persistence realism, because all it takes is for the world to be the way it seems to us. Thereby it argues for the view that relations of numerical identity, or of being-part-of-the-same-object, are neither necessary nor sufficient for persistence realism.