Like Peirce, recognized as the “father-founder” of modern semiotics, Welby too, although just recently (despite her influence on important contemporary scholars), is acclaimed as the “mother-founder,” thus entering the pantheon of the “fathers” of language and sign sciences. These great figures share a common approach to sign and language as exponents of what today is recognized as the major tradition in semiotic studies, “interpretation semiotics.” Meaning, understanding, signs, signifiers, utterers, and listeners are described as evolving in live communication, as part of signifying processes in becoming. Signs develop in ongoing interpretive/ translative processes with other signs, signifiers, and signifying processes. Signs are interrelated with values, consequently sense and significance emerge as major investigation areas for studies on meaning. Moreover, both Welby and Peirce evidence the public, social, and intersubjective dimensions of signifying and understanding, and hence also the importance of intercorporeality, dialogism, otherness, ambiguity for healthy communication, and interpersonal relations.